General Study Notes Quiz
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Questions and Answers

What condition is indicated by the ECG pattern in the 4-year-old girl?

  • Paroxysmal supraventricular tachycardia
  • Paroxysmal ventricular tachycardia
  • Stokes-Adams pattern
  • Wolff-Parkinson-White syndrome (correct)

What may occur as a consequence of ventricular tachycardia?

  • May induce ventricular fibrillation (correct)
  • Cured by increased fluid intake
  • Usually begins spontaneously
  • May develop gradually

What is the earliest time meconium should be secreted by a newborn?

  • Within the first 24 hours after birth (correct)
  • Within the first 48 hours after birth
  • Within the first 12 hours after birth
  • Anytime after one week of birth

What does the term 'hematemesis' refer to?

<p>Bloody vomit (A)</p> Signup and view all the answers

Which imaging technique is considered the best for detecting bronchiectasis?

<p>Computed tomography (A)</p> Signup and view all the answers

What is a requirement for proper breastfeeding according to recommended guidelines?

<p>Exclusive breastfeeding for up to 6 months (D)</p> Signup and view all the answers

Which of the following is true about newborn gestation?

<p>Considered timely from 37 to 42 weeks (A)</p> Signup and view all the answers

Which organ is associated with the Gleason capsule?

<p>Spleen (B)</p> Signup and view all the answers

What is the most likely cause of the symptoms presented by the 4-year-old child who ingested a home product?

<p>Ingestion of a medication containing atropine (C)</p> Signup and view all the answers

Which of the following substances is most likely to cause methemoglobinemia in a patient?

<p>Amyl nitrite (D)</p> Signup and view all the answers

What is a useful drug for the prophylaxis of angina of effort in a patient who has increased frequency of angina attacks?

<p>Diltiazem (C)</p> Signup and view all the answers

Which drug is reliably effective against both gonococci and C. trachomatis and safe for the patient?

<p>Cefixime (D)</p> Signup and view all the answers

In a patient presenting with chest pain that occurs during exercise and resolves with rest, what could be a likely underlying condition?

<p>Angina of effort (C)</p> Signup and view all the answers

What is an acceptable treatment for a patient with community-acquired pneumonia and a severe ampicillin allergy?

<p>Levofloxacin (D)</p> Signup and view all the answers

After using nitroglycerin, a patient notes the drug is less effective for treatment of acute attacks over time. What is a potential reason for this?

<p>Increased tolerance to the drug (D)</p> Signup and view all the answers

Which medication among the following is typically used for immediate relief during acute angina attacks?

<p>Sublingual nitroglycerin (A)</p> Signup and view all the answers

Which of the following drugs is NOT considered appropriate therapy for a urinary tract infection caused by E. coli?

<p>Moxifloxacin (C)</p> Signup and view all the answers

Which drug is correctly matched with its adverse effect?

<p>Nitrofurantoin—pulmonary fibrosis (D)</p> Signup and view all the answers

A patient diagnosed with angina pectoris is seeking an agent for long-term management. Which of the following options would be most appropriate?

<p>Long-acting nitrates (C)</p> Signup and view all the answers

What does the presence of brownish cyanosis, marked shortness of breath, and hypotension in a patient suggest?

<p>Methemoglobinemia (B)</p> Signup and view all the answers

What side effect contraindicates the use of trimethoprim–sulfamethoxazole in a pregnant woman?

<p>Kernicterus (D)</p> Signup and view all the answers

Which mechanism is involved in metronidazole's action against Trichomonas infection?

<p>Disruption of DNA (A)</p> Signup and view all the answers

Which drug is most suitable for treating a 67-year-old diabetic man diagnosed with external otitis characterized by purulent exudate and gram-negative rods?

<p>Clindamycin (C)</p> Signup and view all the answers

What syndrome is most likely to occur in a patient suffering from aspirin overdose?

<p>Reye's syndrome (D)</p> Signup and view all the answers

What is a common symptom of a urinary tract infection (UTI) caused by E. coli?

<p>Dysuria (C)</p> Signup and view all the answers

What is the most appropriate initial treatment for a patient with external otitis and a primary diagnosis of gram-negative infection?

<p>Gentamicin plus ticarcillin in the hospital (C)</p> Signup and view all the answers

If a patient receiving amikacin at 5 mg/kg every 8 hours experiences a decline in creatinine clearance to 40 mL/min, what should be the most reasonable adjustment in the treatment plan?

<p>Administer 5 mg/kg every 12 hours (A)</p> Signup and view all the answers

A 24-year-old woman with traveler's diarrhea due to a gram-negative bacillus would likely respond best to which antibiotic?

<p>Ciprofloxacin (A)</p> Signup and view all the answers

What is the most critical factor to consider in the treatment of a patient with gonorrhea who has a history of acute hemolysis due to an antimalarial drug?

<p>Use of alternative antibiotics (D)</p> Signup and view all the answers

For a patient experiencing symptoms of external otitis including edema and purulent exudate, which drug should NOT be prioritized for immediate treatment?

<p>Doxycycline (D)</p> Signup and view all the answers

Which of the following is NOT recommended as a first-line treatment for traveler’s diarrhea caused by gram-negative bacilli?

<p>Vancomycin (C)</p> Signup and view all the answers

How should the management of a gram-negative infection be adjusted if the patient experiences impaired kidney function after starting treatment?

<p>Reduce the dosage or extend the interval between doses (B)</p> Signup and view all the answers

Which process does not occur in hepatocytes?

<p>Production of digestive enzymes (B)</p> Signup and view all the answers

In which situation would you suspect meconium ileus?

<p>Meconium is not excreted in the first 24 hours after birth (A)</p> Signup and view all the answers

What is the diagnostic criterion for pneumonia in children under 2 months with an acute respiratory infection?

<p>Respiratory rate of 60 and more per minute (C)</p> Signup and view all the answers

Which statement about diphenhydramine overdose is most accurate?

<p>More of the drug would be ionized at blood pH than at stomach pH. (B)</p> Signup and view all the answers

What term describes the reduction of active drug amount in the body after administration but before systemic circulation?

<p>First-pass effect (D)</p> Signup and view all the answers

What is the most plausible reason for the lower plasma concentration of morphine when taken orally?

<p>First-pass metabolism reducing active drug (D)</p> Signup and view all the answers

What is a likely side effect for a child with bacterial pharyngitis starting oral antibiotics?

<p>Skin rash or itching (B)</p> Signup and view all the answers

What complication may arise from an overdose of an antihistaminic drug like diphenhydramine?

<p>Altered heart rate inducing tachycardia (B)</p> Signup and view all the answers

What is the primary mechanism through which the drug lowers serum cholesterol?

<p>Increasing the shunting of hepatic cholesterol into bile acid synthesis (C)</p> Signup and view all the answers

Which effect of nitroglycerin best helps alleviate angina in effort-induced cases?

<p>Dilation of coronary arterioles to increase coronary flow (C)</p> Signup and view all the answers

How does a β-adrenergic blocker reduce the severity of angina attacks?

<p>Decreases myocardial oxygen demand (C)</p> Signup and view all the answers

What is the main concern when using a nitroglycerin transdermal delivery system continuously?

<p>Development of tolerance to the vasodilatory effects (A)</p> Signup and view all the answers

For a patient with moderate hypertension and a family history of cardiovascular disease, which drug is likely prescribed?

<p>ACE inhibitor to reduce blood pressure (D)</p> Signup and view all the answers

What is the expected cardiovascular benefit of using nitroglycerin during an angina episode?

<p>Decreased preload through venous dilation (D)</p> Signup and view all the answers

What primary pharmacological action is expected from a β-blocker for angina treatment?

<p>Reduction in heart rate and myocardial oxygen use (B)</p> Signup and view all the answers

What is the primary role of endothelial cell-associated lipoprotein lipase in cholesterol metabolism?

<p>Hydrolyzing triglycerides in lipoproteins (C)</p> Signup and view all the answers

Flashcards

Glucogenesis

The process of converting glucose into glycogen, which is stored in the liver and muscles.

Creating a glycogen supply

The creation and storage of glycogen in the liver and muscles.

Products of blood clotting proteins

The process by which certain proteins in the liver are produced, which are essential for blood clotting.

Absorption

The absorption of a drug from its site of administration into the bloodstream.

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Metabolism

The process by which a drug is broken down in the body, often by the liver.

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Bioavailability

The amount of drug that reaches the systemic circulation after oral administration.

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Excretion

The elimination of a drug from the body, usually through the kidneys.

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Pharmacokinetics

The study of how drugs move through the body, including absorption, distribution, metabolism, and excretion.

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Ventricular tachycardia

A type of tachycardia that originates in the ventricles of the heart. It is characterized by a rapid heart rate and irregular rhythm. It can be caused by various factors, including heart disease, drug abuse, and electrolyte imbalances.

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Wolff-Parkinson-White Syndrome

A condition in which the heart's electrical system sends signals through an abnormal pathway, causing a rapid heart rate. Symptoms can include palpitations, dizziness, and shortness of breath.

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Stokes-Adams Pattern

A sudden loss of consciousness caused by a temporary interruption of blood flow to the brain, usually due to a problem with the heart's electrical system.

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Melena

Dark, sticky, tarry stools, often indicative of upper gastrointestinal bleeding.

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Meconium passage

The expulsion of meconium, the first stool of a newborn, which typically occurs within the first 48 hours after birth.

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Computed Tomography (CT) scan

A method for detecting bronchiectasis, a condition characterized by irreversible dilation of the bronchi, using a high-resolution CT scan.

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Timely Gestation

A term referring to the period of a baby's development in the womb, lasting approximately 38 weeks from conception. A timely gestation falls within the normal range.

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Phenylketonuria (PKU)

A genetic metabolic disorder that prevents the body from breaking down phenylalanine, an amino acid found in protein. Early symptoms include delayed development, seizures, and a musty odor.

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Which drug is effective against both gonorrhea and chlamydia?

This medication is effective against gonorrhea and chlamydia, making it suitable for patients with a suspected dual infection.

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What is a safe treatment for CAP in a patient with a severe ampicillin allergy?

Levofloxacin is a suitable treatment option for community-acquired pneumonia in patients with a severe ampicillin allergy.

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Which antibiotic is NOT recommended for a UTI caused by E. coli?

Levofloxacin is a fluoroquinolone and is not typically used for UTIs.

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Which antibiotic is linked to pulmonary fibrosis?

Nitrofurantoin is associated with pulmonary fibrosis as a potential side effect.

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What side effect of trimethoprim-sulfamethoxazole makes it unsuitable for pregnant women?

Trimethoprim-sulfamethoxazole is contraindicated in pregnancy due to the risk of kernicterus, a condition that can cause brain damage in newborns.

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How does metronidazole act against pathogens?

Metronidazole disrupts DNA, interfering with the replication process of certain pathogens.

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What syndrome is associated with an aspirin overdose?

Aspirin overdose can lead to Reye's syndrome, a serious condition characterized by liver and brain damage.

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What adverse effect can levofloxacin cause?

Levofloxacin can cause an adverse effect called tendinitis, which can lead to tendon rupture.

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What is the best antibiotic for external otitis caused by gram-negative bacteria?

Amoxicillin is a penicillin derivative primarily effective against gram-positive bacteria and some gram-negative organisms. It is not the ideal choice for external otitis, which usually involves gram-negative bacteria.

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Is Clindamycin a suitable treatment for external otitis caused by gram-negative bacteria?

Clindamycin is a lincosamide antibiotic with activity against gram-positive bacteria and some anaerobic bacteria. It is not the first-line treatment for external otitis.

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Is Doxycycline a possible treatment for external otitis?

Doxycycline is a tetracycline antibiotic with broad-spectrum activity against both gram-positive and gram-negative bacteria, including those commonly causing external otitis. It is a possible choice for the treatment of external otitis.

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Is Linezolid a suitable treatment for external otitis caused by gram-negative bacteria?

Linezolid is an oxazolidinone antibiotic mainly effective against gram-positive bacteria, especially MRSA. It's not the best choice for external otitis, which is typically caused by gram-negative bacteria.

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When is Vancomycin used to treat external otitis?

Vancomycin is a glycopeptide antibiotic primarily effective against gram-positive bacteria, especially resistant strains like MRSA. It is not the first-line option for external otitis, which is often caused by gram-negative bacteria.

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How should you adjust amikacin dosage when creatinine clearance declines?

When creatinine clearance declines, amikacin's elimination is impaired, requiring a dosage adjustment to prevent accumulation and potential toxicity.

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What antibiotic is effective for traveler's diarrhea caused by gram-negative bacteria?

Ciprofloxacin is a fluoroquinolone antibiotic displaying excellent activity against many gram-negative bacteria, including those commonly causing traveler's diarrhea. It is a strong candidate for treatment in this situation.

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Is Amoxicillin effective against gonorrhea?

Amoxicillin is a penicillin derivative mainly effective against gram-positive bacteria and some gram-negative organisms. It is not the preferred antibiotic for gonorrhea, usually caused by Neisseria gonorrhoeae.

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Phentolamine

A drug that blocks the effects of alpha-adrenergic agonists, primarily used to treat hypertension and other conditions where vasoconstriction is a problem.

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Angina Pectoris (IHD)

A condition characterized by chest pain caused by inadequate blood flow to the heart muscle, usually during physical exertion.

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Methemoglobinemia

A condition where the blood's ability to carry oxygen is reduced due to the presence of methemoglobin, a form of hemoglobin that doesn't bind oxygen effectively.

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Nitrates (e.g., Nitroglycerin)

A class of drugs that dilate blood vessels and reduce blood pressure, often used to treat angina and hypertension.

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Angina of Effort

A type of angina that occurs during physical exertion and is relieved by rest.

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Prophylactic Drugs for Angina

Drugs that are used specifically to prevent angina attacks, rather than treating them once they have occurred.

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Calcium Channel Blockers (e.g., Verapamil, Diltiazem)

A type of drug that blocks calcium channels in cells, reducing the heart's workload and blood pressure, used in treating angina and hypertension.

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Beta Blockers (e.g., Esmolol)

A type of drug that blocks beta-adrenergic receptors, reducing the heart's workload and blood pressure, used in treating angina and hypertension.

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How does this drug lower cholesterol?

This drug works by reducing the levels of cholesterol in the blood by increasing the conversion of cholesterol into bile acids in the liver.

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How does nitroglycerin help angina?

Nitroglycerin helps angina by dilating coronary arterioles, which reduces resistance to blood flow and increases blood supply to the ischemic heart tissue.

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How do beta-blockers reduce angina?

Beta-blockers reduce angina by decreasing myocardial oxygen demand, allowing the heart to work less and consume less oxygen.

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What is the main concern with long-term use of nitroglycerin patches?

Continuous use of long-acting nitroglycerin formulations can lead to a decrease in their vasodilator effects over time. This is known as tolerance.

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What is hypertension?

Hypertension is a condition characterized by consistently high blood pressure.

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What is angina?

Angina is a type of chest pain that occurs when the heart muscle doesn't get enough oxygen. This is often caused by narrowing of the coronary arteries.

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What is the significance of family history in cardiovascular disease?

A family history of cardiovascular disease increases the risk of developing hypertension and angina.

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What does "moderate hypertension and angina pectoris" mean?

Moderate hypertension is a blood pressure reading that is elevated but not yet severe. Angina pectoris is a type of chest pain caused by reduced blood flow to the heart.

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Study Notes

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Test your knowledge with this General Study Notes quiz. The questions cover a wide range of topics to assess your comprehension and recall abilities. Perfect for students looking to prepare for exams or reinforce their learning.

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