anti-hypertensive drugs Q1

as BP=CO*PVR. reduce PVR. reduce CO by -chronotropes/-inrotropes, and decrease blood volume.

converts angiotensin I to angiotensin II (play a role in increasing BP). breaks down pro-inflammatory bradykinin.

reduce peripheral resistance and cardiac load. and they are non- peptide (orally active drugs)

<p>ramipril, lisinopril. drug cough (bradykinin). angioedema (bradykinin). Hyperkalaemia (aldosterone inhibition). Teratogenic.</p> Signup and view all the answers

<p>they block angiotensin II type 1 receptors (AT1). they r alternatives to ACEIs (when patient resistant). similar adverse effects to ACEIs but (nor dry cough).</p> Signup and view all the answers

<p>losartan, candesartan.</p> Signup and view all the answers

<p>negative chrono and inotropic effect ( reduce contraction and rate in heart).</p> Signup and view all the answers

<p>vascular smooth muscle (constriction).</p> Signup and view all the answers

<p>decrease renin release &gt; decrease angiotensin.</p> Signup and view all the answers

<p>decrease cardiac output. transient increase in PVR. long-term decrease in PVR.</p> Signup and view all the answers