General Physiology: Neurons and Action Potential
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Questions and Answers

What condition must be met for another action potential to occur during the relative refractory period?

  • The neuron must repolarize completely first.
  • Any normal stimulus can initiate the action potential.
  • No stimulus can occur during this period.
  • The stimulus must be greater than the normal stimulus. (correct)
  • What is the approximate resting membrane potential for neurons?

  • -50mV
  • -90mV
  • -70mV (correct)
  • -100mV
  • What is the role of voltage-gated Na+ channels during the action potential?

  • They initiate depolarizing stimulus. (correct)
  • They help maintain the resting membrane potential.
  • They are primarily responsible for saltatory conduction.
  • They close during repolarization.
  • What best describes the absolute refractory period?

    <p>No action potential can occur, regardless of the stimulus strength. (A)</p> Signup and view all the answers

    Which statement describes saltatory conduction?

    <p>It involves the jumping of action potentials between nodes of Ranvier. (B)</p> Signup and view all the answers

    What primarily occurs in the frontal lobe of the cerebrum?

    <p>Voluntary motor control and higher intellectual processes (B)</p> Signup and view all the answers

    Which structure is primarily involved in the coordination of movements and receives input from proprioceptors?

    <p>Cerebellum (D)</p> Signup and view all the answers

    What type of matter is primarily found in the cerebral cortex?

    <p>Gray matter (B)</p> Signup and view all the answers

    Which part of the brain acts as a relay center for auditory information?

    <p>Inferior colliculi (D)</p> Signup and view all the answers

    What is the primary function of the medulla oblongata?

    <p>Control of autonomic functions like heart rate and breathing (C)</p> Signup and view all the answers

    Which lobe of the cerebrum is responsible for interpreting textures and shapes?

    <p>Parietal Lobe (B)</p> Signup and view all the answers

    What is the function of the basal nuclei?

    <p>Control subconscious contractions of skeletal muscles (B)</p> Signup and view all the answers

    Which structure is considered part of the emotional brain?

    <p>Cingulate gyrus (B)</p> Signup and view all the answers

    What is the role of the thalamus in the diencephalon?

    <p>Relaying sensory and motor signals between brain regions (C)</p> Signup and view all the answers

    What does the cingulate gyrus contribute to?

    <p>Emotional regulation and memory processing (A)</p> Signup and view all the answers

    Which component of the brainstem is involved in respiratory control?

    <p>Pons (B)</p> Signup and view all the answers

    What is the primary function of the occipital lobe?

    <p>Visual perception and coordination (D)</p> Signup and view all the answers

    Which structure is responsible for initiating and terminating movements?

    <p>Basal nuclei (A)</p> Signup and view all the answers

    What primary role does the hypothalamus serve among the brain's structures?

    <p>Regulation of circadian rhythms (A)</p> Signup and view all the answers

    What role do oligodendrocytes play in the central nervous system?

    <p>They form myelin sheaths around axons. (C)</p> Signup and view all the answers

    What distinguishes a multipolar neuron from other types?

    <p>It has many dendrites and an axon. (D)</p> Signup and view all the answers

    What is the primary function of sensory or afferent neurons?

    <p>They transmit impulses from receptors to the CNS. (A)</p> Signup and view all the answers

    Which supporting cell type regulates the external environment of neurons in the CNS?

    <p>Astrocytes (B)</p> Signup and view all the answers

    What is a key factor that can influence action potential propagation?

    <p>Axon diameter (B)</p> Signup and view all the answers

    Which of the following statements is true about resting membrane potential?

    <p>It is constant under resting conditions. (A)</p> Signup and view all the answers

    What type of neurons are responsible for connecting sensory and motor pathways?

    <p>Association neurons (B)</p> Signup and view all the answers

    What is the primary function of Schwann cells in the peripheral nervous system?

    <p>They form myelin sheaths around peripheral axons. (C)</p> Signup and view all the answers

    Which structures are primarily responsible for the conduction of impulses away from the neuron cell body?

    <p>Axons (C)</p> Signup and view all the answers

    Flashcards

    Neurons

    Specialized nerve cells responsible for transmitting electrical impulses throughout the body.

    Cell Body (Soma)

    The central part of the neuron containing the nucleus and other organelles.

    Dendrites

    Branch-like extensions that receive impulses from other neurons and transmit them toward the cell body.

    Axon

    A long, slender extension that carries impulses away from the cell body and towards other neurons, muscles, or glands.

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    Unipolar Neurons

    Have one single extension from the cell body that branches into an axon and a dendrite.

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    Bipolar Neurons

    Have two extensions from the cell body: one axon and one dendrite.

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    Multipolar Neurons

    Have multiple dendrites and one axon. The most common type of neuron in the human nervous system.

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    Sensory (Afferent) Neurons

    Carry sensory information from receptors (like skin, eyes, ears) to the central nervous system (CNS).

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    Motor (Efferent) Neurons

    Relay impulses from the CNS to effectors (muscles or glands) to initiate a response.

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    Association (Interneurons)

    Connect sensory and motor neurons within the CNS, allowing complex neural pathways and processing of information.

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    Supporting Cells (CNS)

    Specialised cells that support and protect neurons in the central nervous system (CNS).

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    Oligodendrocytes

    Produce myelin sheaths around CNS axons, which speeds up signal transmission.

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    Microglia

    Immune cells that engulf and destroy foreign materials and debris in the brain and spinal cord.

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    Astrocytes

    Star-shaped cells that regulate the chemical environment around neurons and provide structural support.

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    Ependymal Cells

    Line the ventricles of the brain and the central canal of the spinal cord, producing cerebrospinal fluid.

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    Supporting Cells (PNS)

    Specialised cells that support and protect neurons in the peripheral nervous system (PNS).

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    Schwann Cells

    Form myelin sheaths around axons in the PNS, increasing signal transmission speed.

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    Satellite Cells

    Support the cell bodies of neurons located in ganglia of the PNS.

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    Central Nervous System (CNS)

    The brain and spinal cord, which control and coordinate all bodily functions.

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    Peripheral Nervous System (PNS)

    The network of nerves outside the CNS that connects it to the rest of the body.

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    Nerve

    A bundle of axons outside the CNS, typically containing both sensory and motor fibers.

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    Ganglion

    A collection of neuron cell bodies located outside the CNS.

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    Nucleus

    A collection of neuron cell bodies located within the CNS. 'Ganglia' but in the CNS.

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    Tract

    A bundle of axons within the CNS that interconnect different brain regions.

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    Resting Membrane Potential

    The electrical potential difference across the cell membrane of a neuron when it is not transmitting an impulse.

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    Action Potential

    A rapid change in membrane potential that travels down the axon of a neuron, transmitting a signal.

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    Myelination

    The degree of myelination (fatty sheath) around an axon affects how fast an impulse travels.

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    Axon Diameter

    Larger diameter axons conduct impulses faster than thinner axons.

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    Temperature

    Temperature influences the speed of action potential propagation.

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    Absolute Refractory Period

    A period during which a neuron cannot fire another action potential, regardless of the strength of the stimulus.

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    Relative Refractory Period

    A period during which a neuron can fire another action potential, but only with a stronger-than-normal stimulus.

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    Study Notes

    Neurons

    • Neurons are specialized nerve cells responsible for transmitting impulses.
    • Cell body (soma) contains the nucleus and is the central part of the neuron.
    • Neurons have two processes:
      • Dendrites, which carry impulses toward the soma.
      • Axons, which carry impulses away from the soma.

    Types of Neurons

    • Unipolar: One extension from the cell body.
    • Bipolar: Two extensions from the cell body.
    • Multipolar: Multiple dendrites and one axon.

    Neuron Functions

    • Sensory (afferent): Transmit impulses from receptors to the CNS.
    • Motor (efferent): Relay impulses from the CNS to effectors (muscles or glands).
    • Association (interneurons): Connect sensory and motor neurons.

    Supporting Cells (CNS)

    • Oligodendrocytes: Form myelin sheaths around CNS axons.
    • Microglia: Migrate to phagocytose foreign materials.
    • Astrocytes: Regulate the external environment of neurons in the CNS.
    • Ependymal cells: Line brain ventricles and the spinal cord's central canal.

    Supporting Cells (PNS)

    • Schwann cells: Form myelin sheaths around peripheral axons.
    • Satellite cells: Support neuron cell bodies within ganglia of the PNS.

    Nervous System Structure

    • CNS (Central Nervous System): Comprises the brain and spinal cord.
    • PNS (Peripheral Nervous System): Includes somatic (motor sensory) and autonomic (involuntary) nervous systems.

    Terminologies

    • Nerve: Bundle of axons in the PNS containing sensory and motor fibers.
    • Ganglion: Grouping of neuron cell bodies outside the CNS.
    • Nucleus: Grouping of neuron cell bodies within the CNS.
    • Tract: Grouping of axons that interconnect CNS regions.

    Resting Membrane Potential

    • A constant membrane potential in excitable and non-excitable cells when at rest.
    • Neurons typically have a resting membrane potential of -70mV.
    • The interior of the cell is negatively charged compared to the outside.

    Action Potential

    • Involves rapid changes in membrane potential (approximately 100mV).
    • Generated by depolarization of excitable membranes due to voltage-gated Na+ channels.
    • Involves phases of depolarization, repolarization, and hyperpolarization.

    Propagation Factors

    • Degree of myelination affects impulse transmission speed.
    • Larger axon diameters enhance conduction velocities.
    • Temperature influences action potential propagation.

    Refractory Periods

    • Absolute Refractory Period: No action potential can occur during this time regardless of stimulus.
    • Relative Refractory Period: A stronger-than-normal stimulus can initiate a new action potential.

    Central Nervous System Organization

    • Cerebrum: The largest brain part (80% of brain mass) with lobes controlling various functions (voluntary movement, personality, speech).
    • Cerebral Cortex:
      • Contains sensory, motor, and association areas.
      • Gray matter consists of cellular bodies, while white matter includes axon tracts.

    Lobes of the Cerebrum

    • Frontal Lobe: Involved in voluntary motor control, personality, and intellect.
    • Parietal Lobe: Processes somatosensory information and language.
    • Temporal Lobe: Handles auditory information and memory.
    • Occipital Lobe: Focuses on visual processing and perception.

    Limbic System

    • Known as the "emotional brain," it plays a key role in emotions and memory.
    • Key components include the cingulate gyrus, amygdala, hippocampus, and septal nuclei.

    Diencephalon

    • Central core of the brain housing sensory and motor processing nuclei.
    • Includes thalamus (sensory relay), hypothalamus (homeostasis), and epithalamus (includes pineal gland).

    Brainstem Regions

    • Midbrain: Contains nuclei for visual and auditory reflexes.
    • Pons: Relays signals between different brain regions and assists in regulating respiration.
    • Medulla Oblongata: Controls autonomic functions like heart rate and respiration, and houses vital centers.

    Cerebellum

    • Located at the back of the brain, involved in coordination and balance through input from proprioceptors.

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    Description

    This quiz covers fundamental concepts of neurons and action potentials, focusing on their role in the central nervous system. It explores how neurons stimulate or inhibit muscle contractions and affect gland activities. Enhance your understanding of neurophysiology and its critical functions in the body.

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