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General Patterns of Viral Infection

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What is the main difference between persistent-latent and persistent-asymptomatic viral infections?

Continuous production of virus particles in persistent-asymptomatic infections

How is an acute infection different from a persistent-pathogenic infection?

Years separating primary infection and fatal symptoms in persistent-pathogenic infections

Which type of infection involves continuous virus production for the life of the host?

Persistent-asymptomatic infection

What is one characteristic of the incubation period of a viral infection?

<p>Replication of viral genomes during this period</p> Signup and view all the answers

In which type of infection might reactivation be stimulated throughout the host's life?

<p>Persistent-latent infection</p> Signup and view all the answers

Which viral infection pattern involves periodic acute infections followed by phases with little or no detection of viral particles?

<p>Persistent-latent infection</p> Signup and view all the answers

What is the term used to describe the damage caused by the host's immune response to infection?

<p>Immunopathology</p> Signup and view all the answers

Which type of cells experience a crash in AIDS due to high viral titres?

<p>CD4+ T cells</p> Signup and view all the answers

What are some of the clinical signs of a viral disease as mentioned in the text?

<p>Fever, aches, tissue damage, nausea</p> Signup and view all the answers

How many serotypes of dengue virus are mentioned in the text?

<p>4</p> Signup and view all the answers

What is a characteristic feature regarding antibodies and dengue virus infection according to the text?

<p>Antibodies to one serotype do not efficiently protect against infection by another</p> Signup and view all the answers

What is a characteristic of Latency-associated transcripts (LATs) of HSV-1 during latent infection?

<p>Only a single transcription unit is expressed</p> Signup and view all the answers

Which statement is true regarding the behavior of persistently infected mice with Lymphocytic Choriomeningitis Virus?

<p>They are not as 'smart' as their uninfected peers</p> Signup and view all the answers

What happens during the acute phase of HIV infection?

<p>Rapid decline in CD4+ T cells and high viremia</p> Signup and view all the answers

In what phase does HIV infection typically last 5-10 years without treatment?

<p>Asymptomatic phase</p> Signup and view all the answers

Which virus is associated with persistent - asymptomatic infection that can affect virtually all tissues?

<p>HIV Virus</p> Signup and view all the answers

What consequence does introducing Lymphocytic Choriomeningitis Virus later in life have on mice?

<p>Causes encephalitis and edema leading to death</p> Signup and view all the answers

Which type of viral infection may be characterized by the persistent presence of the viral genome within the infected cell?

<p>Persistent-Latent infection</p> Signup and view all the answers

Herpesviruses are enveloped viruses with which type of genome?

<p>dsDNA</p> Signup and view all the answers

Which viral gene products may block the presentation of viral peptides within MHC I complexes?

<p>Viral gene products</p> Signup and view all the answers

Which viral gene products may promote the reproduction of the virus in latent infections?

<p>Gene products synthesized in small quantities</p> Signup and view all the answers

Which type of infection may establish latency in sensory ganglia?

<p>Herpesviruses</p> Signup and view all the answers

Which viral gene products may interfere with MHC I biogenesis and transport to the cell surface?

<p>Viral gene products</p> Signup and view all the answers

What is the primary site of HSV-1 infection?

<p>Epithelial cells</p> Signup and view all the answers

What is the state of the virus in sensory neurons after the initial infection?

<p>In a latent state</p> Signup and view all the answers

What can reactivate the latent HSV-1 virus?

<p>Factors such as bacterial infection, hormonal changes, and environmental stress</p> Signup and view all the answers

What happens to the epithelial cells during a reactivation of HSV-1 infection?

<p>They undergo apoptosis</p> Signup and view all the answers

What is the role of Latency-Associated Transcript (LAT) in HSV-1 infection?

<p>It suppresses apoptosis in neurons</p> Signup and view all the answers

How does HSV-1 reactivate and cause recurrent infection?

<p>By traveling down the axons of sensory neurons and re-infecting epithelial tissues</p> Signup and view all the answers

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