General Pathology Week 13: Vascular Maladies

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12 Questions

What is the principal mechanism of vascular disease characterized by narrowing or complete obstruction of vessel lumina?

Atherosclerosis

In blood vessels, which layer primarily consists of smooth muscle cells and extracellular matrix (ECM)?

Media

Which type of blood vessel is mainly affected by atherosclerosis?

Large muscular arteries

What is the function of large elastic arteries such as the aorta and pulmonary arteries?

Storing energy during systole and recoil during diastole

What is the predominant structure of medium-sized muscular arteries like the coronary and renal arteries?

Smooth muscle cells

Which blood vessels play a key role in regulating blood flow resistance and have a significant impact on blood pressure due to diameter changes?

Arterioles

What is the primary function of capillaries in the circulatory system?

Facilitating rapid exchange of diffusible substances between blood and tissue

What are veins adapted for due to their larger diameters, lumina, and thinner walls compared to arteries?

Facilitating rapid exchange of diffusible substances between blood and tissue

What separates the intima from the media in blood vessel walls?

Internal elastic lamina

What type of vessels receive nutrients from vasa vasorum in the adventitia?

Large and medium-sized vessels

What is the most common mechanism leading to weakening of vessel walls in vascular diseases?

Atherosclerosis

What causes selective involvement of vessels of specific calibers in vasculitis?

Inflammation and immune response

Test your understanding of causes and implications of vascular maladies in medicine, including narrowing, obstruction, and weakening of blood vessels. Explore the central importance of vascular diseases and their impact on arterial and venous systems.

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