General Pathology Overview
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What is the primary focus of cytopathology?

  • Detecting micro-organisms in body fluids.
  • Analyzing blood components for health assessment.
  • Studying abnormal cells to determine disease type. (correct)
  • Examining tissue samples under a microscope.

Which technique is NOT typically associated with anatomic pathology?

  • Flow-cytometry
  • Clinical Biochemistry (correct)
  • Electron microscopy
  • Light Microscopy

What staining technique is used to highlight nuclear chromatin and cytoplasmic proteins?

  • Haematoxylin and Eosin stain (H&E) (correct)
  • Molecular pathology stain
  • Reticulin stain
  • Immunohistochemistry

In which discipline are chromosomal abnormalities detected?

<p>Cytogenetics (B)</p> Signup and view all the answers

What is the primary role of toxicology in pathology?

<p>Investigating effects of known or alleged poisons. (A)</p> Signup and view all the answers

What does reticulin stain demonstrate in pathology?

<p>Tumor pathology features (B)</p> Signup and view all the answers

What is the primary focus of systemic pathology?

<p>Studying diseases affecting specific organs (B)</p> Signup and view all the answers

Which aspect of pathology involves the study of structural, biochemical, and functional changes at the cellular and tissue level?

<p>General pathology (C)</p> Signup and view all the answers

What is the role of clinical pathology in diagnosing diseases?

<p>Evaluating laboratory tests and body fluid analysis (A)</p> Signup and view all the answers

Which of the following correctly defines a symptom in the context of pathology?

<p>A complaint or experience indicating disease presence (A)</p> Signup and view all the answers

What does molecular pathology primarily focus on?

<p>Analyzing the genetic basis of diseases (B)</p> Signup and view all the answers

In clinical pathology, which process is crucial for accurate patient evaluation?

<p>Collecting and analyzing information systematically (A)</p> Signup and view all the answers

Which component is not a vital sign measured during a clinical assessment?

<p>Body mass index (A)</p> Signup and view all the answers

What does the term 'pathognomonic features' refer to?

<p>Disease-specific and distinctive features (C)</p> Signup and view all the answers

What does the term 'etiology' denote in pathology?

<p>The specific cause of the disease (C)</p> Signup and view all the answers

Which of the following best describes gross pathology?

<p>Macroscopic disease manifestations in various body parts (A)</p> Signup and view all the answers

What is the primary application of polymerase chain reaction (PCR) in pathology?

<p>Amplifying minute quantities of nucleic acids (D)</p> Signup and view all the answers

Which process involves studying visible changes in tissues and organs?

<p>Morphology (A)</p> Signup and view all the answers

What is assessed alongside vital signs prior to patient management?

<p>Drug hypersensitivity and medical history (C)</p> Signup and view all the answers

What are the two main subdivisions of histopathology?

<p>Surgical pathology and Experimental pathology (B)</p> Signup and view all the answers

Which of the following types of biopsy removes an entire lump?

<p>Excisional biopsy (D)</p> Signup and view all the answers

What is the main purpose of experimental pathology?

<p>To observe disease changes in animal models (A)</p> Signup and view all the answers

Which method of biopsy uses a wide needle to obtain tissue samples?

<p>Core biopsy (A)</p> Signup and view all the answers

Which of the following is a factor associated with acquired causes of diseases?

<p>Nutritional deficiency diseases (B)</p> Signup and view all the answers

What does Oral and Maxillofacial Pathology (OMFP) specialize in?

<p>Diseases of the oral cavity and related structures (C)</p> Signup and view all the answers

Which of the following is characterized as an idiopathic cause of disease?

<p>Unknown cause (A)</p> Signup and view all the answers

What type of injury is most likely associated with chemical agents?

<p>Chemical and drug injury (C)</p> Signup and view all the answers

Which of the following factors is NOT considered an acquired cause of disease?

<p>Genetic defects (C)</p> Signup and view all the answers

What type of pathology involves performing autopsy at postmortem?

<p>Forensic pathology (C)</p> Signup and view all the answers

Flashcards

Pathology

The study of the nature, causes, mechanisms, and consequences of diseases.

General Pathology

Focuses on the changes and responses at the cellular and tissue level related to the causes of diseases.

Systemic Pathology

Studies diseases that affect specific organs, considering their causes, mechanisms, appearance, and outcomes.

Clinical Pathology

Involves examining a patient's illness through clinical approaches, analyzing the disease based on specific methods and tests.

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Symptom

An individual's description of what they're experiencing, potentially suggesting the presence of a disease or condition.

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Clinical Approach

A systematic process where clinicians or pathologists gather information, analyze tests, and make diagnoses based on the patient's evaluation.

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Sign

Objective and observable indication detected during a physical examination or diagnostic procedure.

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Vital Signs

Measuring body temperature, heart rate, respiratory rate, and blood pressure.

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Pathognomonic Features

Disease-specific and distinctive features that clearly indicate a particular condition.

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Lesion

An area of abnormal tissue commonly affected by a disease or causative agent.

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Syndrome

A set of symptoms or conditions that occur together.

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Pathogenesis

The changes in the structure or function of an organism at the gross/clinical level.

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Morphology

The study of the changes in the gross (visible) or microscopic appearance of structural alterations in cells, tissues, and organs.

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What is Experimental Pathology?

The branch of pathology that studies the effects of experimental manipulations on animal models or cell cultures, helping understand human diseases.

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What is Pathology?

The scientific study of disease, examining the causes, mechanisms, and consequences of disease processes.

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What is Biopsy?

A microscopic examination of tissue samples obtained from a living body to diagnose or monitor disease.

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What is an Incisional Biopsy?

A type of biopsy where only a portion of the suspicious tissue is removed for examination.

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What is an Excisional Biopsy?

A biopsy technique that involves removing the entire lump or suspicious area.

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What is a Needle Biopsy?

A biopsy technique where a sample of tissue or fluid is removed using a needle.

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What is a Core Biopsy?

A type of needle biopsy where a wide needle is used to collect a core of tissue.

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What is a Fine-Needle Aspiration Biopsy?

A type of needle biopsy where a thin needle is used to obtain a sample by aspiration.

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What is Oral and Maxillofacial Pathology (OMFP)?

The branch of pathology that focuses on diseases affecting the mouth, jaws, and associated structures.

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What are Congenital/Genetic Causes of Diseases?

A condition present at birth, caused by genetic or developmental errors.

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Histopathology

Examining tissue under a microscope to identify disease.

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Cytopathology

Examining individual cells to determine disease.

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Hematology

The microscopic study of blood components.

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Clinical Biochemistry

Analyzing the chemical composition of blood and other fluids to detect disease.

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Microbiology

Identifying disease-causing microorganisms using various techniques.

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Cytogenetics

Detecting chromosomal abnormalities within cells.

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Study Notes

General Pathology: Introduction

  • Pathology is the scientific study of diseases.
  • Pathology links scientific principles to medicine.
  • It is crucial for diagnosis, prognosis, and treatment advice.
  • Pathology examines disease cause, progression, structural/functional changes, and natural history.

General Pathology (Basic Pathology)

  • Studies cellular and tissue level changes linked to disease causes.
  • Focuses on biochemical and structural changes within cells and tissues.

Systemic Pathology

  • Studies diseases affecting specific organs.
  • Investigates etiology, pathogenesis, morphology, clinical features, and consequences of diseases within organs.

Clinical Pathology

  • Focuses on clinical level investigation of illness symptoms and signs.
  • Includes patient medical history and clinical evaluation.
  • Uses diagnostic procedures like systematic clinical examination, tests on body fluids (blood, urine, CSF), and investigations.
  • Aims at accurate diagnosis and treatment plans.

Causes of Diseases

  • Diseases are grouped by congenital/genetic (inherited), acquired causes (trauma, infections), nutritional/environmental factors (chemical, physical), aging, and neoplastic factors (cancer).

Methods in Pathology

  • Histopathology: Examination of tissues under a microscope.
  • Cytology: Examination of cells.
  • Hematology: Examination of blood.
  • Clinical Biochemistry: Examination of blood and body fluids for chemical components.
  • Microbiology: Examination for infectious microorganisms.
  • Immunohistochemistry/immunofluorescence: Identification of proteins and cell markers.
  • Cytogenetics: Examination of cell chromosomes.
  • Forensic pathology/autopsy: Examinations for cause of death and medico-legal issues.
  • Toxicology: Identifying and studying the effects of poisons.

Techniques in Pathology

  • Anatomic pathology: Studies gross appearance of organs, microscopic examination of tissues (light microscopy ,immunohistochemistry, electron microscopy).
  • Special stains: These enhance visualization of specific structures or components (e.g., H&E, reticulin, PAS, Giemsa, Perl's).
  • Electron microscopy (EM): Detailed examination of cellular structures (organelles) to diagnose disorders and detect viruses.
  • Application of EM in diagnostic pathology: Commonly in renal biopsies, evaluating tumor development, and studying skin disorders.
  • Forensic Pathology/Autopsy: Examines a dead body to determine cause of death. Includes a post-mortem examination.

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General Pathology Lecture 2 PDF

Description

Explore the fundamental concepts of general pathology, including the scientific study of diseases and their implications in medicine. This quiz covers cellular changes, systemic pathology, and clinical evaluation processes essential for diagnosis and treatment. Test your understanding of both basic and systemic pathology principles.

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