General Biology 1: Introduction to Genetics
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Questions and Answers

What does the term 'genotype' refer to?

  • The expression of a specific trait
  • The process of gamete formation
  • The total set of alleles an individual contains (correct)
  • The physical appearance of an individual

What is the genotype of the F1 generation when one true-breeding purple and one true-breeding white plant are crossed?

  • PP
  • Pp (correct)
  • pp
  • Pp and pp

What does Mendel's Law of Segregation imply about the inheritance of alleles?

  • All offspring inherit both alleles from one parent
  • Alleles are passed on together without separation
  • Genes segregate equally into gametes (correct)
  • One allele is always dominant over another

Which of the following describes the possible gametes produced by a true-breeding purple parent?

<p>P only (C)</p> Signup and view all the answers

According to Mendel's Law of Independent Assortment, what is true about genes on different chromosomes?

<p>Every possible combination of alleles is equally likely (B)</p> Signup and view all the answers

In a Punnett square analysis of true-breeding parents, what types of gametes do they produce?

<p>Only one type of gamete each (A)</p> Signup and view all the answers

What phenotype will a plant with the genotype pp exhibit?

<p>White (C)</p> Signup and view all the answers

In the analysis of Mendel's cross, how many different phenotypes can F2 offspring display?

<p>Three (C)</p> Signup and view all the answers

What is indicated by the presence of a dominant purple allele in a cross between a purple and a white flower?

<p>There is a chance of white offspring being produced (C)</p> Signup and view all the answers

In the context of Mendelian genetics, what does the term 'true-breeding' imply?

<p>Organisms consistently produce offspring with the same phenotype (B)</p> Signup and view all the answers

What is the term for the offspring produced from the cross of two true-breeding parents?

<p>F1 generation (A)</p> Signup and view all the answers

Which of the following correctly describes gametes produced by true-breeding parents in Mendelian crosses?

<p>Homogeneous in genotype (B)</p> Signup and view all the answers

Which genotype represents a homozygous dominant organism in Mendelian genetics?

<p>PP (D)</p> Signup and view all the answers

How does the principle of independent assortment affect offspring traits?

<p>Alleles for different traits assort independently into gametes (B)</p> Signup and view all the answers

How do true-breeding parents in Mendel's experiments contribute to the gametes?

<p>They produce only one type of gamete. (B)</p> Signup and view all the answers

What is the main purpose of a test cross?

<p>To identify whether an individual is homozygous or heterozygous (C)</p> Signup and view all the answers

What is the appearance of all F1 generation offspring from a purple and a white true-breeding parent cross?

<p>All purple flowers (C)</p> Signup and view all the answers

In a test cross involving a purple-flowered pea plant, what are the possible genotypes of the plant being tested?

<p>PP or Pp (A)</p> Signup and view all the answers

What can be concluded if all offspring from a test cross produce the recessive phenotype?

<p>The original plant is homozygous dominant. (C)</p> Signup and view all the answers

If a purple-flowered pea plant (Pp) is crossed with a homozygous recessive plant (pp), what ratio of phenotypes would be expected?

<p>1:1 (D)</p> Signup and view all the answers

Which of the following best describes the term 'homozygous recessive'?

<p>An individual with two recessive alleles. (A)</p> Signup and view all the answers

What observable trait is caused by the dominant allele in pea plants?

<p>Purple flowers (A)</p> Signup and view all the answers

Which of the following statements about Punnett squares is true?

<p>They are used to determine genotype ratios from genetic crosses. (B)</p> Signup and view all the answers

If a homozygous purple-flowered pea plant is crossed with a homozygous white-flowered pea plant, what will be the phenotype of the offspring?

<p>All purple flowers (B)</p> Signup and view all the answers

What is the purpose of a test cross in genetics?

<p>To identify the genotype of an organism with a dominant phenotype. (D)</p> Signup and view all the answers

In a monohybrid cross, what is being studied?

<p>Only one variation of a single trait. (C)</p> Signup and view all the answers

Which of the following best describes a dihybrid cross?

<p>It examines two traits inherited independently from two true-breeding parents. (B)</p> Signup and view all the answers

What phenotype does the F1 generation of a dihybrid cross display?

<p>Only dominant traits for each individual trait. (D)</p> Signup and view all the answers

What is indicated by the notation RR YY in genetics?

<p>It indicates true-breeding individuals for two dominant traits. (B)</p> Signup and view all the answers

How can you differentiate between homozygous and heterozygous genotypes?

<p>By using a Punnett square for a test cross. (B)</p> Signup and view all the answers

What does a homozygous genotype mean in the context of Punnett squares?

<p>It contains two identical alleles for a given trait. (B)</p> Signup and view all the answers

Which trait combination represents recessive phenotypes in a dihybrid cross?

<p>rr yy (B)</p> Signup and view all the answers

What was one reason Mendel chose to study garden peas for his experiments?

<p>Many pea varieties were available and they can self-fertilize. (D)</p> Signup and view all the answers

Which of the following best describes Mendel's hypothesis regarding his experiments?

<p>Traits are inherited independently and randomly. (A)</p> Signup and view all the answers

In a mono- or dihybrid cross, what is the significance of identifying the parental generation?

<p>It helps in calculating the probabilities of trait inheritance. (A)</p> Signup and view all the answers

What is a test cross and why is it important?

<p>A test cross involves a dominant phenotype and a homozygous recessive, revealing genotype. (D)</p> Signup and view all the answers

Which figure from Mendel’s work is essential for understanding the outcomes of genetic crosses?

<p>Figure 12.8, which illustrates Punnett squares. (A)</p> Signup and view all the answers

Which of the following statements accurately reflects Mendel’s principle of segregation?

<p>Each individual has two alleles for each trait, which segregate during gamete formation. (D)</p> Signup and view all the answers

Why are Punnett squares useful in Mendelian genetics?

<p>They predict the genotypes of offspring from known parents. (D)</p> Signup and view all the answers

What is the primary advantage of using a dihybrid cross in Mendelian genetics?

<p>It allows for the observation of interactions between two different traits. (A)</p> Signup and view all the answers

What is the expected phenotypic ratio in the F2 generation according to Mendel's findings?

<p>3:1 (C)</p> Signup and view all the answers

In Mendel's model, what term describes organisms with two identical alleles?

<p>Homozygous (C)</p> Signup and view all the answers

Which of the following statements best describes alleles in Mendel’s model?

<p>Alleles remain discrete and do not blend. (D)</p> Signup and view all the answers

What is the expected genotypic ratio resulting from a monohybrid cross according to Mendel's findings?

<p>1:2:1 (B)</p> Signup and view all the answers

What defines a dominant allele in Mendel's model?

<p>It is always expressed in the phenotype regardless of the presence of alleles. (A)</p> Signup and view all the answers

What ratio indicates the proportion of dominant to recessive traits in the F2 generation?

<p>3:1 (D)</p> Signup and view all the answers

What happens to a recessive trait in the presence of a dominant allele?

<p>It is masked and not expressed. (C)</p> Signup and view all the answers

What did Mendel conclude about the inheritance of traits?

<p>Traits are inherited in a numerical ratio. (D)</p> Signup and view all the answers

What is the probability of obtaining a green phenotype from a heterozygous pea plant in a cross?

<p>1/4 (D)</p> Signup and view all the answers

If two heterozygous pea plants are crossed, what is the expected probability that an offspring will be both round and green?

<p>3/16 (A)</p> Signup and view all the answers

What does the genotype 'yyRr' represent in terms of seed color and texture?

<p>Green and wrinkled seeds (B)</p> Signup and view all the answers

In a Punnett square analysis, if a pea plant with a genotype of 'YyRr' is crossed with another of the same genotype, what is the total number of possible genotypes for the offspring?

<p>16 (D)</p> Signup and view all the answers

What is the probability of an event that is certain to occur?

<p>1 (C)</p> Signup and view all the answers

If the probability of an event occurring is defined as q, what does (1 - q) represent?

<p>The probability of the event not occurring (B)</p> Signup and view all the answers

Which phenotype combination represents all combinations from crossing two heterozygous round and green pea plants?

<p>Round green, round yellow, wrinkled green, wrinkled yellow (D)</p> Signup and view all the answers

Which equation represents the addition of the probabilities of all possible outcomes of a dependent event?

<p>p + q = 1 (D)</p> Signup and view all the answers

For mutually independent events, how is the overall probability calculated?

<p>P = P1 × P2 × P3... (D)</p> Signup and view all the answers

What is the probability of rolling a specific number on a six-sided die?

<p>1/6 (B)</p> Signup and view all the answers

If an event has a probability of 0, what can be concluded about its occurrence?

<p>It is impossible to happen (A)</p> Signup and view all the answers

What does a probability of 0.5 indicate about an event's chances?

<p>The event has an equal chance of occurring or not occurring (D)</p> Signup and view all the answers

What is the probability of obtaining 'heads' when flipping a fair coin?

<p>1/2 (D)</p> Signup and view all the answers

What phenotype ratio is typically observed in the F2 generation of a dihybrid cross?

<p>9:3:3:1 (B)</p> Signup and view all the answers

Which statement best describes the principle of independent assortment?

<p>The alleles of different genes segregate independently during gamete formation. (C)</p> Signup and view all the answers

According to Law 2 of probability, if the probability of an event occurring is defined as q, what represents the probability that the event does not occur?

<p>P = 1 - q (D)</p> Signup and view all the answers

What is the significance of the dihybrid cross showing a phenotypic ratio of 9:3:3:1?

<p>It illustrates the law of independent assortment. (B)</p> Signup and view all the answers

Which aspect does not contribute to the probability calculations of multiple characters using the law of probability?

<p>Assuming events are completely unrelated. (A)</p> Signup and view all the answers

What occurs during metaphase I in meiosis that contributes to independent assortment?

<p>Homologous chromosomes align randomly at the equatorial plate. (D)</p> Signup and view all the answers

What would be the probability of a specific trait if it is certain to occur?

<p>1 (C)</p> Signup and view all the answers

Which of the following accurately reflects the approach to using a Punnett square for probability calculations?

<p>It provides an exact count of possible offspring genotypes. (D)</p> Signup and view all the answers

What is the probability of rolling either a 2 or a 6 on a standard six-sided die?

<p>1/3 (C)</p> Signup and view all the answers

What is the probability of rolling a 2 and a 6 when using two six-sided dice?

<p>1/36 (B)</p> Signup and view all the answers

When crossing two heterozygous plants (Pp), what is the probability of obtaining the heterozygous genotype Pp?

<p>1/2 (C)</p> Signup and view all the answers

What principle explains that the probability of independent events occurring together is the product of their individual probabilities?

<p>Multiplication Rule (C)</p> Signup and view all the answers

In a genetic cross between two heterozygous parents (Pp x Pp), what fraction of the offspring is expected to be homozygous recessive (pp)?

<p>1/4 (B)</p> Signup and view all the answers

If the probability of event P is 1/6 and the probability of event Q is 1/6, what is the probability of both events occurring if they are independent?

<p>1/36 (C)</p> Signup and view all the answers

When rolling a single six-sided die, what is the probability of not rolling a number higher than 4?

<p>4/6 (B)</p> Signup and view all the answers

What is the probability of obtaining a genotype of pp from a self-pollination of two heterozygous pea plants?

<p>1/4 (D)</p> Signup and view all the answers

What is the expected probability of rolling an even number (2, 4, or 6) on a single six-sided die?

<p>1/2 (B)</p> Signup and view all the answers

What genotype represents a plant that has both dominant traits for seed color and texture?

<p>YYRR (B)</p> Signup and view all the answers

In the context of a Punnett square, what does a genotype of Pp indicate?

<p>Heterozygous (B)</p> Signup and view all the answers

What is the expected phenotypic outcome when two heterozygous plants (YyRr) are crossed?

<p>1 round yellow, 1 round green, 1 wrinkled yellow, and 1 wrinkled green (C)</p> Signup and view all the answers

What is the combined probability of obtaining either a round and green seed or a wrinkled and yellow seed from a dihybrid cross?

<p>1/2 (D)</p> Signup and view all the answers

Which statement accurately reflects Mendel's law of independent assortment?

<p>Alleles segregate independently during gamete formation (C)</p> Signup and view all the answers

What is the significance of identifying the genotype of the parental generation in a genetic cross?

<p>It is needed to calculate offspring probabilities (C)</p> Signup and view all the answers

When two peas with the genotype YyRr are crossed, what fraction of the offspring will be expected to have green and wrinkled seeds?

<p>1/16 (C)</p> Signup and view all the answers

What does a dihybrid cross primarily investigate?

<p>Two separate traits simultaneously (C)</p> Signup and view all the answers

What is the significance of true-breeding parents in Mendel's experiments?

<p>They ensure consistent trait expression in offspring (B)</p> Signup and view all the answers

In a test cross, what is the primary goal?

<p>To determine the genotype of a dominant phenotype (D)</p> Signup and view all the answers

What is indicated by a phenotypic ratio observed in the F2 generation?

<p>The inheritance patterns of alleles (B)</p> Signup and view all the answers

How did Mendel's use of garden peas contribute to his findings in genetics?

<p>Their traits were easily observable and controlled (B)</p> Signup and view all the answers

What is the expected outcome when analyzing the F1 generation of a dihybrid cross?

<p>Only dominant phenotypes for each trait are expressed (D)</p> Signup and view all the answers

In genetic crosses, what is the role of a Punnett square?

<p>To predict possible offspring genotypes and phenotypes (A)</p> Signup and view all the answers

What is a characteristic feature of a monohybrid cross?

<p>It focuses on two variations of one trait (C)</p> Signup and view all the answers

What type of cells are gametes, and how many sets of chromosomes do they contain?

<p>Haploid, 1 set of chromosomes (A)</p> Signup and view all the answers

Which statement correctly describes the sex chromosomes in humans?

<p>Males are hemizygous due to non-homologous sex chromosomes. (D)</p> Signup and view all the answers

What genetic mechanism prevents females from expressing double the amount of X chromosome genes?

<p>Dosage compensation (C)</p> Signup and view all the answers

What is the function of the SRY gene in human development?

<p>To trigger masculinization of genitalia (A)</p> Signup and view all the answers

In terms of genetic variation, offspring result from what process involving parental genetic material?

<p>Meiosis (C)</p> Signup and view all the answers

How many pairs of homologous chromosomes do humans possess?

<p>23 pairs (B)</p> Signup and view all the answers

In birds, which sex is typically hemizygous for sex chromosomes?

<p>Females (D)</p> Signup and view all the answers

Why do female cells not produce double the amount of proteins from X-linked genes?

<p>Only one X chromosome is active. (D)</p> Signup and view all the answers

What is the purpose of amniocentesis in high-risk pregnancies?

<p>To extract amniotic fluid for fetal cell analysis (C)</p> Signup and view all the answers

Which condition is characterized by the presence of an extra X chromosome in males?

<p>Klinefelter syndrome (A)</p> Signup and view all the answers

Which symptom is NOT commonly associated with Turner syndrome?

<p>Increased fertility (A)</p> Signup and view all the answers

What characterizes individuals with triple X syndrome?

<p>Normal physical and mental appearance (B)</p> Signup and view all the answers

Which sex chromosome aneuploidy condition typically results in females with one fewer X chromosome?

<p>XO (B)</p> Signup and view all the answers

Which physical characteristic is associated with Jacob syndrome?

<p>Slightly taller and thinner (B)</p> Signup and view all the answers

Which of the following is a possible outcome of nondisjunction of sex chromosomes?

<p>Variations in sex chromosome count leading to aneuploidies (A)</p> Signup and view all the answers

Individuals with Klinefelter syndrome often exhibit which of the following conditions?

<p>Small testicles and infertility (B)</p> Signup and view all the answers

What does the presence of Barr bodies indicate in female cells?

<p>Inactivation of one X chromosome (A)</p> Signup and view all the answers

What is the typical phenotype representation in calico cats due to Barr bodies?

<p>Mosaic fur (B)</p> Signup and view all the answers

What was the dominant trait observed in the F1 progeny when Thomas Hunt Morgan crossed a white-eyed male fly with a red-eyed female fly?

<p>Red eyes (D)</p> Signup and view all the answers

How many X chromosomes are inactivated in female mammals?

<p>One X chromosome (A)</p> Signup and view all the answers

What unique pattern was observed in the F2 generation of Morgan's crosses involving the red-eyed and white-eyed fruit flies?

<p>Three red-eyed and one white-eyed fly, with white eyes only in males (C)</p> Signup and view all the answers

Who first discovered Barr bodies?

<p>Murray Barr (C)</p> Signup and view all the answers

What chromosomal composition do human females inherit?

<p>23 chromosomes from mothers and 23 from fathers (B)</p> Signup and view all the answers

Which of the following conclusions did Thomas Hunt Morgan reach regarding the gene for eye color in fruit flies?

<p>The eye color gene is sex-linked and resides on the X chromosome. (C)</p> Signup and view all the answers

What impact does X chromosome inactivation have on female traits?

<p>It creates variability in trait expression. (D)</p> Signup and view all the answers

What notation is used to represent a homozygous mutant genotype in Thomas Hunt Morgan's studies?

<p>-/- (C)</p> Signup and view all the answers

What type of inheritance pattern is shown by the fur colors in calico cats?

<p>X-linked inheritance (B)</p> Signup and view all the answers

Which scientist is credited with the chromosomal theory of inheritance that involved the pairing of similar chromosomes during meiosis?

<p>Walter Sutton (C)</p> Signup and view all the answers

What was the basis of Thomas Hunt Morgan's experiments with Drosophila melanogaster?

<p>Exploring sex-linkage through eye color variation. (C)</p> Signup and view all the answers

What is the structural characteristic of a Barr body?

<p>Highly condensed (D)</p> Signup and view all the answers

What was the significance of Morgan's testcross involving F1 female and white-eyed male flies?

<p>It demonstrated the dominance of red eyes over white eyes. (D)</p> Signup and view all the answers

What term describes all the cells in a multicellular organism that are not involved in reproduction?

<p>Somatic cells (A)</p> Signup and view all the answers

What is the likelihood that a sibling will be genetically identical to you, given 223 possible combinations of chromosome pairs?

<p>1 in 8,324,608 (B)</p> Signup and view all the answers

How do homologous chromosomes differ from sister chromatids during meiosis?

<p>Homologous chromosomes come from different parents. (D)</p> Signup and view all the answers

Why is red-green color blindness more common in males than females?

<p>Males have only one X chromosome, leading to unmasked recessive alleles. (B)</p> Signup and view all the answers

What does the term 'recombinant' refer to in the context of meiosis?

<p>A gamete that has undergone crossing over. (A)</p> Signup and view all the answers

Which of the following statements about crossing over is accurate?

<p>It leads to genetic variation among gametes. (B)</p> Signup and view all the answers

What is the significance of the X and Y chromosomes being non-homologous in males?

<p>It allows for the expression of recessive traits in males. (A)</p> Signup and view all the answers

What does aneuploidy refer to in genetics?

<p>An abnormal number of chromosomes (D)</p> Signup and view all the answers

Which factor influences the frequency of crossing over between two alleles?

<p>The physical distance between the alleles on the chromosome. (A)</p> Signup and view all the answers

Which statement about monosomic individuals is correct?

<p>They have lost one copy of an autosome. (C)</p> Signup and view all the answers

What is the primary effect of having two X chromosomes in females compared to males?

<p>Females are less likely to express recessive traits. (B)</p> Signup and view all the answers

What is one characteristic of trisomies involving chromosomes 13, 15, and 18?

<p>They typically do not survive past infancy. (C)</p> Signup and view all the answers

What correlation exists between maternal age and Down syndrome?

<p>Older mothers have a higher chance of having a child with Down syndrome. (D)</p> Signup and view all the answers

What is the main consequence of nondisjunction during meiosis?

<p>An incorrect number of chromosomes in gametes. (D)</p> Signup and view all the answers

What typically happens to monosomic individuals during development?

<p>They do not survive embryonic development. (C)</p> Signup and view all the answers

Which chromosome pair is referred to as the sex chromosomes?

<p>The 23rd pair (D)</p> Signup and view all the answers

What is an important factor when studying the occurrences of Down syndrome?

<p>Maternal age at conception. (B)</p> Signup and view all the answers

In a family pedigree, how are male individuals represented?

<p>Squares (B)</p> Signup and view all the answers

Which pattern of inheritance is associated with juvenile glaucoma?

<p>Dominant trait pedigree (B)</p> Signup and view all the answers

What type of dominance occurs when both alleles contribute to the phenotype equally?

<p>Codominance (B)</p> Signup and view all the answers

What is the condition called where the pigment melanin is not produced?

<p>Albinism (B)</p> Signup and view all the answers

Which pattern of inheritance allows for multiple alleles to exist for a single trait?

<p>Multiple alleles (B)</p> Signup and view all the answers

In pedigrees, what visual element indicates mating between two individuals?

<p>Horizontal line (A)</p> Signup and view all the answers

In a pedigree showing hemophilia, which group is more frequently affected?

<p>Males (D)</p> Signup and view all the answers

What term describes when one gene's expression is affected by another gene?

<p>Epistasis (A)</p> Signup and view all the answers

Why might not all offspring in a dominant trait pedigree exhibit the dominant disease?

<p>One parent is a heterozygote (A)</p> Signup and view all the answers

Which pattern of inheritance involves a single gene affecting multiple traits?

<p>Pleiotropy (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of a recessive trait pedigree?

<p>All offspring of affected parents are affected (A)</p> Signup and view all the answers

In a dominant trait pedigree, what does a heterozygous genotype indicate?

<p>The individual carries one mutated allele (A)</p> Signup and view all the answers

What does it mean if a trait is said to be influenced by the environment?

<p>Phenotype can change due to external factors. (A)</p> Signup and view all the answers

In which type of dominance is the phenotype of heterozygotes intermediate between the phenotypes of the two homozygotes?

<p>Incomplete dominance (B)</p> Signup and view all the answers

What type of trait is hemophilia categorized as?

<p>Sex-linked trait (B)</p> Signup and view all the answers

Which of the following statements about carrier individuals in a pedigree is true?

<p>Carriers can pass the trait to their offspring (D)</p> Signup and view all the answers

What is a characteristic of codominance in genetics?

<p>Both alleles contribute to the phenotype equally. (C)</p> Signup and view all the answers

Which of the following statements is NOT an assumption of Mendel's model of inheritance?

<p>There can be multiple phenotypes for a single gene. (B)</p> Signup and view all the answers

What occurs in incomplete dominance?

<p>The heterozygote displays a phenotype that is a mix of both homozygotes. (D)</p> Signup and view all the answers

Which example illustrates Mendel's model of complete dominance?

<p>Purple flowers completely masking the expression of white flowers. (D)</p> Signup and view all the answers

What role do alleles play in the ABO blood group system?

<p>They can showcase both dominant and recessive traits. (C)</p> Signup and view all the answers

Which statement about Mendel’s findings is true?

<p>Mendel's concepts laid the foundation for modern genetics. (C)</p> Signup and view all the answers

Why are Mendel's simple ratios not always observed in other traits?

<p>Many traits are controlled by multiple genes. (B), His model assumes a simplistic view of inheritance. (C)</p> Signup and view all the answers

What phenotype ratios arise when pink flowers (incomplete dominance) are self-crossed?

<p>1 red : 2 pink : 1 white (D)</p> Signup and view all the answers

What is one effect of the dominant frizzle gene in chickens?

<p>Causes feathers to curl outward (A)</p> Signup and view all the answers

How does epistasis affect phenotypic expression?

<p>It can suppress the expression of another gene (A)</p> Signup and view all the answers

In the example of Labrador dogs, which alleles determine the coat color?

<p>B and E (A)</p> Signup and view all the answers

What term describes alleles that exhibit simultaneous expression in a heterozygote's phenotype?

<p>Codominant (B)</p> Signup and view all the answers

What indicates an environmental influence on phenotype?

<p>Pigment production occurs only below 33°C (C)</p> Signup and view all the answers

Which statement about pleiotropy is correct?

<p>One gene affects multiple traits (A)</p> Signup and view all the answers

Which blood type is a universal recipient due to its compatibility with all other blood groups?

<p>Type AB (B)</p> Signup and view all the answers

What was observed in the F2 generation when two true-breeding corn varieties lacking anthocyanin were crossed?

<p>Produced both pigmented and colorless seeds (A)</p> Signup and view all the answers

What do the alleles IA and IB contribute to the ABO blood group system?

<p>They express both A and B antigens (B)</p> Signup and view all the answers

Which of the following traits did the frizzle gene affect in chickens?

<p>Feather direction (B)</p> Signup and view all the answers

What is a potential consequence for a person with type O blood receiving a blood transfusion from type A blood?

<p>Severe hemolytic reaction (A)</p> Signup and view all the answers

Which phenotype would be exhibited by a person with the genotype IAi?

<p>Type A blood (A)</p> Signup and view all the answers

What role does the 'E' allele play in the color of Labrador dogs?

<p>Allows pigment deposition to occur (C)</p> Signup and view all the answers

In terms of blood transfusion, what do antibodies present in the blood plasma target?

<p>Antigen sugars on blood cells (B)</p> Signup and view all the answers

What is defined as the phenomenon where multiple genes contribute to a single trait, resulting in continuous variation?

<p>Polygenic inheritance (C)</p> Signup and view all the answers

Which best describes the concept of pleiotropy?

<p>A single gene affecting multiple traits (C)</p> Signup and view all the answers

What characteristic is NOT true of Type O blood?

<p>Is a universal recipient (A)</p> Signup and view all the answers

In the ABO blood group system, which function do the IA and IB alleles serve in heterozygous individuals?

<p>They demonstrate codominance (C)</p> Signup and view all the answers

In the context of genetics, what distinguishes multiple alleles from polygenic inheritance?

<p>Multiple alleles involve more than two forms of a single gene (A)</p> Signup and view all the answers

What is an example of polygenic inheritance?

<p>Human eye color (C)</p> Signup and view all the answers

Which of the following statements about pleiotropy is true?

<p>A gene can influence multiple phenotypic traits (B)</p> Signup and view all the answers

How does the vestigial gene in Drosophila exemplify pleiotropy?

<p>It influences both wing development and reproductive traits (D)</p> Signup and view all the answers

Which of the following traits is NOT typically influenced by polygenic inheritance?

<p>Blood type (B)</p> Signup and view all the answers

Which inheritance pattern involves the interaction between multiple genes and environmental factors to affect phenotype?

<p>Polygenic inheritance (A)</p> Signup and view all the answers

Flashcards

Mendel's Principles

The fundamental laws of inheritance discovered by Gregor Mendel, explaining how traits are passed from parents to offspring. These principles include the Law of Segregation and the Law of Independent Assortment.

Monohybrid Cross

A genetic cross involving one trait, such as flower color, where each parent has different alleles for that trait.

Dihybrid Cross

A genetic cross involving two traits, such as seed shape and seed color, where each parent has different alleles for both traits.

Parental Generation (P)

The original parents used in a genetic cross, often denoted as P1 and P2.

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First Filial Generation (F1)

The offspring produced from the parental generation (P) in a genetic cross.

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Second Filial Generation (F2)

The offspring produced from the first filial generation (F1) in a genetic cross.

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Test Cross

A cross between an individual with an unknown genotype for a specific trait and a homozygous recessive individual for that trait. It helps determine the genotype of the unknown individual.

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Punnett Square

A diagram used to predict the possible genotypes and phenotypes of offspring in a genetic cross.

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F2 Generation

The second filial generation is the offspring resulting from the self-fertilization of F1 plants.

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3:1 Ratio

Mendel observed that in the F2 generation, the ratio of dominant traits to recessive traits was approximately 3:1. This means for every 3 plants expressing the dominant trait, there was 1 expressing the recessive trait.

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F3 Generation

The third filial generation is formed from the self-fertilization of F2 plants. It represents the 'great-grandchildren' of the original parents.

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1:2:1 Ratio

In the F3 generation, Mendel discovered a genetic ratio of 1:2:1. This meant that for every one true-breeding dominant plant, there were two not-true-breeding dominant plants, and one true-breeding recessive plant.

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Dominant Trait

A trait that is expressed in the offspring even when only one copy of the corresponding allele is present. It masks the recessive trait.

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Recessive Trait

A trait that is only expressed in the offspring when two copies of the corresponding allele are present. It is masked by the dominant trait.

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Allele

An alternative form of a gene. Each gene comes in two versions, so each parent gives their offspring one copy of each gene.

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Homozygous

Having two copies of the same allele for a particular gene. This means both copies are the same version.

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Genotype

The complete set of genes an individual possesses, representing the genetic makeup.

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Mendel's Law of Segregation

During gamete formation, pairs of alleles separate, so each gamete receives only one allele from each pair.

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Mendel's Law of Independent Assortment

Alleles for different genes separate independently during gamete formation, leading to various combinations of alleles.

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True-breeding parent

An organism that always produces offspring with the same trait when self-fertilized.

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What is a Punnett square?

A diagram used to predict the possible genotypes and phenotypes of offspring in a genetic cross.

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Dominant allele

An allele that masks the expression of another allele in a heterozygous individual.

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Recessive allele

An allele that is masked by a dominant allele in a heterozygous individual.

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Gamete

A reproductive cell (like a sperm or egg) containing only half the number of chromosomes of a normal cell.

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Heterozygous

Having two different alleles for a specific trait.

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Why use a test cross?

It helps determine whether an individual with a dominant phenotype is homozygous or heterozygous for a specific trait.

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Homozygous Recessive Individual

An individual carrying two copies of the recessive allele for a specific trait.

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Unknown Genotype

The genetic composition of an individual for a specific trait that is not readily known.

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Purple Flowered Pea Plant

A pea plant displaying purple flowers, a dominant trait.

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PP

Homozygous dominant genotype for purple flower color.

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Pp

Heterozygous genotype for purple flower color.

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What is a test cross?

A cross between an individual with an unknown genotype for a specific trait and a homozygous recessive individual for that trait. It helps determine the genotype of the unknown individual.

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True-breeding lines

Parental lines that consistently produce offspring with the same trait, if self-pollinated. They are homozygous for the specific trait.

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Dominant phenotype

The trait that is visible in an individual even if they have only one copy of the dominant allele.

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Probability of an Event

The chance of an event occurring, expressed as a number between 0 and 1 (or 0% and 100%). A probability of 0 means the event is impossible, while a probability of 1 means it's certain.

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Probability of an Event NOT Happening

The probability of an event not occurring is calculated by subtracting the probability of it happening from 1. So, if the chance of it happening is q, the chance of it not happening is (1 - q).

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Sum of Probabilities

When considering ALL possible outcomes of an event, the sum of their individual probabilities must always equal 1.

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Probability of Independent Events

The probability of multiple independent events happening together is found by multiplying the probabilities of EACH event happening.

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Probability of Getting Heads

When flipping a coin, there's an equal chance of getting heads or tails. Since there are two sides, the probability of getting heads is 1/2.

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Probability of Any Roll on a Die

With a six-sided die, each number has an equal chance of being rolled. Since there are six sides, the probability of any single roll is 1/6.

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Independent Assortment

The segregation of different allele pairs is independent. The alleles for different genes separate independently during gamete formation.

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Probability in Genetics

The likelihood of specific combinations of alleles occurring in offspring can be calculated using probability rules.

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Law of Probability (Genetics)

Used to calculate the probability of inheriting specific combinations of alleles.

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Calculating Probability (Genetics)

Involves determining the probability of each individual trait and then multiplying those probabilities together to get the combined probability.

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Phenotype Ratio (F2)

The ratio of different physical appearances resulting from a dihybrid cross in the second generation.

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Independent Segregation

During meiosis, homologous chromosomes separate independently of each other, leading to independent assortment of alleles.

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Probability of a single outcome

The chance of a specific event happening in a random process, calculated by dividing the number of favorable outcomes by the total number of possible outcomes.

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Probability of mutually exclusive events

The chance of one event happening OR another event happening, where both events cannot occur simultaneously. Calculated by adding the probabilities of each individual event.

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Probability of a specific genotype

The chance of an offspring inheriting a particular combination of alleles, calculated using a Punnett square.

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Heterozygous genotype

Having two different alleles for a specific gene, one from each parent.

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Homozygous genotype

Having two identical alleles for a specific gene, one from each parent.

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What is the probability of having the genotype Pp when crossing two heterozygotes Pp together?

The probability of having the genotype Pp when crossing two heterozygotes Pp together is 50% or 1/2. This is because there are two possibilities out of four where the offspring will have the Pp genotype.

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What is the probability of obtaining a green phenotype (yy) in a Punnett square?

The probability of getting a green phenotype (yy) depends on the genotypes of the parents. It's represented by the proportion of offspring with the yy genotype in the Punnett square.

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How to calculate the probability of a specific genotype?

To calculate the probability of a specific genotype, consider the probability of each allele being passed down and multiply those probabilities together.

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Independent Assortment in Genetics

Alleles for different genes separate independently during gamete formation, meaning the inheritance of one trait doesn't influence the inheritance of another.

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YyRr

The genotype representing a pea plant heterozygous for both seed color (Yy) and seed texture (Rr).

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Probability of Round and Green

The chance of a pea plant offspring having round (dominant) and green (recessive) seeds.

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Self-Pollination

A plant fertilizing itself, where pollen from the same plant reaches the ovule.

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What genotypes lead to purple flowers?

The possible combinations of alleles for flower color that result in a purple phenotype. These are PP ( homozygous dominant ) or Pp ( heterozygous ).

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Barr Body

A highly condensed, inactive X chromosome found in the nucleus of female cells, visible under a microscope.

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X Chromosome Inactivation

Random process where one of the two X chromosomes in female cells is inactivated, ensuring equal gene expression between males and females.

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Calico Cat Fur

The mosaic pattern of fur colors in female cats is due to random X chromosome inactivation, resulting in different fur colors depending on which X is active.

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Homologous Chromosomes

Pairs of chromosomes that carry genes for the same traits, one inherited from the mother and one from the father.

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Sister Chromatids

Two identical copies of a chromosome, joined together at the centromere, formed during DNA replication.

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Inheritance

The passing of traits from parents to offspring through genes.

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What are chromosomes?

Structures found in the nucleus of a cell that contain genetic material (DNA). They are organized into pairs, with one chromosome from each parent.

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How many chromosomes do humans have?

Humans have 23 pairs of chromosomes, totaling 46 chromosomes. One set of 23 comes from the father, and the other set of 23 comes from the mother.

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Crossing over

The exchange of genetic material between homologous chromosomes during meiosis.

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Recombinant

A gamete (sperm or egg cell) that carries a chromosome with a new combination of genes due to crossing over.

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Sex-linked disorders

Genetic conditions caused by mutated genes located on the X or Y chromosome.

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Red-green color blindness

A sex-linked disorder where individuals have difficulty distinguishing red and green colors.

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What is a gene?

A segment of DNA that codes for a specific trait, like eye color or hair color.

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What is an allele?

A variation of a gene. For example, there are alleles for brown eyes and blue eyes.

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Diploid Cell

A cell containing two complete sets of chromosomes. In humans, this means 46 chromosomes (2n = 46).

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Haploid Cell

A cell containing only one set of chromosomes. In humans, this means 23 chromosomes (n = 23).

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Sex Chromosomes

Chromosomes that determine an individual's sex (male or female). In humans, these are X and Y chromosomes.

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SRY Gene

A gene located on the Y chromosome that triggers the development of male characteristics in humans.

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Chromosomal Theory of Inheritance

The theory that genes are located on chromosomes and that these chromosomes are responsible for transmitting genetic information from one generation to the next.

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Sex Linkage

A pattern of inheritance where a gene is located on a sex chromosome, most commonly the X chromosome, and this leads to a different inheritance pattern in males and females.

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Thomas Hunt Morgan's Experiment

Morgan's experiments with fruit flies showed that a gene for eye color was located on the X chromosome, proving the concept of sex linkage.

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Mutant Fly

A fly with a genetic change, such as a different eye color, that was different from the common 'wild-type' flies.

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Wild-Type

The most common form of a trait or gene in a population, used as the standard comparison for mutants.

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The importance of test cross

Test crosses are used to determine the genotype of an individual with an unknown genotype by crossing it with a homozygous recessive individual.

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Amniocentesis

A prenatal test where a sample of amniotic fluid is taken from the pregnant woman's abdomen to analyze fetal cells for genetic disorders.

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Chorionic Villi Sampling

A less invasive prenatal test that analyzes fetal cells from the chorion, a part of the placenta.

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Triple X Females (XXX)

A genetic disorder resulting from an extra X chromosome, generally with few noticeable physical or mental differences.

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Klinefelter Syndrome (XXY)

A genetic disorder with an extra X chromosome in males, leading to small testicles, infertility, and lower testosterone levels.

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Turner Syndrome (XO)

A genetic disorder in females with a missing X chromosome, causing short stature, heart problems, and often infertility.

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Jacob Syndrome (XYY)

A genetic disorder in males with an extra Y chromosome, generally causing few unusual physical differences but may lead to learning and reading difficulties.

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Nondisjunction of Sex Chromosomes

An error during meiosis where chromosomes don't separate properly, leading to gametes with extra or missing sex chromosomes.

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What are the possible sex chromosome aneuploidies?

Possible sex chromosome aneuploidies include XXX, XXY, XO, OY, and XYY. These occur due to errors in meiosis.

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Nondisjunction

The failure of homologous chromosomes or sister chromatids to separate properly during meiosis.

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Aneuploidy

Having an abnormal number of chromosomes.

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Monosomy

Missing one copy of an autosome.

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Trisomy

Having an extra copy of an autosome.

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Down Syndrome

A genetic disorder caused by trisomy of chromosome 21, resulting in delayed skeletal and mental development.

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Autosome

Any chromosome that is not a sex chromosome. In humans, there are 22 pairs of autosomes.

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Genetic disorder

A disease or condition caused by an abnormality in an individual's genes or chromosomes.

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Complete Dominance

A type of inheritance where one allele completely masks the expression of another allele. The heterozygote phenotype looks identical to the homozygous dominant phenotype.

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Incomplete Dominance

A type of inheritance where the heterozygote phenotype is a blend of the two homozygous phenotypes. Neither allele is fully dominant.

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Codominance

A type of inheritance where both alleles are expressed fully in the heterozygote phenotype. Neither allele masks the other.

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ABO Blood Groups

An example of codominance where multiple alleles control blood type. Alleles IA and IB are codominant, producing distinct antigens, while allele i is recessive.

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What is a test cross used for?

A test cross is used to determine the unknown genotype of an individual displaying a dominant phenotype. It involves crossing the individual with a homozygous recessive individual.

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What is a Barr Body?

A highly condensed, inactive X chromosome found in the nucleus of female cells. It's a process called X chromosome inactivation.

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What is X chromosome inactivation?

A process where one of the two X chromosomes in a female cell is randomly inactivated. It ensures equal gene expression between males and females.

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What causes calico cat fur?

The mosaic pattern of fur colors in female cats is due to random X chromosome inactivation. Each cell expresses a different color based on which X chromosome is active.

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Pedigree Chart

A diagram that shows the inheritance of a trait over generations in a family. It uses symbols to represent individuals and their relationships.

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Dominant Trait Pedigree

A pedigree where the trait is expressed in individuals who have at least one copy of the dominant allele. Affected individuals appear in every generation.

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Recessive Trait Pedigree

A pedigree where the trait is only expressed in individuals who inherit two copies of the recessive allele. Affected individuals may skip generations.

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Sex-linked Trait Pedigree

A pedigree where the trait is determined by a gene on a sex chromosome (usually the X). Males are more likely to be affected than females.

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Hemophilia

A sex-linked recessive disorder where blood clotting is impaired, leading to excessive bleeding.

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Juvenile Glaucoma

A dominant genetic disorder causing degeneration of the optic nerve, leading to blindness.

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Albinism

A recessive genetic disorder where the body lacks melanin pigment, leading to pale skin, hair, and eyes.

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Carrier

An individual who carries one copy of a recessive allele but doesn't show the trait. They can pass the allele to their offspring.

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Pedigree

A family tree that shows the inheritance of traits across generations, using symbols to represent individuals and their relationships.

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Multiple Alleles

A gene with more than two possible alleles, leading to a wider range of phenotypes.

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Epistasis

A pattern of inheritance where the expression of one gene is influenced by another gene at a different locus.

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Pleiotropy

A single gene influences multiple, seemingly unrelated traits.

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Polygenic Inheritance

A trait controlled by multiple genes that contribute to a continuous range of phenotypes.

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Quantitative Traits

Traits controlled by multiple genes, showing continuous variation across a range. Example: Height, weight, skin color.

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Vestigial Gene

A gene involved in wing development in fruit flies. The recessive allele leads to short wings, and it also affects other traits (pleiotropy).

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What is the main difference between multiple alleles and polygenic inheritance?

Multiple alleles refer to different versions of the same gene, while polygenic inheritance involves multiple genes contributing to a single trait.

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Antigen

A substance, like a protein or sugar, that can trigger an immune response, leading to the production of antibodies.

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Antibody

A protein produced by the immune system that recognizes and binds to specific antigens, helping to neutralize or eliminate them.

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Blood Transfusion Compatibility

The ability of a donor's blood cells to be safely received by a recipient without causing an immune reaction.

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Universal Donor

Blood type O, which lacks antigens, can be donated to individuals with any blood type.

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Universal Receiver

Blood type AB, which has both A and B antigens, can receive blood from any blood type.

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Blood Type Incompatibility

An immune reaction that occurs when a recipient's blood contains antibodies that target the antigens on donor blood cells.

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Frizzle Gene

A dominant gene in chickens that causes outward-curling feathers, lower body temperature, and reduced egg production.

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Pigment Deposition

The process of depositing pigment in a specific location.

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Environmental Influence

Environmental factors affecting phenotypic expression.

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Himalayan Rabbits

Rabbits with dark fur at their extremities due to pigment production only at temperatures below 33°C.

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Siamese cats

Cats with dark fur at certain body parts due to temperature-sensitive pigment production.

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Coat Color in Himalayan Rabbits

The color pattern of Himalayan rabbits is determined by a combination of genes and the surrounding temperature.

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Study Notes

General Biology 1 - Fall 2024

  • Course: General Biology 1
  • Term: Fall 2024
  • Topic: Introduction to Genetics (Part 1)
  • Professor: Dr. Vincent Gagnon
  • Textbook: Raven, Biology, 13th edition, Chapter 12: Patterns of Inheritance

Mendel's Principles and Experiments

  • Mendel's experiments used garden peas due to their easily observable traits and ability for self-fertilization/cross-fertilization.
  • Numerous pea varieties with distinct characteristics were available.
  • Mendel's experiments followed a three-step process:
    • Creating true-breeding strains for different traits.
    • Cross-fertilizing true-breeding strains with contrasting traits. Mendel meticulously removed anthers from one parent plant to prevent self-pollination.
    • Allowing the hybrid offspring to self-fertilize for multiple generations and counting the traits of the offspring.
  • True-breeding strains consistently produce offspring with the same trait over multiple generations.
  • Mendel studied 7 different traits in pea plants: flower color, seed color, seed texture, pod color, pod shape, flower position, and plant height.
  • Each trait had identifiable contrasting variations.

Principles of Inheritance

  • Mendel's Law of Segregation - paired unit factors (genes) segregate equally into gametes, meaning offspring have an equal chance of inheriting either factor.
  • Mendel's Law of Independent Assortment - genes do not influence each other's transmission to gametes, and every possible allele combination is equally likely if the genes are on different chromosomes.

Monohybrid and Dihybrid Crosses

  • Monohybrid crosses examine the inheritance of a single trait.
    • Example: flower color
  • Dihybrid crosses examine the inheritance of two traits simultaneously.
    • Example: seed color and seed shape

F1 and F2 Generations

  • F1 generation: the first set of offspring from a cross of two true-breeding parents with contrasting traits. The F1 generation consistently showed one trait in common with one parent.
  • F2 generation: the second set of offspring from self-pollination of the F1 generation.
  • A 3:1 phenotypic ratio of dominant to recessive traits were apparent in the F2 generation.
  • The 3:1 phenotypic ratio reflects Mendel's law of segregation, with 3 showing the dominant trait and one showing the recessive trait.

Mendel's Five-element Model

  • Parents transmit discrete factors (genes) that code for traits.
  • Each individual receives one copy of a gene from each parent.
  • Not all gene copies are identical (alleles).
  • Alleles remain separate, without blending.
  • The presence of an allele does not guarantee its expression.
    • Dominant allele: Always expressed (represented with a capital letter, e.g., P).
    • Recessive allele: Only expressed when two copies are present (represented with a lowercase letter, e.g., p).

Testcross

  • Testing a suspected homozygous or heterozygous individual's genotype.
  • A testcross involves crossing the suspected individual with a homozygous recessive individual. This produces predictable offspring ratios, making it possible to determine if the mystery parent is homozygous or heterozygous.

Punnett Squares

  • Diagram used to predict possible genotypes of offspring from a genetic cross.
  • Helps visualize allele combinations and resulting phenotypes. Punnett squares show probabilities of specific genotypes and phenotypes from parental crosses.

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This quiz explores the fundamentals of genetics as introduced in General Biology 1. Focus on Mendel's principles and experiments using garden peas to understand patterns of inheritance. Gain insight into true-breeding strains and hybridization processes central to Mendelian genetics.

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