Gene Therapy vs

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Questions and Answers

Which of the following best describes gene therapy?

  • The use of genetic material to treat or prevent disease (correct)
  • The use of non-human cells to produce therapeutic proteins
  • The use of DNA or RNA to control dosing
  • The use of proteins to treat or prevent disease

What is one advantage of protein therapy over gene therapy?

  • Known concentration and dosing control (correct)
  • No contamination from infectious agents
  • Less immunogenic protein production
  • Continual protein production by patient's cells

Which condition can be treated through gene repair/correction in gene therapy?

  • Duchenne muscular dystrophy (correct)
  • Insulin production
  • Pancreatic islet beta cells
  • Hemophilia

What is one disadvantage of protein therapy in terms of toxicity?

<p>Short half-life and peak levels of toxicity (A)</p> Signup and view all the answers

What is one advantage of gene therapy over protein therapy in terms of immunogenicity?

<p>Protein produced by human cells, so less immunogenic (D)</p> Signup and view all the answers

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Study Notes

Gene Therapy Overview

  • Gene therapy involves modifying or manipulating genes to treat or prevent diseases.
  • It can entail replacing, inactivating, or introducing genes into cells to address genetic disorders.

Advantages of Protein Therapy

  • Protein therapy involves administering proteins directly to treat diseases.
  • One key advantage is immediate therapeutic effects, as proteins can act quickly in the body without requiring gene modification.

Conditions Treated by Gene Repair/Correction

  • Gene therapy can effectively treat conditions such as cystic fibrosis, hemophilia, and certain types of muscular dystrophy through gene repair or correction.

Disadvantages of Protein Therapy

  • Protein therapy may lead to toxicity due to high doses required or accumulation of proteins in tissues, which can trigger adverse reactions.

Advantages of Gene Therapy in Immunogenicity

  • Gene therapy offers potential long-term solutions with reduced risk of immune response compared to protein therapy, as it targets the genetic cause rather than introducing foreign proteins.

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