Gene Therapy vs
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Questions and Answers

Which of the following best describes gene therapy?

  • The use of genetic material to treat or prevent disease (correct)
  • The use of non-human cells to produce therapeutic proteins
  • The use of DNA or RNA to control dosing
  • The use of proteins to treat or prevent disease
  • What is one advantage of protein therapy over gene therapy?

  • Known concentration and dosing control (correct)
  • No contamination from infectious agents
  • Less immunogenic protein production
  • Continual protein production by patient's cells
  • Which condition can be treated through gene repair/correction in gene therapy?

  • Duchenne muscular dystrophy (correct)
  • Insulin production
  • Pancreatic islet beta cells
  • Hemophilia
  • What is one disadvantage of protein therapy in terms of toxicity?

    <p>Short half-life and peak levels of toxicity</p> Signup and view all the answers

    What is one advantage of gene therapy over protein therapy in terms of immunogenicity?

    <p>Protein produced by human cells, so less immunogenic</p> Signup and view all the answers

    Study Notes

    Gene Therapy Overview

    • Gene therapy involves modifying or manipulating genes to treat or prevent diseases.
    • It can entail replacing, inactivating, or introducing genes into cells to address genetic disorders.

    Advantages of Protein Therapy

    • Protein therapy involves administering proteins directly to treat diseases.
    • One key advantage is immediate therapeutic effects, as proteins can act quickly in the body without requiring gene modification.

    Conditions Treated by Gene Repair/Correction

    • Gene therapy can effectively treat conditions such as cystic fibrosis, hemophilia, and certain types of muscular dystrophy through gene repair or correction.

    Disadvantages of Protein Therapy

    • Protein therapy may lead to toxicity due to high doses required or accumulation of proteins in tissues, which can trigger adverse reactions.

    Advantages of Gene Therapy in Immunogenicity

    • Gene therapy offers potential long-term solutions with reduced risk of immune response compared to protein therapy, as it targets the genetic cause rather than introducing foreign proteins.

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    Description

    Test your knowledge on gene therapy and protein therapy with this quiz. Learn about the basics of gene therapy and its applications in disease treatment and prevention. Understand the differences between gene therapy and protein therapy, including factors such as dosing, degradation rate, toxicity, and sourcing.

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