30 Questions
What is the primary goal of gene therapy?
To replace a mutated gene that causes disease with a healthy copy of the gene
What is the current status of gene therapy?
It is still under study to ensure its safety and effectiveness
What is the role of viruses in gene therapy?
They are used to deliver new genes into cells
What type of diseases is gene therapy currently being tested for?
Diseases that have no other cures
What is the purpose of introducing a new gene into the body?
To make a beneficial protein to fight a disease
What is the function of the normal copy of the gene introduced through gene therapy?
To restore the function of a necessary protein
What is the primary role of collagenase in treating skin ulcers and burns?
Breaking and removing dead skin
What is the primary source of lytic enzymes?
Bacteriophage
What is the primary function of chitinase?
Hydrolyzing chitin
What is the primary factor influencing the immune response to non-viral DNA complexes?
Dose of the complex
What is the primary target of most antimicrobials?
Chitin
What is the effect of infection and inflammation on cytochrome P450 enzymes?
Reduced expression and function
What is the primary application of lysozyme?
Treating viral infections
What is the current status of gene therapy as a treatment option?
Under study to determine its safety and efficacy
What is the primary concern that has led to efforts to develop new treatments?
Cancer
What is the role of the RES in the immune response to non-viral DNA complexes?
Recognition of large particulates
What is a potential consequence of using high doses of cationic liposomes in gene therapy?
Acute inflammation and tissue damage
What is a potential health risk associated with gene therapy?
Cancer
What is the primary reason Naked DNA is ineffective in gene transfer?
Susceptibility to nuclease degradation in the systemic circulation
What is the primary mechanism of liposomal gene delivery?
Formation of organized structures with DNA through positive charge interaction
What is the function of the spacer in a cationic lipid?
To vary the length of the lipid structure
What is the primary advantage of microinjection in gene transfer?
Direct delivery of genetic material to the cytoplasm or nucleus
What is the primary factor affecting the interaction of liposomes with DNA?
pH, charge, and lipid structure
What is the primary limitation of early physical methods for gene transfer?
Rudimentary and severe techniques
What is the primary difference between the primary response and the response after repeated infection?
The primary response is slower and weaker
What is the main purpose of traditional active immunization?
To prevent infectious diseases
What is the crucial factor in designing a new vaccine?
The understanding of the mechanisms of protective immunity
What is required to prevent tetanus?
A high blood titer of antibody against tetanus toxin
What is the role of adjuvants in vaccine design?
To enhance the immune response
What is the main difference between active and passive immunization?
Active immunization is used for prevention, while passive immunization is used for therapy
Explore the promising area of gene therapy, a medical innovation that uses genes to treat or prevent diseases. Learn about the techniques and approaches being researched to replace mutated genes with healthy ones. Dive into the future of medicine!
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