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Questions and Answers
What is the primary cause of chronic inflammation of the liver associated with hepatitis B?
What is the primary cause of chronic inflammation of the liver associated with hepatitis B?
What was the first hepatitis B vaccine made from?
What was the first hepatitis B vaccine made from?
What is the main purpose of introducing the Multiple Drug Resistance (MDR) gene into bone marrow cells of cancer patients?
What is the main purpose of introducing the Multiple Drug Resistance (MDR) gene into bone marrow cells of cancer patients?
Which method was used to create the recombinant hepatitis B vaccine?
Which method was used to create the recombinant hepatitis B vaccine?
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What is the potential advantage of the cholera vaccine produced from genetically engineered potatoes?
What is the potential advantage of the cholera vaccine produced from genetically engineered potatoes?
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How does anti-angiogenesis gene therapy work as a cancer treatment?
How does anti-angiogenesis gene therapy work as a cancer treatment?
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What is the objective of therapeutic angiogenesis or VEGF gene therapy?
What is the objective of therapeutic angiogenesis or VEGF gene therapy?
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What characterizes the TOMAVAC tomato-based vaccine against COVID-19?
What characterizes the TOMAVAC tomato-based vaccine against COVID-19?
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What distinguishes in vivo gene therapy from ex vivo gene therapy?
What distinguishes in vivo gene therapy from ex vivo gene therapy?
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How are vitamins typically synthesized in living organisms?
How are vitamins typically synthesized in living organisms?
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What is a key characteristic of medical-therapeutic agents derived from vitamins?
What is a key characteristic of medical-therapeutic agents derived from vitamins?
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What does the vascular endothelial growth factor (VEGF) protein do in therapeutic angiogenesis?
What does the vascular endothelial growth factor (VEGF) protein do in therapeutic angiogenesis?
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What was one of the main challenges with the original method of hepatitis B vaccination?
What was one of the main challenges with the original method of hepatitis B vaccination?
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What is one key advantage of plant tissue culture techniques in biotechnology?
What is one key advantage of plant tissue culture techniques in biotechnology?
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Which of the following describes a disadvantage of genetically modified crops?
Which of the following describes a disadvantage of genetically modified crops?
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In the context of plant biotechnology, what is the significance of growth media composition?
In the context of plant biotechnology, what is the significance of growth media composition?
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What is one of the learning outcomes related to the enhancement of natural products?
What is one of the learning outcomes related to the enhancement of natural products?
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Which methodology is important for the quantitative determination of bioactive metabolites?
Which methodology is important for the quantitative determination of bioactive metabolites?
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Which of the following is an expected outcome from student presentations?
Which of the following is an expected outcome from student presentations?
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What aspect of plant biotechnology influences the growth regulators' effectiveness?
What aspect of plant biotechnology influences the growth regulators' effectiveness?
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How can computer technology benefit students studying plant biotechnology?
How can computer technology benefit students studying plant biotechnology?
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What is a key benefit of recombinant human insulin compared to animal-sourced insulin?
What is a key benefit of recombinant human insulin compared to animal-sourced insulin?
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Which of the following is NOT a general application of medical/pharmaceutical biotechnology?
Which of the following is NOT a general application of medical/pharmaceutical biotechnology?
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What process allows the introduction of the human insulin gene into bacteria for production?
What process allows the introduction of the human insulin gene into bacteria for production?
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Which substance was the first manufactured recombinant pharmaceutical?
Which substance was the first manufactured recombinant pharmaceutical?
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How does medical/pharmaceutical biotechnology aim to improve conventional pharmaceuticals?
How does medical/pharmaceutical biotechnology aim to improve conventional pharmaceuticals?
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What role do E. coli bacteria play in the production of pharmaceuticals?
What role do E. coli bacteria play in the production of pharmaceuticals?
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Which of the following is a direct application of pharmaceutical biotechnology?
Which of the following is a direct application of pharmaceutical biotechnology?
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Which product is NOT typically produced by medical biotechnology?
Which product is NOT typically produced by medical biotechnology?
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What is the role of thrombolytic alteplase in medical biotechnology?
What is the role of thrombolytic alteplase in medical biotechnology?
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Which ingredient is NOT typically found in vaccines?
Which ingredient is NOT typically found in vaccines?
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How do recombinant vaccines differ from conventionally produced vaccines?
How do recombinant vaccines differ from conventionally produced vaccines?
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What is necessary for the production of recombinant vaccines?
What is necessary for the production of recombinant vaccines?
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What is one benefit of using alteplase over other thrombolytics such as streptokinase?
What is one benefit of using alteplase over other thrombolytics such as streptokinase?
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What type of microorganisms are typically used in the production of vaccines?
What type of microorganisms are typically used in the production of vaccines?
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What triggers the immune system to produce specific antibodies in a vaccinated individual?
What triggers the immune system to produce specific antibodies in a vaccinated individual?
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Which of the following steps is involved in the production of recombinant vaccines?
Which of the following steps is involved in the production of recombinant vaccines?
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What is the primary purpose of the coli bacterial strain mentioned?
What is the primary purpose of the coli bacterial strain mentioned?
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What is the first step in the Reichstein–Grüssner process for vitamin C production?
What is the first step in the Reichstein–Grüssner process for vitamin C production?
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How is vitamin D primarily synthesized in the human body?
How is vitamin D primarily synthesized in the human body?
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What conversion occurs in the liver during vitamin D metabolism?
What conversion occurs in the liver during vitamin D metabolism?
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What role does the Actinomyces hyovaginalis bacterium play in vitamin D metabolism?
What role does the Actinomyces hyovaginalis bacterium play in vitamin D metabolism?
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Which of the following best describes gene therapy?
Which of the following best describes gene therapy?
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What is produced at the final step of the Reichstein–Grüssner process?
What is produced at the final step of the Reichstein–Grüssner process?
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What is the second hydroxylation of vitamin D primarily responsible for?
What is the second hydroxylation of vitamin D primarily responsible for?
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Flashcards
What is plant tissue culture?
What is plant tissue culture?
Plant tissue culture is a technique that involves growing plant cells, tissues, or organs in a controlled environment outside of their natural habitat.
How can plant tissue culture be used for conservation?
How can plant tissue culture be used for conservation?
Plant tissue culture can be used to produce large numbers of identical plants, which is useful for propagating rare or endangered species.
How can plant tissue culture be used for disease control?
How can plant tissue culture be used for disease control?
Plant tissue culture can be used to produce disease-free plants, which is important for agriculture and horticulture.
What is the link between biotechnology and pharmaceutical development?
What is the link between biotechnology and pharmaceutical development?
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What are genetically modified (GM) crops?
What are genetically modified (GM) crops?
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How can genetically modified (GM) crops improve agriculture?
How can genetically modified (GM) crops improve agriculture?
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What are some of the concerns surrounding genetically modified (GM) crops?
What are some of the concerns surrounding genetically modified (GM) crops?
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What is quantitative analysis of bioactive metabolites?
What is quantitative analysis of bioactive metabolites?
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Medical/Pharmaceutical Biotechnology
Medical/Pharmaceutical Biotechnology
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General Applications of Pharmaceutical Biotechnology
General Applications of Pharmaceutical Biotechnology
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Recombinant Human Insulin
Recombinant Human Insulin
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General Applications of Biotechnology
General Applications of Biotechnology
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Human Recombinant Insulin Production
Human Recombinant Insulin Production
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Pharmaceutical Biotechnology and Enzyme Production
Pharmaceutical Biotechnology and Enzyme Production
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Pharmaceutical Biotechnology and Vaccine Production
Pharmaceutical Biotechnology and Vaccine Production
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Pharmaceutical Biotechnology and Vitamins Production
Pharmaceutical Biotechnology and Vitamins Production
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Recombinant protein production
Recombinant protein production
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Amylase
Amylase
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Thrombolytic alteplase
Thrombolytic alteplase
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Vaccination
Vaccination
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Recombinant vaccine
Recombinant vaccine
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Antigen
Antigen
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Antibodies
Antibodies
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Recombinant vaccine production for hepatitis B
Recombinant vaccine production for hepatitis B
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Edible vaccines
Edible vaccines
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Potato-based cholera vaccine
Potato-based cholera vaccine
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Tomato-based COVID-19 vaccine (TOMAVAC)
Tomato-based COVID-19 vaccine (TOMAVAC)
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Viral entry mechanism through the spike protein
Viral entry mechanism through the spike protein
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Vitamins - essential micronutrients
Vitamins - essential micronutrients
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Medical applications of vitamins
Medical applications of vitamins
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Biotechnology in vitamin production
Biotechnology in vitamin production
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In vivo gene therapy
In vivo gene therapy
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Ex vivo gene therapy
Ex vivo gene therapy
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Anti-angiogenesis gene therapy
Anti-angiogenesis gene therapy
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Therapeutic angiogenesis
Therapeutic angiogenesis
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Multidrug resistance (MDR) gene therapy
Multidrug resistance (MDR) gene therapy
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What is the significance of the coli bacterial strain mentioned?
What is the significance of the coli bacterial strain mentioned?
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Explain the industrial process for producing Vitamin C.
Explain the industrial process for producing Vitamin C.
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Explain the synthesis of vitamin D.
Explain the synthesis of vitamin D.
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How can Actinomyces hyovaginalis be used in Vitamin D production?
How can Actinomyces hyovaginalis be used in Vitamin D production?
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What is Gene Therapy?
What is Gene Therapy?
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How can gene therapy be delivered?
How can gene therapy be delivered?
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Study Notes
Biotechnological Production of Herbal Drugs [PPC505]
- Syllabus covers advising, registration, biotechnology, plant tissue culture, plant genetic manipulation, pharmaceutical applications, student presentations and exams.
- Weeks 1-15 are outlined, detailing specific topics and dates for lectures, midterm exams, and final exams.
- Learning outcomes include describing biotechnology types and importance, recognizing plant tissue culture principles, illustrating production concepts for pharmaceuticals, demonstrating the relationship between growth media and yield, describing genetically modified crops, and explaining different analytical methods for bioactive metabolites.
- Further learning outcomes include assessment of experimental schemes, analysis of methods and elicitation protocols for natural product production, interpretation of transgenic plant protocols, development of team-working and presentation skills, and computer technology use.
- The agenda focuses on plant biotechnology and pharmaceutical applications of biotechnology.
- General applications of modern biotechnology in the pharmaceutical field, encompassing creation of new pharmaceuticals, safer versions of existing pharmaceuticals, and cost-effective production of similar substances.
- Recombinant human insulin is highlighted as a prime example, contrasting it with animal insulin's differences .
- Modern biotechnology involves hormone, gene, antibiotic, vaccine, interferon, vitamin production, as well as antenatal diagnosis for preventing genetic diseases.
- Specific applications include pharmaceutical biotechnology and hormone production, enzyme production, vaccine production, vitamin production, and gene therapy.
- Human recombinant insulin is the first human hormone produced through recombinant DNA technology, involving gene insertion into plasmids and transferring them into bacteria (E. coli or Saccharomyces cerevisiae).
- Insulin lispro is a genetically modified human insulin with peptide structure modifications affecting its action.
- Erythropoietin (EPO) regulates red blood cell production and is used for anemia treatment.
- Human growth hormone (hGH) is vital for growth, and recombinant hGH has replaced the use of cadaver-derived hormone.
- Amylase has various industrial and digestive applications, involving recombinant DNA technology.
- Thrombolytic enzyme (Alteplase) dissolves blood clots in the circulatory system.
- Vaccination is an effective disease control tool mimicking natural specific defense mechanism for pathogen resistance.
- Vaccines use killed microorganisms, non-virulent microorganisms, and microbial components.
- Recombinant vaccines are produced by inserting the gene into suitable carriers and expressing/purifying the material.
- Hepatitis B is a significant global health concern
- Genetically engineered potatoes for cholera vaccine production (TOMAVAC) illustrate edible vaccines like a tomato based edible vaccine for Covid-19.
- Vitamins are essential micronutrients for metabolism in living organisms, synthesized naturally and can also be produced through biotechnology.
- Vitamin production through chemical synthesis has environmental concerns whereas microbial methods are safer and more sustainable.
- Vitamins B12 and C are produced via fermentation from microorganisms like Pseudomonas denitrificans, Propionibacterium freudenreichii and Acetobacter suboxydans/Gluconobacter oxydans respectively, requiring various purifying steps.
- Vitamin D is synthesized in skin using UV light or ingested from dietary sources.
- Gene therapy involves inserting genetic material into cells for disease prevention, control, or cure; two main methods exist: in vivo and ex vivo.
- Multidrug resistance (MDR) gene therapy for cancer and anti-angiogenesis gene therapy to decrease tumor angiogenesis are highlighted.
- Future lectures will include student presentations about plant biotechnology.
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Description
Test your knowledge on gene therapy techniques and vaccine development, including topics such as hepatitis B vaccines and anti-angiogenesis strategies in cancer treatment. This quiz delves into the scientific principles behind various medical therapies and biotechnology innovations. Explore the advances in genetic engineering and their implications for health.