translation 1

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Where does translation occur in eukaryotes?

Nucleus

Mitochondria

Endoplasmic Reticulum

Cytoplasm (correct)

What is the main function of the small ribosomal subunit?

Facilitates the movement of tRNAs from A to P site

Peptide bond formation

Holds the decoding center (correct)

Contains the peptidyl transferase center

Which site on the ribosome is responsible for the last amino acid added to the polypeptide chain?

T-site

P-site (correct)

E-site

A-site

What is a common feature of all tRNAs in terms of their secondary structure?

Clover-leaf structure (B) Signup and view all the answers

What is the purpose of the initiation complex in translation?

Position the translation start site (D) Signup and view all the answers

Which process involves Aminoacyl-tRNA delivery, Peptide bond formation, and Translocation?

Elongation (B) Signup and view all the answers

What is the role of the ribosome complex in maintaining a 6 bp contact with the mRNA?

To prevent frameshifting (D) Signup and view all the answers

Which release factor recognizes the UAG codon during translation termination?

RF1 (C) Signup and view all the answers

What is the purpose of EF-G during the dissociation of the ribosome complex from the mRNA?

Removing uncharged tRNA from the P-site (B) Signup and view all the answers

In co-translational control, how does the tryptophan operon regulate gene expression?

By facilitating protein production (C) Signup and view all the answers

What is the main function of RF3 during translation termination?

Helping RF1 and RF2 in their roles (B) Signup and view all the answers

How does the release factor cause protein release during translation termination?

By transferring polypeptide to water instead of the next tRNA (D) Signup and view all the answers

What is the primary structure of a protein?

The sequence of amino acids in a polypeptide chain (D) Signup and view all the answers

Which process involves the enzymatic synthesis of RNA from a DNA template?

Transcription (C) Signup and view all the answers

What is the term used to describe local folded structures within a polypeptide?

Secondary structure (D) Signup and view all the answers

Which genetic material is translated into working parts in a cell?

Messenger RNA (mRNA) (D) Signup and view all the answers

What is responsible for the three-dimensional structure of a protein primarily due to interactions between the R groups of amino acids?

Tertiary structure (C) Signup and view all the answers

Which step forms the first stage in gene expression?

Transcription (D) Signup and view all the answers

What is the main role of the trp operon?

Encoding biosynthetic enzymes for tryptophan (C) Signup and view all the answers

How is the trp operon expression affected by tryptophan levels?

Expressed when tryptophan levels are low (A) Signup and view all the answers

What is the function of the trp repressor?

Block expression from the operon when bound to tryptophan (C) Signup and view all the answers

What happens if there is NO tryptophan present during translation of the attenuator polypeptide?

The ribosome stalls and an anti-terminator hairpin structure is generated. (A) Signup and view all the answers

Where is the attenuator sequence located in the trp operon?

Between the operator and the first gene of the operon (C) Signup and view all the answers

Which sequences are responsible for generating the anti-terminator and terminator hairpin structures during translation?

Anti-terminator: sequences 2 and 3; Terminator: sequences 3 and 4 (B) Signup and view all the answers

What does the attenuator sequence in the leader region encode?

Self-complementary sections for hairpin formation (D) Signup and view all the answers

How does attenuation function as a control mechanism in protein translation?

By inducing the ribosome to stall in response to specific amino acid levels. (A) Signup and view all the answers

How does attenuation work as a control mechanism in the trp operon?

Stops ribosome progression by forming hairpin structures (A) Signup and view all the answers

What effect does co-translational control have on protein synthesis in the presence of abundant tryptophan?

Translation is terminated prematurely. (D) Signup and view all the answers

What physicochemical properties are characteristic of proteins according to Dr. Mark Carlile's lecture?

Consist only of hydrophobic amino acids. (B) Signup and view all the answers

How can interference with the translation process impact gene expression control?

It could disrupt the formation of hairpin structures in mRNA. (C) Signup and view all the answers

What is the consequence of having NO tryptophan present during translation of the attenuator polypeptide?

Ribosome stalls and an anti-terminator hairpin structure is generated Signup and view all the answers

How is the mRNA sequence turned into protein during translation?

Through the process of protein synthesis Signup and view all the answers

What is the role of the ribosome complex in maintaining a 6 bp contact with the mRNA?

To ensure proper translation and reading of the genetic code Signup and view all the answers

What is the primary function of transfer RNAs (tRNAs) in protein synthesis?

Delivering amino acids to the ribosome Signup and view all the answers

How was the genetic code elucidated experimentally according to Dr. Mark Carlile's lecture?

Through decoding the mRNA sequences and understanding the codons Signup and view all the answers

translation 1

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Questions and Answers

Where does translation occur in eukaryotes?

What is the main function of the small ribosomal subunit?

Which site on the ribosome is responsible for the last amino acid added to the polypeptide chain?

What is a common feature of all tRNAs in terms of their secondary structure?

What is the purpose of the initiation complex in translation?

Which process involves Aminoacyl-tRNA delivery, Peptide bond formation, and Translocation?

What is the role of the ribosome complex in maintaining a 6 bp contact with the mRNA?

Which release factor recognizes the UAG codon during translation termination?

What is the purpose of EF-G during the dissociation of the ribosome complex from the mRNA?

In co-translational control, how does the tryptophan operon regulate gene expression?

What is the main function of RF3 during translation termination?

How does the release factor cause protein release during translation termination?

What is the primary structure of a protein?

Which process involves the enzymatic synthesis of RNA from a DNA template?

What is the term used to describe local folded structures within a polypeptide?

Which genetic material is translated into working parts in a cell?

What is responsible for the three-dimensional structure of a protein primarily due to interactions between the R groups of amino acids?

Which step forms the first stage in gene expression?

What is the main role of the trp operon?

How is the trp operon expression affected by tryptophan levels?

What is the function of the trp repressor?

What happens if there is NO tryptophan present during translation of the attenuator polypeptide?

Where is the attenuator sequence located in the trp operon?

Which sequences are responsible for generating the anti-terminator and terminator hairpin structures during translation?

What does the attenuator sequence in the leader region encode?

How does attenuation function as a control mechanism in protein translation?

How does attenuation work as a control mechanism in the trp operon?

What effect does co-translational control have on protein synthesis in the presence of abundant tryptophan?

What physicochemical properties are characteristic of proteins according to Dr. Mark Carlile's lecture?

How can interference with the translation process impact gene expression control?

What is the consequence of having NO tryptophan present during translation of the attenuator polypeptide?

How is the mRNA sequence turned into protein during translation?

What is the role of the ribosome complex in maintaining a 6 bp contact with the mRNA?

What is the primary function of transfer RNAs (tRNAs) in protein synthesis?

How was the genetic code elucidated experimentally according to Dr. Mark Carlile's lecture?

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