Gene Expression and Selection Marker Quiz
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Questions and Answers

Which method is used for selecting positive clones that have been successfully transfected?

  • Selective pressure
  • Cell line mutation
  • Antibiotic selection (correct)
  • Auxotrophy
  • What does gene amplification refer to?

  • Silencing of a gene within the genome of a cell
  • Expansion in copy number of a gene within the genome of a cell (correct)
  • Deletion of a gene within the genome of a cell
  • Reduction in copy number of a gene within the genome of a cell
  • Which protein is associated with selective pressure for increasing protein expression?

  • Dihydrofolate reductase (DHFR) (correct)
  • Glutamine synthetase (GS)
  • Streptomycin
  • Ampicillin
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