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GEN3001: Introduction to Reverse Genetic Approaches and Disease Modelling in Drosophila

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GEN3001: Introduction to Reverse Genetic Approaches and Disease Modelling in Drosophila

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Questions and Answers

What is a key feature of Drosophila that makes it a suitable genetic model organism?

Difficult to culture in a lab setting

Long life cycle of 30 days

Lack of genetic tools for research

Short life cycle of 12 days (correct)

What is the main idea of the passage?

Drosophila is not a useful model organism in biomedical research.

Essential genes in the Drosophila genome are not likely to be conserved.

The Drosophila genome contains a large number of protein-coding genes with many having unknown functions. (correct)

Mutations caused by X-rays in Drosophila have no relevance in biomedical research.

Which resource provides a wealth of biological knowledge for Drosophila research?

Flybase (correct)

Catbase

Dogbase

Mousebase

Who discovered homeotic genes in Drosophila in 1978?

Ed Lewis Signup and view all the answers

Why are balancer chromosomes used in Drosophila research?

To prevent recombination between homologous chromosomes Signup and view all the answers

What do more than 60% of Drosophila genes have according to the passage?

Human homologs with different functions Signup and view all the answers

What is the significance of Toll receptors in Drosophila according to the passage?

Involved in protection against various immune challenges, including viral, microbial, autoimmune, and allergies. Signup and view all the answers

What is a characteristic of Drosophila that contributes to its usefulness in disease modeling?

Conserved genes and cellular processes Signup and view all the answers

What factor distinguishes Drosophila from other model organisms in terms of ethical constraints?

Fewer ethical constraints compared to other model organisms Signup and view all the answers

What percentage of Drosophila genes are considered essential for survival?

~33% Signup and view all the answers