GEN3001: Introduction to Reverse Genetic Approaches and Disease Modelling in Drosophila
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Questions and Answers

What is a key feature of Drosophila that makes it a suitable genetic model organism?

  • Difficult to culture in a lab setting
  • Long life cycle of 30 days
  • Lack of genetic tools for research
  • Short life cycle of 12 days (correct)

What is the main idea of the passage?

  • Drosophila is not a useful model organism in biomedical research.
  • Essential genes in the Drosophila genome are not likely to be conserved.
  • The Drosophila genome contains a large number of protein-coding genes with many having unknown functions. (correct)
  • Mutations caused by X-rays in Drosophila have no relevance in biomedical research.

Which resource provides a wealth of biological knowledge for Drosophila research?

  • Flybase (correct)
  • Catbase
  • Dogbase
  • Mousebase

Who discovered homeotic genes in Drosophila in 1978?

<p>Ed Lewis (C)</p> Signup and view all the answers

Why are balancer chromosomes used in Drosophila research?

<p>To prevent recombination between homologous chromosomes (D)</p> Signup and view all the answers

What do more than 60% of Drosophila genes have according to the passage?

<p>Human homologs with different functions (A)</p> Signup and view all the answers

What is the significance of Toll receptors in Drosophila according to the passage?

<p>Involved in protection against various immune challenges, including viral, microbial, autoimmune, and allergies. (A)</p> Signup and view all the answers

What is a characteristic of Drosophila that contributes to its usefulness in disease modeling?

<p>Conserved genes and cellular processes (A)</p> Signup and view all the answers

What factor distinguishes Drosophila from other model organisms in terms of ethical constraints?

<p>Fewer ethical constraints compared to other model organisms (C)</p> Signup and view all the answers

What percentage of Drosophila genes are considered essential for survival?

<p>~33% (D)</p> Signup and view all the answers

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