Gastrointestinal, Urinary, and Liver Disorders Quiz
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Questions and Answers

What are the therapeutic effects of Saw Palmetto?

  • Anti-Inflammatory Effects (correct)
  • Anti-Androgenic Effects (correct)

    • What is the scientific name for Saw Palmetto?

    Serenoa repens

    Which of the following is not an indication for Saw Palmetto according to Commission E?

  • Irritable bladder
  • Prostate complaints
  • Dyspeptic complaints (correct)

    • Saw Palmetto is believed to have estrogen-like effects.

    <p>True</p> Signup and view all the answers

    What is the scientific name for Pumpkin?

    <p>Cucurbita pepo</p> Signup and view all the answers

    Which of the following is not a therapeutic effect of Pumpkin?

    <p>Antiviral</p> Signup and view all the answers

    Pumpkin is approved by Commission E for the treatment of irritable bladder and prostate complaints.

    <p>True</p> Signup and view all the answers

    What are the therapeutic effects of Turmeric? (Select all that apply)

    <p>anti-inflammatory</p> Signup and view all the answers

    The use of Turmeric is contraindicated in patients with obstructed biliary ducts.

    <p>True</p> Signup and view all the answers

    What is the scientific name for Devil's Claw?

    <p>Harpagophytum procumbens</p> Signup and view all the answers

    Devil's Claw stimulates gastric juice secretion?

    <p>True</p> Signup and view all the answers

    What is the scientific name for Dandelion?

    <p>Taraxacum officinale</p> Signup and view all the answers

    What are the therapeutic effects of Dandelion? (Select all that apply)

    <p>Secretolytic</p> Signup and view all the answers

    Dandelion is approved by Commission E for the treatment of infections of the urinary tract?

    <p>True</p> Signup and view all the answers

    What is the scientific name for Alpine Cranberry?

    <p>Vaccinium vitis-ideae</p> Signup and view all the answers

    Alpine Cranberry is an antiviral and a urine disinfectant.

    <p>True</p> Signup and view all the answers

    Alpine Cranberry is approved by Commission E for the treatment of urinary tract irritation, gout, rheumatism, and calculus?

    <p>False</p> Signup and view all the answers

    The urine-disinfecting effect of Alpine Cranberry is released in an alkaline environment?

    <p>True</p> Signup and view all the answers

    What is the scientific name for Celandine?

    <p>Chelidonium majus</p> Signup and view all the answers

    Celandine has what therapeutic effects? (Select all that apply)

    <p>Cholagogic</p> Signup and view all the answers

    Celandine is used for spasmodic pain of the bile ducts and the gastrointestinal tract.

    <p>True</p> Signup and view all the answers

    What is the scientific name for Milk Thistle?

    <p>Silybum marianum</p> Signup and view all the answers

    What are the liver-protective effects of Milk Thistle? (Select all that apply)

    <p>Increase glutathione production</p> Signup and view all the answers

    Milk Thistle has a regenerative effect on the liver.

    <p>True</p> Signup and view all the answers

    Milk Thistle is approved by Commission E for the treatment of toxic liver damage, chronic inflammatory liver disease, and hepatic cirrhosis?

    <p>True</p> Signup and view all the answers

    The concomitant use of silymarin and butyrophenones or phenothiazines can result in a reduction of lipid peroxidation?

    <p>True</p> Signup and view all the answers

    Silymarin has an antagonistic effect with yohimbine and phentolamine?

    <p>True</p> Signup and view all the answers

    What are the two therapeutic effects of Saw Palmetto (Serenoa repens)?

    <p>Anti-Inflammatory Effects</p> Signup and view all the answers

    The lipophilic extract of Saw Palmetto inhibits the binding of dihydrotestosterone (DHT) to the cytosolic androgenic receptor and alpha-1-adrenoceptor in the prostate.

    <p>True</p> Signup and view all the answers

    Saw Palmetto's anti-inflammatory effects are due to its ability to inhibit the synthesis of arachidonic acid inflammatory metabolites.

    <p>True</p> Signup and view all the answers

    Saw Palmetto extracts can antagonize the contracting effect of acetylcholine on urinary bladders.

    <p>True</p> Signup and view all the answers

    Saw Palmetto is approved by Commission E for which of the following conditions?

    <p>Prostate complaints</p> Signup and view all the answers

    Saw Palmetto is believed to exert estrogen, androgen, and alpha-adrenergic blocking effects.

    <p>True</p> Signup and view all the answers

    What is the effect of Saw Palmetto on anticoagulants?

    <p>Saw Palmetto is attributed to excessive bleeding in a surgical procedure, suggesting it might have anticoagulant effects.</p> Signup and view all the answers

    Pumpkin (Cucurbita pepo) contains cucurbitacin and delta7-sterols, which are similar in conformation to the Dihydrotestosterone.

    <p>True</p> Signup and view all the answers

    Cucurbitacin, found in Pumpkin, has anthelmintic properties.

    <p>True</p> Signup and view all the answers

    Pumpkin has demonstrated empirical efficacy in treating prostate hyperplasia.

    <p>True</p> Signup and view all the answers

    Pumpkin is known for its antiphlogistic and antioxidative effects.

    <p>True</p> Signup and view all the answers

    Which of the following conditions is Pumpkin (Cucurbita pepo) approved by Commission E for?

    <p>Irritable bladder</p> Signup and view all the answers

    Describe the case of the elderly man who was taking Curbicin.

    <p>The elderly man, not taking anticoagulants, experienced elevated INR levels while taking Curbicin, a herbal remedy containing Saw Palmetto and Pumpkin extracts, indicating potential anticoagulant effects.</p> Signup and view all the answers

    Turmeric (Curcuma domestica) exhibits antihepatotoxic, antihyperlipidemic, and anti-inflammatory effects.

    <p>True</p> Signup and view all the answers

    Turmeric's antioxidative properties stem from its ability to inhibit lipid peroxide formation in the liver.

    <p>True</p> Signup and view all the answers

    Turmeric inhibits prostaglandin formation in vivo.

    <p>False</p> Signup and view all the answers

    For which of the following conditions has Turmeric been approved by Commission E?

    <p>Loss of appetite</p> Signup and view all the answers

    What is the contraindication for using Turmeric?

    <p>Turmeric should not be used by patients with obstructed biliary ducts or gallstones.</p> Signup and view all the answers

    How does Devil's Claw (Harpagophytum procumbens) affect the digestive system?

    <p>Devil's Claw stimulates gastric juice secretion and is considered choleretic, meaning it increases bile secretion.</p> Signup and view all the answers

    What conditions is Devil's Claw approved by Commission E for?

    <p>Loss of appetite</p> Signup and view all the answers

    What is the contraindication for using Devil's Claw?

    <p>Devil's Claw should not be used in the presence of stomach or duodenal ulcers due to its stimulation of gastric juice secretion.</p> Signup and view all the answers

    Dandelion (Taraxacum officinale) has cholagogic and secretolytic effects in the upper intestinal tract.

    <p>True</p> Signup and view all the answers

    What conditions is Dandelion approved by Commission E for?

    <p>Liver and gall bladder complaints</p> Signup and view all the answers

    Alpine Cranberry (Vaccinium vitis-ideae) is antiviral and a urine disinfectant due to the tannin fraction.

    <p>True</p> Signup and view all the answers

    Alpine Cranberry is used to treat urinary tract irritation, gout, rheumatism, and calculus.

    <p>True</p> Signup and view all the answers

    The urine-disinfecting effect of hydroquinones in Alpine Cranberry occurs in both acidic and alkaline environments.

    <p>False</p> Signup and view all the answers

    It is recommended to avoid consuming purine-rich foods while taking Alpine Cranberry.

    <p>True</p> Signup and view all the answers

    Celandine (Chelidonium majus) has mild analgesic, cholagogic, antimicrobial, and central-sedative effects.

    <p>True</p> Signup and view all the answers

    Celandine acts as a spasmolytic on smooth muscles and has a nonspecific immune-stimulating effect.

    <p>True</p> Signup and view all the answers

    What condition is Celandine approved by Commission E for?

    <p>Liver and gallbladder complaints</p> Signup and view all the answers

    Milk Thistle (Silybum marianum) has hepatoprotective and liver regenerative effects, both attributed to silymarin and silibinin.

    <p>True</p> Signup and view all the answers

    Silymarin inhibits the entrance of toxins and blocks toxin-binding sites by altering the liver cell's outer membrane.

    <p>True</p> Signup and view all the answers

    Silibinin decreases the production of superoxide radicals and inhibits leukotriene formation by Kupffer cells.

    <p>True</p> Signup and view all the answers

    Silymarin increases glutathione production in the liver, intestines, and stomach, contributing to detoxification in liver cells.

    <p>True</p> Signup and view all the answers

    Silymarin stimulates RNA polymerase I in the cell nucleus, increasing ribosomal protein synthesis and the regenerative ability of the liver.

    <p>True</p> Signup and view all the answers

    Milk Thistle is used for toxic liver damage and as an adjunctive treatment in chronic inflammatory liver disease and hepatic cirrhosis.

    <p>True</p> Signup and view all the answers

    Milk Thistle's concomitant use with butyrophenones or phenothiazines can result in a reduction of lipid peroxidation.

    <p>True</p> Signup and view all the answers

    Silymarin has an antagonistic effect with yohimbine and phentolamine when given simultaneously.

    <p>True</p> Signup and view all the answers

    Study Notes

    Gastrointestinal Tract, Urinary Tract, and Liver Disorders

    • General Topic: This document covers various disorders related to the gastrointestinal tract, urinary tract, and liver.
    • Focus: The document specifically discusses the therapeutic effects and indications of certain plants, including their use in various conditions.

    Saw Palmetto (Serenoa repens)

    • Therapeutic Effects (Anti-Androgenic): The lipophilic extract of Saw Palmetto inhibits the binding of dihydrotestosterone (DHT) to androgen receptors in the prostate, preventing prostate hyperplasia. It also inhibits 5-alpha-reductase, similar to finasteride.
    • Therapeutic Effects (Anti-Inflammatory): Hexane extracts demonstrate anti-inflammatory activity by inhibiting the synthesis of arachidonic acid inflammatory metabolites (blocking cyclooxygenase and 5-lipoxygenase pathways). The drug also has anti-spasmodic properties, inhibiting calcium influx and sodium/calcium ion exchange.
    • Indications: Approved by Commission E for prostate complaints and irritable bladder.
    • Drug Interactions: Saw Palmetto is believed to affect estrogen, androgen, and alpha-adrenergic systems. The concomitant use of hormones, hormone-like drugs, or adrenergic drugs may need adjustment (for endocrine-related cancers).

    Pumpkin (Cucurbita pepo)

    • Therapeutic Effects: Contains cucurbitacins and delta-7 sterols similar in conformation to dihydrotestosterone. The drug exhibits anthelmintic properties.
    • Empirical Evidence: Shows evidence of efficacy for prostate hyperplasia. Also, has anti-inflammatory and antioxidant properties.
    • Indications: Approved by Commission E for irritated or inflamed bladder and prostate complaints.

    Turmeric (Curcuma domestica)

    • Therapeutic Effects: Possesses antihepatotoxic, antihyperlipidemic, and anti-inflammatory effects. Also has antioxidative properties (inhibits lipid peroxide formation in the liver), is antitumoral, and antimicrobial. Inhibits prostaglandin formation in vitro.
    • Indications: Approved by Commission E for dyspeptic complaints and loss of appetite.
    • Contraindications: Should not be used by patients with obstructed biliary ducts or gallstones without a doctor's supervision.

    Devil's Claw (Harpagophytum procumbens)

    • Therapeutic Effects: Stimulates gastric juice secretion, and is choleretic (increasing bile secretion).
    • Indications: Approved by Commission E for dyspeptic complaints, loss of appetite, and rheumatism.
    • Contraindications: Should not be used in the presence of stomach or duodenal ulcers, due to the stimulation of gastric juice secretion.

    Dandelion (Taraxacum officinale)

    • Therapeutic Effects: Exhibits cholagogic and secretolytic effects in the upper intestinal tract.
    • Indications: Approved by Commission E for dyspeptic complaints, urinary tract infections, and liver/gall bladder complaints. Loss of appetite is also an indication.

    Alpine Cranberry (Vaccinium vitis-ideae)

    • Therapeutic Effects: Antiviral and a urine disinfectant due to tannin fraction.
    • Indications: Unproven uses include: urinary tract irritation, gout, rheumatism, and calculus (stone complaints).
    • Precautions: Urine-disinfecting effect is only released in an alkaline environment in the urinary tract. Avoid simultaneous use with purine-containing foods (meat, kidney, heart, shellfish, etc.).

    Celandine (Chelidonium majus)

    • Therapeutic Effects: Exhibits mild analgesic, cholagogic, antimicrobial, and central-sedative effects. Also has spasmolytic (relaxing muscle spasms) effects on smooth muscles. Nonspecific immune-stimulating effect,
    • Indications: Approved by Commission E for liver and gallbladder complaints. Unproven: for spasmodic pain of the bile ducts and gastrointestinal tract.

    Milk Thistle (Silybum marianum)

    • Hepatoprotective Effects: Silymarin (silychristin and silydianin) inhibits toxin entry and binding, reduces superoxide radicals, and inhibits leukotriene formation. Increases glutathione production for detoxification. 
    • Liver Regenerative Effects: Stimulates RNA polymerase I in hepatocytes, increasing ribosomal protein synthesis and liver regeneration. Also a cholagogue (promotes bile flow).
    • Indications: Approved by Commission E for dyspeptic complaints, liver and gall bladder complaints. Also used for toxic liver damage, chronic inflammatory liver disease, and hepatic cirrhosis.
    • Drug Interactions: Concomitant use with butyrophenones or phenothiazines can reduce lipid peroxidation. Silymarin is antagonistic with yohimbine and phentolamine.

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    Gastrointestinal Tract, Urinary Tract and Liver Disorders PDF

    Description

    This quiz explores various disorders related to the gastrointestinal, urinary tracts, and liver, with a special focus on the therapeutic applications of specific plants. Discover the anti-androgenic and anti-inflammatory effects of Saw Palmetto, its mechanisms of action, and indicated conditions. Test your knowledge on how plants contribute to managing these disorders.

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