Gastrointestinal, Urinary, and Liver Disorders Quiz
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Questions and Answers

What are the therapeutic effects of Saw Palmetto?

  • Anti-Inflammatory Effects (correct)
  • Anti-Androgenic Effects (correct)

What is the scientific name for Saw Palmetto?

Serenoa repens

Which of the following is not an indication for Saw Palmetto according to Commission E?

  • Irritable bladder
  • Prostate complaints
  • Dyspeptic complaints (correct)

Saw Palmetto is believed to have estrogen-like effects.

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Pumpkin?

<p>Cucurbita pepo</p> Signup and view all the answers

Which of the following is not a therapeutic effect of Pumpkin?

<p>Antiviral (B)</p> Signup and view all the answers

Pumpkin is approved by Commission E for the treatment of irritable bladder and prostate complaints.

<p>True (A)</p> Signup and view all the answers

What are the therapeutic effects of Turmeric? (Select all that apply)

<p>anti-inflammatory (A), antihyperlipidemic (B), antihepatotoxic (C)</p> Signup and view all the answers

The use of Turmeric is contraindicated in patients with obstructed biliary ducts.

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Devil's Claw?

<p>Harpagophytum procumbens</p> Signup and view all the answers

Devil's Claw stimulates gastric juice secretion?

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Dandelion?

<p>Taraxacum officinale (B)</p> Signup and view all the answers

What are the therapeutic effects of Dandelion? (Select all that apply)

<p>Secretolytic (A), Cholagogic (B)</p> Signup and view all the answers

Dandelion is approved by Commission E for the treatment of infections of the urinary tract?

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Alpine Cranberry?

<p>Vaccinium vitis-ideae</p> Signup and view all the answers

Alpine Cranberry is an antiviral and a urine disinfectant.

<p>True (A)</p> Signup and view all the answers

Alpine Cranberry is approved by Commission E for the treatment of urinary tract irritation, gout, rheumatism, and calculus?

<p>False (B)</p> Signup and view all the answers

The urine-disinfecting effect of Alpine Cranberry is released in an alkaline environment?

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Celandine?

<p>Chelidonium majus</p> Signup and view all the answers

Celandine has what therapeutic effects? (Select all that apply)

<p>Cholagogic (A), Analgesic (C)</p> Signup and view all the answers

Celandine is used for spasmodic pain of the bile ducts and the gastrointestinal tract.

<p>True (A)</p> Signup and view all the answers

What is the scientific name for Milk Thistle?

<p>Silybum marianum</p> Signup and view all the answers

What are the liver-protective effects of Milk Thistle? (Select all that apply)

<p>Increase glutathione production (A), Inhibit the entrance of toxins (B), Decrease production of superoxide radicals (C), Block toxin-binding sites (D)</p> Signup and view all the answers

Milk Thistle has a regenerative effect on the liver.

<p>True (A)</p> Signup and view all the answers

Milk Thistle is approved by Commission E for the treatment of toxic liver damage, chronic inflammatory liver disease, and hepatic cirrhosis?

<p>True (A)</p> Signup and view all the answers

The concomitant use of silymarin and butyrophenones or phenothiazines can result in a reduction of lipid peroxidation?

<p>True (A)</p> Signup and view all the answers

Silymarin has an antagonistic effect with yohimbine and phentolamine?

<p>True (A)</p> Signup and view all the answers

What are the two therapeutic effects of Saw Palmetto (Serenoa repens)?

<p>Anti-Inflammatory Effects (B), Anti-Androgenic Effects (C)</p> Signup and view all the answers

The lipophilic extract of Saw Palmetto inhibits the binding of dihydrotestosterone (DHT) to the cytosolic androgenic receptor and alpha-1-adrenoceptor in the prostate.

<p>True (A)</p> Signup and view all the answers

Saw Palmetto's anti-inflammatory effects are due to its ability to inhibit the synthesis of arachidonic acid inflammatory metabolites.

<p>True (A)</p> Signup and view all the answers

Saw Palmetto extracts can antagonize the contracting effect of acetylcholine on urinary bladders.

<p>True (A)</p> Signup and view all the answers

Saw Palmetto is approved by Commission E for which of the following conditions?

<p>Prostate complaints (C), Irritable bladder (D)</p> Signup and view all the answers

Saw Palmetto is believed to exert estrogen, androgen, and alpha-adrenergic blocking effects.

<p>True (A)</p> Signup and view all the answers

What is the effect of Saw Palmetto on anticoagulants?

<p>Saw Palmetto is attributed to excessive bleeding in a surgical procedure, suggesting it might have anticoagulant effects.</p> Signup and view all the answers

Pumpkin (Cucurbita pepo) contains cucurbitacin and delta7-sterols, which are similar in conformation to the Dihydrotestosterone.

<p>True (A)</p> Signup and view all the answers

Cucurbitacin, found in Pumpkin, has anthelmintic properties.

<p>True (A)</p> Signup and view all the answers

Pumpkin has demonstrated empirical efficacy in treating prostate hyperplasia.

<p>True (A)</p> Signup and view all the answers

Pumpkin is known for its antiphlogistic and antioxidative effects.

<p>True (A)</p> Signup and view all the answers

Which of the following conditions is Pumpkin (Cucurbita pepo) approved by Commission E for?

<p>Irritable bladder (C), Prostate complaints (D)</p> Signup and view all the answers

Describe the case of the elderly man who was taking Curbicin.

<p>The elderly man, not taking anticoagulants, experienced elevated INR levels while taking Curbicin, a herbal remedy containing Saw Palmetto and Pumpkin extracts, indicating potential anticoagulant effects.</p> Signup and view all the answers

Turmeric (Curcuma domestica) exhibits antihepatotoxic, antihyperlipidemic, and anti-inflammatory effects.

<p>True (A)</p> Signup and view all the answers

Turmeric's antioxidative properties stem from its ability to inhibit lipid peroxide formation in the liver.

<p>True (A)</p> Signup and view all the answers

Turmeric inhibits prostaglandin formation in vivo.

<p>False (B)</p> Signup and view all the answers

For which of the following conditions has Turmeric been approved by Commission E?

<p>Loss of appetite (A), Dyspeptic complaints (D)</p> Signup and view all the answers

What is the contraindication for using Turmeric?

<p>Turmeric should not be used by patients with obstructed biliary ducts or gallstones.</p> Signup and view all the answers

How does Devil's Claw (Harpagophytum procumbens) affect the digestive system?

<p>Devil's Claw stimulates gastric juice secretion and is considered choleretic, meaning it increases bile secretion.</p> Signup and view all the answers

What conditions is Devil's Claw approved by Commission E for?

<p>Loss of appetite (B), Dyspeptic complaints (C)</p> Signup and view all the answers

What is the contraindication for using Devil's Claw?

<p>Devil's Claw should not be used in the presence of stomach or duodenal ulcers due to its stimulation of gastric juice secretion.</p> Signup and view all the answers

Dandelion (Taraxacum officinale) has cholagogic and secretolytic effects in the upper intestinal tract.

<p>True (A)</p> Signup and view all the answers

What conditions is Dandelion approved by Commission E for?

<p>Liver and gall bladder complaints (A), Dyspeptic complaints (B), Loss of appetite (C), Infections of the urinary tract (D)</p> Signup and view all the answers

Alpine Cranberry (Vaccinium vitis-ideae) is antiviral and a urine disinfectant due to the tannin fraction.

<p>True (A)</p> Signup and view all the answers

Alpine Cranberry is used to treat urinary tract irritation, gout, rheumatism, and calculus.

<p>True (A)</p> Signup and view all the answers

The urine-disinfecting effect of hydroquinones in Alpine Cranberry occurs in both acidic and alkaline environments.

<p>False (B)</p> Signup and view all the answers

It is recommended to avoid consuming purine-rich foods while taking Alpine Cranberry.

<p>True (A)</p> Signup and view all the answers

Celandine (Chelidonium majus) has mild analgesic, cholagogic, antimicrobial, and central-sedative effects.

<p>True (A)</p> Signup and view all the answers

Celandine acts as a spasmolytic on smooth muscles and has a nonspecific immune-stimulating effect.

<p>True (A)</p> Signup and view all the answers

What condition is Celandine approved by Commission E for?

<p>Liver and gallbladder complaints (C)</p> Signup and view all the answers

Milk Thistle (Silybum marianum) has hepatoprotective and liver regenerative effects, both attributed to silymarin and silibinin.

<p>True (A)</p> Signup and view all the answers

Silymarin inhibits the entrance of toxins and blocks toxin-binding sites by altering the liver cell's outer membrane.

<p>True (A)</p> Signup and view all the answers

Silibinin decreases the production of superoxide radicals and inhibits leukotriene formation by Kupffer cells.

<p>True (A)</p> Signup and view all the answers

Silymarin increases glutathione production in the liver, intestines, and stomach, contributing to detoxification in liver cells.

<p>True (A)</p> Signup and view all the answers

Silymarin stimulates RNA polymerase I in the cell nucleus, increasing ribosomal protein synthesis and the regenerative ability of the liver.

<p>True (A)</p> Signup and view all the answers

Milk Thistle is used for toxic liver damage and as an adjunctive treatment in chronic inflammatory liver disease and hepatic cirrhosis.

<p>True (A)</p> Signup and view all the answers

Milk Thistle's concomitant use with butyrophenones or phenothiazines can result in a reduction of lipid peroxidation.

<p>True (A)</p> Signup and view all the answers

Silymarin has an antagonistic effect with yohimbine and phentolamine when given simultaneously.

<p>True (A)</p> Signup and view all the answers

Flashcards

Saw Palmetto's anti-androgenic effects

Saw palmetto inhibits dihydrotestosterone (DHT) binding to receptors, preventing prostate enlargement. It also inhibits 5-alpha-reductase, similar to finasteride.

Saw Palmetto's anti-inflammatory effects

Saw palmetto extracts reduce inflammation by blocking the production of inflammatory molecules (arachidonic acid metabolites). It also has anti-spasmodic properties.

Saw Palmetto approved by Commission E indications

Saw Palmetto is approved to treat prostate complaints and an irritable bladder.

Saw Palmetto drug interactions

Saw palmetto may interact with hormones, hormone-like drugs, or adrenergic medications, potentially needing an adjustment in dosage.

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Saw Palmetto anticoagulant effect

Saw Palmetto has been linked to increased bleeding time in a patient undergoing surgery.

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Pumpkin's therapeutic effects

Pumpkin contains compounds like cucurbitacin (anthelmintic) and delta7-sterols, which are similar to dihydrotestosterone and show potential for treating prostate hyperplasia.

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Pumpkin approved by Commission E indications

Pumpkin is approved for irritable bladder complaints and prostate problems.

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Pumpkin anticoagulant effect

Pumpkin as part of a herbal remedy increased blood clotting times (INR) in a patient.

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Turmeric's therapeutic effects

Turmeric has anti-inflammatory, antioxidative, antitumoral, and antimicrobial effects.

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Turmeric approved by Commission E indications

Turmeric is approved to treat indigestion/dyspepsia and appetite loss.

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Turmeric contraindication

Avoid Turmeric in patients with blocked bile ducts or gallstones without medical supervision.

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Devil's Claw's therapeutic effect

Devil's Claw increases stomach acid and bile secretion.

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Devil's Claw approved by Commission E indications

Devil's Claw is approved for indigestion, appetite loss, and rheumatism.

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Devil's Claw contraindication

Avoid Devil's Claw in people with stomach or duodenum ulcers, as it increases stomach acid.

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Dandelion's therapeutic effect

Dandelion stimulates bile secretion.

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Dandelion approved by Commission E indications

Dandelion is approved for various conditions: indigestion, urinary tract infections, liver/gallbladder issues, and loss of appetite.

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Alpine Cranberry's therapeutic effect

Alpine Cranberry has antiviral and urine-disinfecting properties (tannin).

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Alpine Cranberry precautions

The urine-disinfecting effect is best in alkaline urine. Avoid foods that increase uric acid.

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Celandine's therapeutic effects

Celandine has mild pain relief, stimulates bile flow, is antimicrobial, and has a calming effect on the nervous system.

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Celandine approved by Commission E indications

Celandine is approved by Commission E for liver and gallbladder complaints.

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Milk Thistle's hepatoprotective effects

Milk thistle protects the liver by blocking toxin entry and decreasing the production of harmful molecules.

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Milk Thistle's regenerative effects

Milk thistle stimulates the liver's ability to repair itself.

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Milk Thistle approved by Commission E indications

Milk thistle is approved for conditions like indigestion, liver & gallbladder problems. and toxic liver damage.

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Milk Thistle drug interactions

Milk thistle may interact with certain types of antipsychotic and other medications.

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Saw Palmetto's Action

Saw Palmetto acts by blocking the binding of dihydrotestosterone (DHT) to receptors in the prostate, preventing prostate enlargement. It also inhibits 5-alpha-reductase, an enzyme that converts testosterone into DHT.

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Saw Palmetto's Effects

Saw Palmetto has two main effects: 1) Anti-androgenic: reduces the effects of male hormones, preventing prostate growth. 2) Anti-inflammatory: reduces inflammation in the prostate.

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Saw Palmetto for Prostate

Saw Palmetto is approved by Commission E for treating prostate complaints, specifically benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges.

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Saw Palmetto & Bleeding

Saw Palmetto has been associated with excessive bleeding during surgery in a case report. It's important to inform your doctor about any herbal supplements you're taking before surgery.

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Pumpkin's Benefit

Pumpkin contains compounds that may help reduce prostate enlargement. It also has anti-inflammatory and antioxidant properties.

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Pumpkin's Approved Uses

Pumpkin is approved by Commission E for treating urinary bladder irritations and prostate complaints.

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Turmeric & Liver Health

Turmeric is known for its benefits for the liver. It has anti-inflammatory, antioxidant, and protective effects on the liver.

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Turmeric's Approved Uses

Turmeric is approved by Commission E for treating indigestion and loss of appetite.

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Turmeric & Blocked Bile Ducts

If you have blocked bile ducts or gallstones, it's important to avoid Turmeric or take it only under a doctor's supervision.

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Devil's Claw's Effect

Devil's Claw stimulates the production of gastric juice and increases bile secretion.

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Devil's Claw's Approved Uses

Devil's Claw is approved by Commission E for treating indigestion, loss of appetite, and rheumatic conditions.

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Devil's Claw & Stomach Ulcers

People with stomach or duodenal ulcers should avoid Devil's Claw because it stimulates gastric juice production, which could worsen their condition.

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Dandelion's Benefit

Dandelion helps stimulate the production of bile and promotes its flow in the digestive system.

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Dandelion's Approved Uses

Dandelion is approved by Commission E for treating various conditions related to digestion, urinary tract, liver, and gallbladder. It's also used for loss of appetite.

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Alpine Cranberry's Effect

Alpine Cranberry has antiviral and urine disinfecting properties. It contains tannins that help kill bacteria and viruses in the urinary tract.

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Alpine Cranberry's Approved Uses

Alpine Cranberry is often used to treat urinary tract irritations, gout, rheumatism, and kidney stones, although its effectiveness for all these conditions isn't definitively proven.

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Alpine Cranberry & Alkaline Environment

The urine-disinfecting effect of Alpine Cranberry works best in alkaline urine. Acidic urine may decrease its effectiveness.

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Celandine's Effects

Celandine has various properties, including pain relief, stimulation of bile flow, antimicrobial effects, and calming effects on the nervous system.

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Celandine's Approved Uses

Celandine is approved by Commission E for treating liver and gallbladder problems.

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Milk Thistle & Liver Protection

Milk thistle contains a compound called silymarin, which protects the liver from damage caused by toxins.

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Milk Thistle's Regenerative Property

Milk thistle can help the liver regenerate and repair itself after damage.

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Milk Thistle's Approved Uses

Milk thistle is approved by Commission E for treating indigestion, liver and gallbladder problems, and toxic liver damage.

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Milk Thistle & Interactions

Milk Thistle can interact with certain medications, including antipsychotics and drugs that affect the nervous system.

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Study Notes

Gastrointestinal Tract, Urinary Tract, and Liver Disorders

  • General Topic: This document covers various disorders related to the gastrointestinal tract, urinary tract, and liver.
  • Focus: The document specifically discusses the therapeutic effects and indications of certain plants, including their use in various conditions.

Saw Palmetto (Serenoa repens)

  • Therapeutic Effects (Anti-Androgenic): The lipophilic extract of Saw Palmetto inhibits the binding of dihydrotestosterone (DHT) to androgen receptors in the prostate, preventing prostate hyperplasia. It also inhibits 5-alpha-reductase, similar to finasteride.
  • Therapeutic Effects (Anti-Inflammatory): Hexane extracts demonstrate anti-inflammatory activity by inhibiting the synthesis of arachidonic acid inflammatory metabolites (blocking cyclooxygenase and 5-lipoxygenase pathways). The drug also has anti-spasmodic properties, inhibiting calcium influx and sodium/calcium ion exchange.
  • Indications: Approved by Commission E for prostate complaints and irritable bladder.
  • Drug Interactions: Saw Palmetto is believed to affect estrogen, androgen, and alpha-adrenergic systems. The concomitant use of hormones, hormone-like drugs, or adrenergic drugs may need adjustment (for endocrine-related cancers).

Pumpkin (Cucurbita pepo)

  • Therapeutic Effects: Contains cucurbitacins and delta-7 sterols similar in conformation to dihydrotestosterone. The drug exhibits anthelmintic properties.
  • Empirical Evidence: Shows evidence of efficacy for prostate hyperplasia. Also, has anti-inflammatory and antioxidant properties.
  • Indications: Approved by Commission E for irritated or inflamed bladder and prostate complaints.

Turmeric (Curcuma domestica)

  • Therapeutic Effects: Possesses antihepatotoxic, antihyperlipidemic, and anti-inflammatory effects. Also has antioxidative properties (inhibits lipid peroxide formation in the liver), is antitumoral, and antimicrobial. Inhibits prostaglandin formation in vitro.
  • Indications: Approved by Commission E for dyspeptic complaints and loss of appetite.
  • Contraindications: Should not be used by patients with obstructed biliary ducts or gallstones without a doctor's supervision.

Devil's Claw (Harpagophytum procumbens)

  • Therapeutic Effects: Stimulates gastric juice secretion, and is choleretic (increasing bile secretion).
  • Indications: Approved by Commission E for dyspeptic complaints, loss of appetite, and rheumatism.
  • Contraindications: Should not be used in the presence of stomach or duodenal ulcers, due to the stimulation of gastric juice secretion.

Dandelion (Taraxacum officinale)

  • Therapeutic Effects: Exhibits cholagogic and secretolytic effects in the upper intestinal tract.
  • Indications: Approved by Commission E for dyspeptic complaints, urinary tract infections, and liver/gall bladder complaints. Loss of appetite is also an indication.

Alpine Cranberry (Vaccinium vitis-ideae)

  • Therapeutic Effects: Antiviral and a urine disinfectant due to tannin fraction.
  • Indications: Unproven uses include: urinary tract irritation, gout, rheumatism, and calculus (stone complaints).
  • Precautions: Urine-disinfecting effect is only released in an alkaline environment in the urinary tract. Avoid simultaneous use with purine-containing foods (meat, kidney, heart, shellfish, etc.).

Celandine (Chelidonium majus)

  • Therapeutic Effects: Exhibits mild analgesic, cholagogic, antimicrobial, and central-sedative effects. Also has spasmolytic (relaxing muscle spasms) effects on smooth muscles. Nonspecific immune-stimulating effect,
  • Indications: Approved by Commission E for liver and gallbladder complaints. Unproven: for spasmodic pain of the bile ducts and gastrointestinal tract.

Milk Thistle (Silybum marianum)

  • Hepatoprotective Effects: Silymarin (silychristin and silydianin) inhibits toxin entry and binding, reduces superoxide radicals, and inhibits leukotriene formation. Increases glutathione production for detoxification. 
  • Liver Regenerative Effects: Stimulates RNA polymerase I in hepatocytes, increasing ribosomal protein synthesis and liver regeneration. Also a cholagogue (promotes bile flow).
  • Indications: Approved by Commission E for dyspeptic complaints, liver and gall bladder complaints. Also used for toxic liver damage, chronic inflammatory liver disease, and hepatic cirrhosis.
  • Drug Interactions: Concomitant use with butyrophenones or phenothiazines can reduce lipid peroxidation. Silymarin is antagonistic with yohimbine and phentolamine.

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Description

This quiz explores various disorders related to the gastrointestinal, urinary tracts, and liver, with a special focus on the therapeutic applications of specific plants. Discover the anti-androgenic and anti-inflammatory effects of Saw Palmetto, its mechanisms of action, and indicated conditions. Test your knowledge on how plants contribute to managing these disorders.

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