Gastrointestinal Risks of NSAIDs Quiz
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Questions and Answers

What type of nonpharmacologic treatments does the American 2019 guidelines recommend for osteoarthritis?

  • Acupuncture
  • Tai chi (correct)
  • Weight lifting
  • Running marathons

    • Which outcome measure is used to assess treatment efficacy in osteoarthritis according to the text?

  • Blood pressure
  • WOMAC: pain & walking distance (correct)
  • Cholesterol levels
  • BMI

    • What is the current status of acetaminophen use in osteoarthritis treatment based on the Lancet meta-analysis?

  • It has shown significant benefits in reducing pain and improving movement
  • It is being phased out due to adverse effects
  • It is recommended as a first-line treatment
  • It has no impact on pain management (correct)

    • What is the primary reason for acetaminophen still being widely used despite its ineffectiveness in osteoarthritis treatment?

    <p>Avoidance of COX-1 inhibition and related complications</p> Signup and view all the answers

    What is a potential consequence of long-term use of non-selective NSAIDs in osteoarthritis?

    <p>Increased risk of peptic ulcer disease</p> Signup and view all the answers

    Which pharmacologic treatment is considered a strong recommendation according to the American 2019 guidelines for osteoarthritis?

    <p>Topical NSAIDs</p> Signup and view all the answers

    Which medication is classified as a weak opiate and conditionally recommended in the American 2019 guidelines for osteoarthritis?

    <p>Tramadol</p> Signup and view all the answers

    What is the maximum daily dose of indomethacin recommended for gout, ankylosing spondylitis, and psoriatic arthritis?

    <p>Up to 150 mg</p> Signup and view all the answers

    Which NSAID is specifically contraindicated in patients with sulfa allergies?

    <p>Celecoxib</p> Signup and view all the answers

    What is the main risk that oral NSAIDs pose in patients with bleeding risk?

    <p>GI bleeding</p> Signup and view all the answers

    Which topical NSAID is considered first-line for osteoarthritis?

    <p>Diclofenac</p> Signup and view all the answers

    How often should blood pressure be checked in patients taking oral NSAIDs?

    <p>Every visit</p> Signup and view all the answers

    What is the main reason why celecoxib is recommended for patients with a history of peptic ulcer disease?

    <p>It selectively inhibits COX-2</p> Signup and view all the answers

    Which NSAID should be avoided in patients with long-term anticoagulant use?

    <p>Celecoxib</p> Signup and view all the answers

    What is the recommended frequency for injections for hips?

    <p>Every 6 months</p> Signup and view all the answers

    What is the main concern with increased frequency of injections?

    <p>Risk of cartilage damage</p> Signup and view all the answers

    What is the role of cortisone in pain control?

    <p>It inhibits metalloproteases</p> Signup and view all the answers

    What is the general evidence supporting the use of supplements like glucosamine for osteoarthritis?

    <p>Low evidence</p> Signup and view all the answers

    What is the main purpose of viscosupplementation with hyaluronic acid preparations?

    <p>Mimic normal joint lubrication</p> Signup and view all the answers

    What does the text say about the effectiveness of viscosupplementation with hyaluronic acid preparations?

    <p>Inhibits metalloproteases but has low evidence in general</p> Signup and view all the answers

    When should opiates be considered for osteoarthritis patients according to the text?

    <p>Consider for patients in constant pain and awaiting surgery for a long time</p> Signup and view all the answers

    What is the most significant risk associated with increased frequency of intra-articular injections for osteoarthritis?

    <p>Increased risk of cartilage damage</p> Signup and view all the answers

    Why are opiates generally avoided for osteoarthritis patients?

    <p>Increased likelihood of addiction in patients</p> Signup and view all the answers

    Which factor influences the consideration of tramadol versus T3 (Tylenol with Codeine) for pain management in osteoarthritis patients?

    <p>Severity of pain</p> Signup and view all the answers

    What is a potential justification for the high cost of viscosupplementation with hyaluronic acid preparations?

    <p>Mimicking the natural lubrication of joints</p> Signup and view all the answers

    Why are oral NSAIDs considered risky for patients with a history of ulcers or gastric bleeding?

    <p>Likelihood of worsening ulcers or bleeding</p> Signup and view all the answers

    What is a common difficulty faced by patients considering using supplements like glucosamine for osteoarthritis treatment?

    <p>Lack of scientific evidence supporting their effectiveness</p> Signup and view all the answers

    What is a potential drawback associated with using topical NSAIDs as a first-line treatment for osteoarthritis?

    <p>Potential skin irritation or allergic reactions</p> Signup and view all the answers

    What is a potential risk associated with oral NSAIDs in patients with bleeding risk?

    <p>Gastrointestinal bleeding</p> Signup and view all the answers

    How often should blood pressure be monitored in patients taking oral NSAIDs?

    <p>Every visit</p> Signup and view all the answers

    Which of the following is a contraindication for the use of oral NSAIDs?

    <p>Inflammatory bowel disease (IBD)</p> Signup and view all the answers

    Which topical NSAID is considered first-line for osteoarthritis?

    <p>Diclofenac (Voltaren)</p> Signup and view all the answers

    What is the primary indication for intra-articular injections in osteoarthritis?

    <p>Immediate pain relief</p> Signup and view all the answers

    What is a common recommendation for managing high blood pressure in patients on oral NSAIDs?

    <p>Check blood pressure at every visit</p> Signup and view all the answers

    What are the main risks of using supplements and viscosupplementation for osteoarthritis?

    <p>High blood pressure and renal insufficiency</p> Signup and view all the answers

    Why is acetaminophen still widely used despite its ineffectiveness in osteoarthritis treatment?

    <p>NSAIDs can cause peptic ulcer disease.</p> Signup and view all the answers

    What is a common concern with the long-term use of non-selective NSAIDs in osteoarthritis?

    <p>Increased risk of cardiovascular events.</p> Signup and view all the answers

    Which is a key aspect in the management of the risks associated with oral NSAIDs for osteoarthritis?

    <p>Use of COX-2 selective inhibitors.</p> Signup and view all the answers

    What is the primary reason behind the declining use of acetaminophen for osteoarthritis treatment?

    <p>Acetaminophen's ineffectiveness in reducing pain or improving movement.</p> Signup and view all the answers

    What is a common misconception regarding the use of topical NSAIDs for osteoarthritis?

    <p>They have a higher risk of peptic ulcers compared to oral NSAIDs.</p> Signup and view all the answers

    What is a potential benefit of viscosupplementation with hyaluronic acid preparations for osteoarthritis?

    <p>Improved joint lubrication and shock absorption.</p> Signup and view all the answers

    What is a common misconception about supplements like glucosamine for osteoarthritis management?

    <p>They can cure osteoarthritis completely.</p> Signup and view all the answers

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