Gastrointestinal Risks of NSAIDs Quiz
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Questions and Answers

What type of nonpharmacologic treatments does the American 2019 guidelines recommend for osteoarthritis?

  • Acupuncture
  • Tai chi (correct)
  • Weight lifting
  • Running marathons

Which outcome measure is used to assess treatment efficacy in osteoarthritis according to the text?

  • Blood pressure
  • WOMAC: pain & walking distance (correct)
  • Cholesterol levels
  • BMI

What is the current status of acetaminophen use in osteoarthritis treatment based on the Lancet meta-analysis?

  • It has shown significant benefits in reducing pain and improving movement
  • It is being phased out due to adverse effects
  • It is recommended as a first-line treatment
  • It has no impact on pain management (correct)

What is the primary reason for acetaminophen still being widely used despite its ineffectiveness in osteoarthritis treatment?

<p>Avoidance of COX-1 inhibition and related complications (D)</p> Signup and view all the answers

What is a potential consequence of long-term use of non-selective NSAIDs in osteoarthritis?

<p>Increased risk of peptic ulcer disease (D)</p> Signup and view all the answers

Which pharmacologic treatment is considered a strong recommendation according to the American 2019 guidelines for osteoarthritis?

<p>Topical NSAIDs (D)</p> Signup and view all the answers

Which medication is classified as a weak opiate and conditionally recommended in the American 2019 guidelines for osteoarthritis?

<p>Tramadol (D)</p> Signup and view all the answers

What is the maximum daily dose of indomethacin recommended for gout, ankylosing spondylitis, and psoriatic arthritis?

<p>Up to 150 mg (B)</p> Signup and view all the answers

Which NSAID is specifically contraindicated in patients with sulfa allergies?

<p>Celecoxib (A)</p> Signup and view all the answers

What is the main risk that oral NSAIDs pose in patients with bleeding risk?

<p>GI bleeding (A)</p> Signup and view all the answers

Which topical NSAID is considered first-line for osteoarthritis?

<p>Diclofenac (B)</p> Signup and view all the answers

How often should blood pressure be checked in patients taking oral NSAIDs?

<p>Every visit (A)</p> Signup and view all the answers

What is the main reason why celecoxib is recommended for patients with a history of peptic ulcer disease?

<p>It selectively inhibits COX-2 (C)</p> Signup and view all the answers

Which NSAID should be avoided in patients with long-term anticoagulant use?

<p>Celecoxib (C)</p> Signup and view all the answers

What is the recommended frequency for injections for hips?

<p>Every 6 months (B)</p> Signup and view all the answers

What is the main concern with increased frequency of injections?

<p>Risk of cartilage damage (C)</p> Signup and view all the answers

What is the role of cortisone in pain control?

<p>It inhibits metalloproteases (C)</p> Signup and view all the answers

What is the general evidence supporting the use of supplements like glucosamine for osteoarthritis?

<p>Low evidence (C)</p> Signup and view all the answers

What is the main purpose of viscosupplementation with hyaluronic acid preparations?

<p>Mimic normal joint lubrication (B)</p> Signup and view all the answers

What does the text say about the effectiveness of viscosupplementation with hyaluronic acid preparations?

<p>Inhibits metalloproteases but has low evidence in general (B)</p> Signup and view all the answers

When should opiates be considered for osteoarthritis patients according to the text?

<p>Consider for patients in constant pain and awaiting surgery for a long time (B)</p> Signup and view all the answers

What is the most significant risk associated with increased frequency of intra-articular injections for osteoarthritis?

<p>Increased risk of cartilage damage (C)</p> Signup and view all the answers

Why are opiates generally avoided for osteoarthritis patients?

<p>Increased likelihood of addiction in patients (D)</p> Signup and view all the answers

Which factor influences the consideration of tramadol versus T3 (Tylenol with Codeine) for pain management in osteoarthritis patients?

<p>Severity of pain (C)</p> Signup and view all the answers

What is a potential justification for the high cost of viscosupplementation with hyaluronic acid preparations?

<p>Mimicking the natural lubrication of joints (B)</p> Signup and view all the answers

Why are oral NSAIDs considered risky for patients with a history of ulcers or gastric bleeding?

<p>Likelihood of worsening ulcers or bleeding (C)</p> Signup and view all the answers

What is a common difficulty faced by patients considering using supplements like glucosamine for osteoarthritis treatment?

<p>Lack of scientific evidence supporting their effectiveness (D)</p> Signup and view all the answers

What is a potential drawback associated with using topical NSAIDs as a first-line treatment for osteoarthritis?

<p>Potential skin irritation or allergic reactions (A)</p> Signup and view all the answers

What is a potential risk associated with oral NSAIDs in patients with bleeding risk?

<p>Gastrointestinal bleeding (B)</p> Signup and view all the answers

How often should blood pressure be monitored in patients taking oral NSAIDs?

<p>Every visit (B)</p> Signup and view all the answers

Which of the following is a contraindication for the use of oral NSAIDs?

<p>Inflammatory bowel disease (IBD) (D)</p> Signup and view all the answers

Which topical NSAID is considered first-line for osteoarthritis?

<p>Diclofenac (Voltaren) (A)</p> Signup and view all the answers

What is the primary indication for intra-articular injections in osteoarthritis?

<p>Immediate pain relief (C)</p> Signup and view all the answers

What is a common recommendation for managing high blood pressure in patients on oral NSAIDs?

<p>Check blood pressure at every visit (B)</p> Signup and view all the answers

What are the main risks of using supplements and viscosupplementation for osteoarthritis?

<p>High blood pressure and renal insufficiency (B)</p> Signup and view all the answers

Why is acetaminophen still widely used despite its ineffectiveness in osteoarthritis treatment?

<p>NSAIDs can cause peptic ulcer disease. (C)</p> Signup and view all the answers

What is a common concern with the long-term use of non-selective NSAIDs in osteoarthritis?

<p>Increased risk of cardiovascular events. (B)</p> Signup and view all the answers

Which is a key aspect in the management of the risks associated with oral NSAIDs for osteoarthritis?

<p>Use of COX-2 selective inhibitors. (A)</p> Signup and view all the answers

What is the primary reason behind the declining use of acetaminophen for osteoarthritis treatment?

<p>Acetaminophen's ineffectiveness in reducing pain or improving movement. (D)</p> Signup and view all the answers

What is a common misconception regarding the use of topical NSAIDs for osteoarthritis?

<p>They have a higher risk of peptic ulcers compared to oral NSAIDs. (B)</p> Signup and view all the answers

What is a potential benefit of viscosupplementation with hyaluronic acid preparations for osteoarthritis?

<p>Improved joint lubrication and shock absorption. (A)</p> Signup and view all the answers

What is a common misconception about supplements like glucosamine for osteoarthritis management?

<p>They can cure osteoarthritis completely. (B)</p> Signup and view all the answers

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