42 Questions
What type of nonpharmacologic treatments does the American 2019 guidelines recommend for osteoarthritis?
Tai chi
Which outcome measure is used to assess treatment efficacy in osteoarthritis according to the text?
WOMAC: pain & walking distance
What is the current status of acetaminophen use in osteoarthritis treatment based on the Lancet meta-analysis?
It has no impact on pain management
What is the primary reason for acetaminophen still being widely used despite its ineffectiveness in osteoarthritis treatment?
Avoidance of COX-1 inhibition and related complications
What is a potential consequence of long-term use of non-selective NSAIDs in osteoarthritis?
Increased risk of peptic ulcer disease
Which pharmacologic treatment is considered a strong recommendation according to the American 2019 guidelines for osteoarthritis?
Topical NSAIDs
Which medication is classified as a weak opiate and conditionally recommended in the American 2019 guidelines for osteoarthritis?
Tramadol
What is the maximum daily dose of indomethacin recommended for gout, ankylosing spondylitis, and psoriatic arthritis?
Up to 150 mg
Which NSAID is specifically contraindicated in patients with sulfa allergies?
Celecoxib
What is the main risk that oral NSAIDs pose in patients with bleeding risk?
GI bleeding
Which topical NSAID is considered first-line for osteoarthritis?
Diclofenac
How often should blood pressure be checked in patients taking oral NSAIDs?
Every visit
What is the main reason why celecoxib is recommended for patients with a history of peptic ulcer disease?
It selectively inhibits COX-2
Which NSAID should be avoided in patients with long-term anticoagulant use?
Celecoxib
What is the recommended frequency for injections for hips?
Every 6 months
What is the main concern with increased frequency of injections?
Risk of cartilage damage
What is the role of cortisone in pain control?
It inhibits metalloproteases
What is the general evidence supporting the use of supplements like glucosamine for osteoarthritis?
Low evidence
What is the main purpose of viscosupplementation with hyaluronic acid preparations?
Mimic normal joint lubrication
What does the text say about the effectiveness of viscosupplementation with hyaluronic acid preparations?
Inhibits metalloproteases but has low evidence in general
When should opiates be considered for osteoarthritis patients according to the text?
Consider for patients in constant pain and awaiting surgery for a long time
What is the most significant risk associated with increased frequency of intra-articular injections for osteoarthritis?
Increased risk of cartilage damage
Why are opiates generally avoided for osteoarthritis patients?
Increased likelihood of addiction in patients
Which factor influences the consideration of tramadol versus T3 (Tylenol with Codeine) for pain management in osteoarthritis patients?
Severity of pain
What is a potential justification for the high cost of viscosupplementation with hyaluronic acid preparations?
Mimicking the natural lubrication of joints
Why are oral NSAIDs considered risky for patients with a history of ulcers or gastric bleeding?
Likelihood of worsening ulcers or bleeding
What is a common difficulty faced by patients considering using supplements like glucosamine for osteoarthritis treatment?
Lack of scientific evidence supporting their effectiveness
What is a potential drawback associated with using topical NSAIDs as a first-line treatment for osteoarthritis?
Potential skin irritation or allergic reactions
What is a potential risk associated with oral NSAIDs in patients with bleeding risk?
Gastrointestinal bleeding
How often should blood pressure be monitored in patients taking oral NSAIDs?
Every visit
Which of the following is a contraindication for the use of oral NSAIDs?
Inflammatory bowel disease (IBD)
Which topical NSAID is considered first-line for osteoarthritis?
Diclofenac (Voltaren)
What is the primary indication for intra-articular injections in osteoarthritis?
Immediate pain relief
What is a common recommendation for managing high blood pressure in patients on oral NSAIDs?
Check blood pressure at every visit
What are the main risks of using supplements and viscosupplementation for osteoarthritis?
High blood pressure and renal insufficiency
Why is acetaminophen still widely used despite its ineffectiveness in osteoarthritis treatment?
NSAIDs can cause peptic ulcer disease.
What is a common concern with the long-term use of non-selective NSAIDs in osteoarthritis?
Increased risk of cardiovascular events.
Which is a key aspect in the management of the risks associated with oral NSAIDs for osteoarthritis?
Use of COX-2 selective inhibitors.
What is the primary reason behind the declining use of acetaminophen for osteoarthritis treatment?
Acetaminophen's ineffectiveness in reducing pain or improving movement.
What is a common misconception regarding the use of topical NSAIDs for osteoarthritis?
They have a higher risk of peptic ulcers compared to oral NSAIDs.
What is a potential benefit of viscosupplementation with hyaluronic acid preparations for osteoarthritis?
Improved joint lubrication and shock absorption.
What is a common misconception about supplements like glucosamine for osteoarthritis management?
They can cure osteoarthritis completely.
Test your knowledge on the gastrointestinal risks associated with NSAIDs, including ulcerations, bleeds, and decreased platelet activity. Learn about the recommended daily dosages for ibuprofen, naproxen, and diclofenac, as well as alternative options for individuals with specific risk factors.
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