Gastrointestinal Protection and Antacids

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Which antacid forms aluminum chloride in the stomach and gradually adsorbs pepsin?

Magnesium Hydroxide

Aluminum Hydroxide (correct)

Calcium carbonate

Magnesium trisilicate

What is the role of alginates in the treatment of GERD?

Increase mucus viscosity and adherence to the esophageal mucosa (correct)

Prevent bloating and flatulence

Increase blood flow

Eradicate Helicobacter pylori

Which antacid is known for being potent and rapid-acting?

Magnesium trisilicate

Calcium carbonate (correct)

Aluminum Hydroxide

Magnesium Hydroxide

What is the clinical importance of taking antacids 2 hours before or after ingestion of other drugs?

To avoid interactions with drugs by adsorbing and forming insoluble complexes Signup and view all the answers

What is the primary function of Simethicone in the digestive system?

Prevent 'foaming' to relieve bloating and flatulence Signup and view all the answers

How does magnesium trisilicate act in the stomach?

Reacts slowly with gastric juice to form magnesium chloride and colloidal silica Signup and view all the answers

Which of the following is NOT a common additive in antacids?

Helicobacter pylori Signup and view all the answers

What effect does magnesium hydroxide have in the stomach?

Increases mucus & HCO3- secretion Signup and view all the answers

What is the gradual action of Aluminum Hydroxide in the stomach due to?

Formation of aluminum chloride Signup and view all the answers

What is the key role of calcium carbonate as an antacid?

Rapidly acting on stomach acid Signup and view all the answers

Which of the following is the most effective triple therapy regimen for the treatment of Helicobacter pylori infection?

Omeprazole/Lansoprazole, Metronidazole/Clarithromycin, and Amoxicillin given for 14 days, followed by a PPI for 4-6 weeks Signup and view all the answers

How do proton pump inhibitors (PPIs) promote Helicobacter pylori eradication?

By lowering the intragastric pH, which increases the efficacy of antimicrobial agents Signup and view all the answers

What is the mechanism of action of sucralfate in the treatment of gastric ulcers?

It forms a viscous gel that adheres to the ulcer crater, protecting it from further damage Signup and view all the answers

What is the primary mechanism of action of misoprostol in the prevention of NSAID-induced ulcers?

It stimulates the secretion of mucus and bicarbonate, and enhances mucosal blood flow Signup and view all the answers

Which of the following statements about colloidal bismuth compounds is correct?

They have direct antimicrobial properties against Helicobacter pylori Signup and view all the answers

Which of the following is a common side effect of misoprostol?

Diarrhea and abdominal cramping Signup and view all the answers

What is the primary mechanism of action of histamine-2 (H2) receptor antagonists in the treatment of gastric ulcers?

They inhibit the production of stomach acid Signup and view all the answers

Which of the following statements about proton pump inhibitors (PPIs) is correct?

They inhibit the production of stomach acid by blocking the final step in the acid secretion pathway Signup and view all the answers

Which of the following statements about antimicrobial agents used in the treatment of Helicobacter pylori infection is correct?

They have direct antimicrobial properties against H. pylori Signup and view all the answers