Gastrointestinal Protection and Antacids
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Questions and Answers

Which antacid forms aluminum chloride in the stomach and gradually adsorbs pepsin?

  • Magnesium Hydroxide
  • Aluminum Hydroxide (correct)
  • Calcium carbonate
  • Magnesium trisilicate
  • What is the role of alginates in the treatment of GERD?

  • Increase mucus viscosity and adherence to the esophageal mucosa (correct)
  • Prevent bloating and flatulence
  • Increase blood flow
  • Eradicate Helicobacter pylori
  • Which antacid is known for being potent and rapid-acting?

  • Magnesium trisilicate
  • Calcium carbonate (correct)
  • Aluminum Hydroxide
  • Magnesium Hydroxide
  • What is the clinical importance of taking antacids 2 hours before or after ingestion of other drugs?

    <p>To avoid interactions with drugs by adsorbing and forming insoluble complexes</p> Signup and view all the answers

    What is the primary function of Simethicone in the digestive system?

    <p>Prevent 'foaming' to relieve bloating and flatulence</p> Signup and view all the answers

    How does magnesium trisilicate act in the stomach?

    <p>Reacts slowly with gastric juice to form magnesium chloride and colloidal silica</p> Signup and view all the answers

    Which of the following is NOT a common additive in antacids?

    <p>Helicobacter pylori</p> Signup and view all the answers

    What effect does magnesium hydroxide have in the stomach?

    <p>Increases mucus &amp; HCO3- secretion</p> Signup and view all the answers

    What is the gradual action of Aluminum Hydroxide in the stomach due to?

    <p>Formation of aluminum chloride</p> Signup and view all the answers

    What is the key role of calcium carbonate as an antacid?

    <p>Rapidly acting on stomach acid</p> Signup and view all the answers

    Which of the following is the most effective triple therapy regimen for the treatment of Helicobacter pylori infection?

    <p>Omeprazole/Lansoprazole, Metronidazole/Clarithromycin, and Amoxicillin given for 14 days, followed by a PPI for 4-6 weeks</p> Signup and view all the answers

    How do proton pump inhibitors (PPIs) promote Helicobacter pylori eradication?

    <p>By lowering the intragastric pH, which increases the efficacy of antimicrobial agents</p> Signup and view all the answers

    What is the mechanism of action of sucralfate in the treatment of gastric ulcers?

    <p>It forms a viscous gel that adheres to the ulcer crater, protecting it from further damage</p> Signup and view all the answers

    What is the primary mechanism of action of misoprostol in the prevention of NSAID-induced ulcers?

    <p>It stimulates the secretion of mucus and bicarbonate, and enhances mucosal blood flow</p> Signup and view all the answers

    Which of the following statements about colloidal bismuth compounds is correct?

    <p>They have direct antimicrobial properties against Helicobacter pylori</p> Signup and view all the answers

    Which of the following is a common side effect of misoprostol?

    <p>Diarrhea and abdominal cramping</p> Signup and view all the answers

    What is the primary mechanism of action of histamine-2 (H2) receptor antagonists in the treatment of gastric ulcers?

    <p>They inhibit the production of stomach acid</p> Signup and view all the answers

    Which of the following statements about proton pump inhibitors (PPIs) is correct?

    <p>They inhibit the production of stomach acid by blocking the final step in the acid secretion pathway</p> Signup and view all the answers

    Which of the following statements about antimicrobial agents used in the treatment of Helicobacter pylori infection is correct?

    <p>They have direct antimicrobial properties against H. pylori</p> Signup and view all the answers

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