Gastrointestinal Protection and Antacids
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Questions and Answers

Which antacid forms aluminum chloride in the stomach and gradually adsorbs pepsin?

  • Magnesium Hydroxide
  • Aluminum Hydroxide (correct)
  • Calcium carbonate
  • Magnesium trisilicate

What is the role of alginates in the treatment of GERD?

  • Increase mucus viscosity and adherence to the esophageal mucosa (correct)
  • Prevent bloating and flatulence
  • Increase blood flow
  • Eradicate Helicobacter pylori

Which antacid is known for being potent and rapid-acting?

  • Magnesium trisilicate
  • Calcium carbonate (correct)
  • Aluminum Hydroxide
  • Magnesium Hydroxide

What is the clinical importance of taking antacids 2 hours before or after ingestion of other drugs?

<p>To avoid interactions with drugs by adsorbing and forming insoluble complexes (C)</p> Signup and view all the answers

What is the primary function of Simethicone in the digestive system?

<p>Prevent 'foaming' to relieve bloating and flatulence (A)</p> Signup and view all the answers

How does magnesium trisilicate act in the stomach?

<p>Reacts slowly with gastric juice to form magnesium chloride and colloidal silica (B)</p> Signup and view all the answers

Which of the following is NOT a common additive in antacids?

<p>Helicobacter pylori (B)</p> Signup and view all the answers

What effect does magnesium hydroxide have in the stomach?

<p>Increases mucus &amp; HCO3- secretion (A)</p> Signup and view all the answers

What is the gradual action of Aluminum Hydroxide in the stomach due to?

<p>Formation of aluminum chloride (A)</p> Signup and view all the answers

What is the key role of calcium carbonate as an antacid?

<p>Rapidly acting on stomach acid (B)</p> Signup and view all the answers

Which of the following is the most effective triple therapy regimen for the treatment of Helicobacter pylori infection?

<p>Omeprazole/Lansoprazole, Metronidazole/Clarithromycin, and Amoxicillin given for 14 days, followed by a PPI for 4-6 weeks (D)</p> Signup and view all the answers

How do proton pump inhibitors (PPIs) promote Helicobacter pylori eradication?

<p>By lowering the intragastric pH, which increases the efficacy of antimicrobial agents (D)</p> Signup and view all the answers

What is the mechanism of action of sucralfate in the treatment of gastric ulcers?

<p>It forms a viscous gel that adheres to the ulcer crater, protecting it from further damage (A)</p> Signup and view all the answers

What is the primary mechanism of action of misoprostol in the prevention of NSAID-induced ulcers?

<p>It stimulates the secretion of mucus and bicarbonate, and enhances mucosal blood flow (C)</p> Signup and view all the answers

Which of the following statements about colloidal bismuth compounds is correct?

<p>They have direct antimicrobial properties against Helicobacter pylori (C)</p> Signup and view all the answers

Which of the following is a common side effect of misoprostol?

<p>Diarrhea and abdominal cramping (B)</p> Signup and view all the answers

What is the primary mechanism of action of histamine-2 (H2) receptor antagonists in the treatment of gastric ulcers?

<p>They inhibit the production of stomach acid (B)</p> Signup and view all the answers

Which of the following statements about proton pump inhibitors (PPIs) is correct?

<p>They inhibit the production of stomach acid by blocking the final step in the acid secretion pathway (D)</p> Signup and view all the answers

Which of the following statements about antimicrobial agents used in the treatment of Helicobacter pylori infection is correct?

<p>They have direct antimicrobial properties against H. pylori (D)</p> Signup and view all the answers

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