Gastrointestinal Disease Quiz
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Questions and Answers

How do antacids primarily work in the context of mucosal cytoprotection?

  • By neutralizing acid (correct)
  • By increasing acid production
  • By enhancing mucosal damage
  • By preventing acid secretion
  • Why is a proton pump inhibitor considered more practical than antacids in the given context?

  • They do not interfere with Q-Tc interval (correct)
  • They neutralize acid faster
  • They have fewer side effects
  • They are better absorbed in the small intestine
  • What is the role of endoscopy in diagnosing a duodenal ulcer in young patients with Helicobacter pylori antibodies?

  • Only used for follow-up
  • Essential for diagnosis
  • Not necessary (correct)
  • Used for symptom relief
  • Why are good double-contrast barium meals becoming less frequent compared to endoscopy?

    <p>Biopsies cannot be taken with them</p> Signup and view all the answers

    Which macrolide is recommended to stick to until new evidence arises regarding H.pylori eradication regimens?

    <p>Clarithromycin</p> Signup and view all the answers

    How does omeprazole's formulation as enteric-coated granules affect its absorption?

    <p>No effect on its absorption</p> Signup and view all the answers

    What is the usual long-term treatment for patients who require long-term treatment for gastrointestinal disease?

    <p>H2-receptor antagonist or proton pump inhibitor</p> Signup and view all the answers

    What is the effect of smoking on peptic ulcer disease and gastro-oesophageal reflux according to the text?

    <p>Impairs healing and worsens reflux</p> Signup and view all the answers

    What is the cause of belching according to the text?

    <p>Swallowing air</p> Signup and view all the answers

    Why do patients with reflux oesophagitis usually have a low lower oesophageal sphincter pressure?

    <p>Permanent event of reflux</p> Signup and view all the answers

    What is the role of highly selective vagotomy in treating acid-related diseases according to the text?

    <p>Reduces acid output effectively</p> Signup and view all the answers

    Why are gastric ulcers more common on the lesser curve according to the text?

    <p>Unknown definitive reason</p> Signup and view all the answers

    What is the recommended treatment for mild reflux oesophagitis in young patients to prevent the development of Barrett’s oesophagitis?

    <p>Short-term proton pump inhibitors (PPIs)</p> Signup and view all the answers

    How does Barrett’s oesophagus typically develop?

    <p>From chronic gastroesophageal reflux disease (GERD)</p> Signup and view all the answers

    Is it safe to give a patient with reflux oesophagitis, who is on proton pump inhibitors (PPIs), aspirin in antiplatelet doses?

    <p>No, it is not safe</p> Signup and view all the answers

    Does a combination of magnesium and aluminium hydroxide salts, used as antacids for reflux oesophagitis, have serious long-term adverse effects?

    <p>No, it does not have serious long-term adverse effects</p> Signup and view all the answers

    In the treatment of reflux oesophagitis with a proton pump inhibitor (PPI), should the PPI be given for life or for a specific duration?

    <p>Short-term PPI treatment (4–8 weeks)</p> Signup and view all the answers

    Is it recommended to treat asymptomatic endoscopically diagnosed reflux oesophagitis with acid suppression and/or antireflux measures?

    <p>No, it is not recommended</p> Signup and view all the answers

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