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Gastric Pathogenesis Quiz: CD4+ T cells and Pernicious Anemia

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Gastric Pathogenesis Quiz: CD4+ T cells and Pernicious Anemia

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Questions and Answers

What are the possible routes of transmission for the microbe causing chronic gastritis and peptic ulcers?

Respiratory, bloodborne, sexual

Oral-oral, fecal-oral, environmental (correct)

Vector-borne, waterborne, vertical transmission

Direct contact, airborne, foodborne

Which virulence factor of the microbe plays a role in its ability to survive in the gastric environment?

Resistance to antibiotics

Production of spores

Motility via flagella (correct)

Ability to form biofilms

Which type of inflammatory cells are typically found in the lamina propria in chronic gastritis?

B lymphocytes

Neutrophils (correct)

Macrophages

Eosinophils

What is the pattern of gastritis associated with duodenal ulcers?

Antral with high acid production (C) Signup and view all the answers

What is the main risk factor for adenocarcinoma in patients with chronic gastritis?

Intestinal metaplasia (D) Signup and view all the answers

What is a potential cause of acute gastritis based on the provided information?

Increased acid secretion (C) Signup and view all the answers

Which factor is NOT associated with the pathogenesis of acute gastritis?

Increased bicarbonate secretion (A) Signup and view all the answers

What may frequently accompany acute gastritis according to the text?

Peptic ulcer disease (B) Signup and view all the answers

Which of the following is NOT a potential cause of acute gastritis based on the text?

Enhanced blood flow (D) Signup and view all the answers

What is a possible consequence of direct epithelial damage in acute gastritis?

Disruption of adherent mucus layer (D) Signup and view all the answers

What is the pathogenesis of pernicious anemia in autoimmune gastritis?

Intrinsic factor deficiency due to hyperplasia of antral gastrin-producing G cells (B) Signup and view all the answers

Which cell type is primarily targeted by CD4+ T cells in autoimmune gastritis?

Parietal cells (D) Signup and view all the answers

What is a characteristic endoscopic feature of autoimmune gastritis?

Coarser rugae than normal in the affected regions (B) Signup and view all the answers

Which condition is associated with hypergastrinemia as a consequence of autoimmune gastritis?

Peptic ulcer disease (D) Signup and view all the answers

In autoimmune gastritis, what happens due to the lack of intrinsic factor?

Onset of pernicious anemia (C) Signup and view all the answers