Gastric Pathogenesis Quiz: CD4+ T cells and Pernicious Anemia
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Questions and Answers

What are the possible routes of transmission for the microbe causing chronic gastritis and peptic ulcers?

  • Respiratory, bloodborne, sexual
  • Oral-oral, fecal-oral, environmental (correct)
  • Vector-borne, waterborne, vertical transmission
  • Direct contact, airborne, foodborne
  • Which virulence factor of the microbe plays a role in its ability to survive in the gastric environment?

  • Resistance to antibiotics
  • Production of spores
  • Motility via flagella (correct)
  • Ability to form biofilms
  • Which type of inflammatory cells are typically found in the lamina propria in chronic gastritis?

  • B lymphocytes
  • Neutrophils (correct)
  • Macrophages
  • Eosinophils
  • What is the pattern of gastritis associated with duodenal ulcers?

    <p>Antral with high acid production</p> Signup and view all the answers

    What is the main risk factor for adenocarcinoma in patients with chronic gastritis?

    <p>Intestinal metaplasia</p> Signup and view all the answers

    What is a potential cause of acute gastritis based on the provided information?

    <p>Increased acid secretion</p> Signup and view all the answers

    Which factor is NOT associated with the pathogenesis of acute gastritis?

    <p>Increased bicarbonate secretion</p> Signup and view all the answers

    What may frequently accompany acute gastritis according to the text?

    <p>Peptic ulcer disease</p> Signup and view all the answers

    Which of the following is NOT a potential cause of acute gastritis based on the text?

    <p>Enhanced blood flow</p> Signup and view all the answers

    What is a possible consequence of direct epithelial damage in acute gastritis?

    <p>Disruption of adherent mucus layer</p> Signup and view all the answers

    What is the pathogenesis of pernicious anemia in autoimmune gastritis?

    <p>Intrinsic factor deficiency due to hyperplasia of antral gastrin-producing G cells</p> Signup and view all the answers

    Which cell type is primarily targeted by CD4+ T cells in autoimmune gastritis?

    <p>Parietal cells</p> Signup and view all the answers

    What is a characteristic endoscopic feature of autoimmune gastritis?

    <p>Coarser rugae than normal in the affected regions</p> Signup and view all the answers

    Which condition is associated with hypergastrinemia as a consequence of autoimmune gastritis?

    <p>Peptic ulcer disease</p> Signup and view all the answers

    In autoimmune gastritis, what happens due to the lack of intrinsic factor?

    <p>Onset of pernicious anemia</p> Signup and view all the answers

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