5 Questions
Where is Gastric Inhibitory Peptide (GIP) produced?
By K cells in the mucosa of the duodenum and jejunum
What stimulates the secretion of Gastric Inhibitory Peptide (GIP)?
Glucose and fat in the duodenum
What is another name for Gastric Inhibitory Peptide (GIP)?
Glucose-dependent insulinotropic peptide
What is the effect of Gastric Inhibitory Peptide (GIP) on gastric secretion and motility?
Inhibits gastric secretion and motility
Which hormones, besides GIP, stimulate insulin secretion?
Gastrin, CCK, secretin, and glucagon
Study Notes
Gastric Inhibitory Peptide (GIP)
- Produced by K cells in the mucosa of the duodenum and jejunum.
- Secretion is stimulated by glucose and fat in the duodenum.
- In large doses, it inhibits gastric secretion and motility.
- Stimulates insulin secretion, similar to gastrin, CCK, secretin, and glucagon.
- The only one of these that stimulates insulin secretion at blood levels comparable to those produced by oral glucose.
- Often called glucose-dependent insulinotropic peptide (GIP) due to its ability to stimulate insulin secretion in response to oral glucose.
Learn about Gastric Inhibitory Peptide (GIP) production, secretion stimulation, and its effects on gastric secretion, motility, and insulin secretion.
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