Gas Transport and pH Introduction

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Questions and Answers

What is the primary mechanism that allows oxygen to cross the alveoli and re-oxygenate the blood in the pulmonary vasculature?

  • Diffusion (correct)
  • Active transport
  • Osmosis
  • Facilitated diffusion

What percentage of oxygen that dissolves in the blood combines with the oxygen-carrying protein hemoglobin?

  • 99% (correct)
  • 85%
  • 90%
  • 95%

What is the primary factor that determines the delivery of oxygen to a particular tissue?

  • Cardiac output
  • Arterial oxygen concentration
  • Oxygen entering the lungs
  • All of the above (correct)

What is the term for the volume of oxygen delivered to the systemic vascular bed per minute?

<p>Oxygen delivery (A)</p> Signup and view all the answers

What is the direction of flow of oxygen and carbon dioxide in the lung?

<p>From higher to lower partial pressures (C)</p> Signup and view all the answers

What is the percentage of CO2 that dissolves in the blood and enters into a series of reversible chemical reactions?

<p>94.5% (B)</p> Signup and view all the answers

What two systems are necessary for the ability to deliver oxygen in the body?

<p>Respiratory and circulatory (D)</p> Signup and view all the answers

What happens to the curve when there is a rise in temperature or a fallen pH?

<p>It shifts to the right (D)</p> Signup and view all the answers

What is the significance of p50 in relation to hemoglobin and O2 binding?

<p>It is the pO2 at which hemoglobin is half saturated with O2 (C)</p> Signup and view all the answers

What is the minimum concentration of reduced hemoglobin required for cyanosis to appear?

<p>5 g/dL (A)</p> Signup and view all the answers

What is the term for the bluish discoloration of the tissues due to reduced hemoglobin?

<p>Cyanosis (B)</p> Signup and view all the answers

What is the effect of a fallen temperature on the O2 dissociation curve?

<p>It shifts the curve to the left (C)</p> Signup and view all the answers

What determines the occurrence of cyanosis?

<p>The total amount of hemoglobin, the degree of hemoglobin unsaturation, and the state of the capillary circulation (C)</p> Signup and view all the answers

What is the significance of a higher p50 value?

<p>It indicates a lower affinity of hemoglobin for O2 (D)</p> Signup and view all the answers

What is the primary function of increased myoglobin in high-altitude adaptation?

<p>To facilitate the movement of oxygen into the tissues (A)</p> Signup and view all the answers

What is the characteristic of the natives who live in high-altitude villages?

<p>They are remarkably normal with low alveolar po2 values (A)</p> Signup and view all the answers

What is the purpose of carbon monoxide in the body?

<p>It functions as a chemical messenger in the brain and elsewhere (D)</p> Signup and view all the answers

What is the result of incomplete combustion of carbon outside the body?

<p>The formation of carbon monoxide (C)</p> Signup and view all the answers

What is the significance of the existence of permanent human habitations in the Andes and Himalayas at elevations above 5,500 m?

<p>It indicates the effectiveness of the acclimatization process (D)</p> Signup and view all the answers

What is the characteristics of the chest of natives who live in high-altitude villages?

<p>They are barrel-chested (D)</p> Signup and view all the answers

What is the historical use of carbon monoxide?

<p>As a method of execution (A)</p> Signup and view all the answers

What is the primary reason why CO poisoning has become less common in the United States?

<p>Increased use of natural gas (D)</p> Signup and view all the answers

What is the name of the compound formed when CO reacts with hemoglobin?

<p>Carboxyhemoglobin (COHb) (C)</p> Signup and view all the answers

Why is CO poisoning considered a form of anemic hypoxia?

<p>Because CO reduces the amount of hemoglobin available for O2 transport (D)</p> Signup and view all the answers

What is the approximate ratio of the affinity of hemoglobin for CO to its affinity for O2?

<p>210 times (C)</p> Signup and view all the answers

Why does the presence of COHb shift the dissociation curve of HbO2 to the left?

<p>Because COHb decreases the amount of O2 released from HbO2 (B)</p> Signup and view all the answers

Why is oxygen treatment of limited value in hypoperfusion, anemic, and histotoxic hypoxia?

<p>Because it can only increase the amount of dissolved oxygen in the arterial blood (D)</p> Signup and view all the answers

In which type of hypoxia is oxygen treatment of great benefit?

<p>Other forms of hypoxia (C)</p> Signup and view all the answers

What is the effect of COHb on the amount of hemoglobin available for O2 transport?

<p>It decreases the amount of hemoglobin available for O2 transport (A)</p> Signup and view all the answers

Why is an individual with 50% of the normal amount of HbO2 incapacitated by the formation of COHb?

<p>Because they already have a low amount of hemoglobin available for O2 transport (A)</p> Signup and view all the answers

What is the effect of CO on the transport of O2 in the blood?

<p>It reduces the amount of O2 transported in the blood (D)</p> Signup and view all the answers

Which type of hypoxia is characterized by a normal arterial PO2 but a reduced amount of hemoglobin available to carry oxygen?

<p>Anemic hypoxia (B)</p> Signup and view all the answers

What is the term sometimes used to describe Hypoxemia?

<p>Hypoxic hypoxia (A)</p> Signup and view all the answers

What is the primary effect of histotoxic hypoxia on tissues?

<p>Inhibited oxygen utilization by tissue cells (B)</p> Signup and view all the answers

How long does it take for the increase in circulating red blood cells to begin after ascent to high altitude?

<p>In 2-3 days (A)</p> Signup and view all the answers

What is the response to high altitude that leads to a decrease in erythropoietin secretion?

<p>Increased ventilatory response (C)</p> Signup and view all the answers

What is the term that is a more correct description of a condition with low oxygen levels in the tissues?

<p>Hypoxia (C)</p> Signup and view all the answers

What occurs in the tissues in response to hypoxia, besides the increase in circulating red blood cells?

<p>Compensatory changes (D)</p> Signup and view all the answers

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