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Gabapentin Overview and Pharmacology

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Questions and Answers

What category class does Gabapentin (Neurontin) belong to?

Antidepressants
Analgesics
Anticonvulsants (correct)
Mood Stabilizers (correct)

What is the expected pharmacological action of Gabapentin?

Mechanism of action is not known. May affect transport of amino acids across and stabilize neuronal membranes.

What is the therapeutic use of Gabapentin?

Decreased incidence of seizures.

Which of the following are contraindications or precautions for Gabapentin?

<p>Hypersensitivity (A), Use cautiously in all patients (B), Renal insufficiency (C)</p> Signup and view all the answers

Study Notes

Gabapentin Overview

Gabapentin, marketed as Neurontin, falls under the category of anticonvulsants and mood stabilizers.

Pharmacological Action

The exact mechanism of action for gabapentin is unknown.
It may influence the transport of amino acids and help stabilize neuronal membranes.

Therapeutic Applications

Primarily used to reduce the frequency of seizures in patients.

Contraindications and Precautions

Contraindicated for individuals with hypersensitivity to the drug.
Requires caution in all patients due to potential increased risk of suicidal thoughts and behaviors.
Special care is necessary for patients with renal insufficiency, as dosage adjustments are needed for those with creatinine clearance (CCr) less than or equal to 60 mL/min.
Safety during pregnancy and lactation has not been established.
Use is not recommended for children without careful consideration.

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Description

This quiz covers the overview, pharmacological actions, and therapeutic applications of gabapentin, also known as Neurontin. It also outlines the contraindications and precautions necessary for its use in various patient populations, providing a comprehensive look at this anticonvulsant and mood stabilizer.