Gabapentin

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Questions and Answers

Which medication has the longest duration of action among the NSAIDs mentioned?

  • Ketorolac
  • Ibuprofen
  • Diclofenac
  • Naproxen (correct)

What is the recommended dosing interval for Ketorolac in patients with a creatinine clearance (CrCl) of 10-50 mL/min?

  • Every 4 hours
  • Every 8 hours
  • Every 12 hours
  • Every 6 hours (correct)

Which medication should be avoided in patients with significant liver disease?

  • Naproxen
  • Ibuprofen
  • Ketorolac
  • Diclofenac (correct)

Which medication is safer for use in pregnancy and breastfeeding?

<p>Ibuprofen (B)</p> Signup and view all the answers

Which of the following is NOT a pharmacologic agent that works on mu receptors?

<p>Codeine (B)</p> Signup and view all the answers

Which opioid receptor is associated with dysphoria and psychosis?

<p>Kappa (B)</p> Signup and view all the answers

Which opioid medication is classified as a partial agonist?

<p>Buprenorphine (A)</p> Signup and view all the answers

Which opioid medication is recommended to be co-prescribed with chronic opioids?

<p>Naloxone (B)</p> Signup and view all the answers

Which of the following is the maximum daily dose of Naproxen (ER)?

<p>4 g (D)</p> Signup and view all the answers

What is the maximum daily dose of Naproxen Sodium (IR)?

<p>660 mg (C)</p> Signup and view all the answers

What is the maximum daily dose of OTC Ibuprofen?

<p>1.2 g (D)</p> Signup and view all the answers

What is the maximum daily dose of Naproxen Sodium (OTC)?

<p>220 mg (C)</p> Signup and view all the answers

Which of the following is a potential adverse effect of opioids?

<p>Constipation (B)</p> Signup and view all the answers

What is the purpose of reducing the dose by 50% when switching between opioids?

<p>To reduce the risk of adverse effects (C)</p> Signup and view all the answers

What is the correct formula to calculate the total daily dose (TDD) of an opioid?

<p>TDD = (Analgesic dose) / (Dosing interval) (A)</p> Signup and view all the answers

Which opioid is commonly used as an adjunct in general anesthesia or in severe acute pain, and may be used in patients with a true allergy to morphine?

<p>Fentanyl (B)</p> Signup and view all the answers

Which opioid is the gold standard for pain management and is an excellent and cost-effective first choice for severe acute and chronic pain?

<p>Morphine (A)</p> Signup and view all the answers

Which opioid has a higher potential for abuse and is not more effective than other opioids?

<p>Oxycodone (A)</p> Signup and view all the answers

Which opioid is more potent than morphine and is commonly prescribed in its immediate-release form in combination with APAP?

<p>Hydromorphone (C)</p> Signup and view all the answers

Which of the following is a common side effect of Tramadol?

<p>Increased heart rate (C)</p> Signup and view all the answers

What is the mechanism of action of Tramadol in treating neuropathic pain?

<p>Activation of opioid receptors (C)</p> Signup and view all the answers

Which of the following is a commonly used topical analgesic for neuropathic pain?

<p>Lidocaine (C)</p> Signup and view all the answers

Which medication is FDA approved for diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia?

<p>Pregabalin (D)</p> Signup and view all the answers

Which of the following is a side effect of tricyclic antidepressants?

<p>Dry mouth (D)</p> Signup and view all the answers

Which of the following is an FDA-approved agent for the treatment of fibromyalgia?

<p>Duloxetine (C)</p> Signup and view all the answers

Which type of pain is most commonly associated with cancer?

<p>Bone pain (C)</p> Signup and view all the answers

Which of the following is a goal of cancer-related pain treatment?

<p>Optimal function and comfort (C)</p> Signup and view all the answers

Which drug is FDA approved for post-herpetic neuralgia and restless leg syndrome?

<p>Gabapentin ER (B)</p> Signup and view all the answers

Which drug has similar efficacy to pregabalin and TCAs, and can be combined with lidocaine, capsaicin, TCA, and SNRI?

<p>Gabapentin IR (D)</p> Signup and view all the answers

Which drug is effective for diabetic neuropathic pain, post-herpetic neuralgia, trigeminal neuralgia, restless leg syndrome, hot flashes, and alcohol dependence?

<p>Gabapentin IR (C)</p> Signup and view all the answers

Which drug is useful in pain states for patients with or without depression, effective for neuropathic pain, and inexpensive?

<p>Venlafaxine (B)</p> Signup and view all the answers

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