GABA and Seizures

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10 Questions

True or false: A seizure occurs due to an increase in inhibitory activity in the brain?

False

True or false: GABA is the most important excitatory neurotransmitter in the brain?

False

True or false: Benzodiazepines bind to multiple receptor sites on GABA-A receptors?

True

True or false: Lorazepam and diazepam are commonly used for long-term treatment of epilepsy?

False

True or false: Phenobarbital is one of the barbiturates commonly used in the treatment of epilepsy?

True

What is the most important inhibitory neurotransmitter in the brain?

Gamma-aminobutyric acid (GABA)

What are the three substances that have multiple binding sites on GABA-A receptors?

Benzodiazepines, barbiturates, and other substances (eg, picrotoxins, bicuculline, and neurosteroids)

Which benzodiazepines are commonly used for the emergency treatment of seizures?

Lorazepam and diazepam

Why are lorazepam and diazepam not commonly used for long-term treatment of epilepsy?

Because of the development of tolerance

What are the two barbiturates commonly used in the treatment of epilepsy?

Phenobarbital and clobazam

Test your knowledge on the inhibitory neurotransmitter GABA and its role in seizures. Learn about the different substances that bind to GABA-A receptors and affect brain activity.

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