13 Questions
What is one of the main potential advances in the treatment of ED according to the text?
Understanding of the pathophysiology of the disorder
Which medication, currently available in Asia, shows promising safety and efficacy data for treating ED?
Udenafil
What physiological pathway has been shown to improve erectile function in animal models of diabetes according to the text?
RhoA/Rho kinase pathway
What was the future use of apomorphine described as in the text?
Uncertain with mixed results from clinical trials
What does Avanafil show promising results in, based on early Phase I/II trials?
Determining dose tolerability and safety in patients
Which statement best describes the advancements in oral treatment for ED since the introduction of PDE5 inhibitors?
No significant advancements have occurred since the introduction of PDE5 inhibitors over 10 years ago
What is considered the most direct route to improved pharmacotherapeutics for erectile dysfunction?
Development of selective PDE isozyme inhibitors
Why are gene therapy and cell-based treatments not expected to become standard treatments for ED in the near future?
Their limitations and advancements in understanding ED molecular mechanisms
What is a key feature desired in the ideal improvement for treating erectile dysfunction?
Non-invasive with minimal side-effects
Why is there a growing dissatisfaction with the use of current PDE-5 inhibitors to treat ED?
Failure correlated with expectations
Which group of men is less effectively treated by oral PDE-5 inhibitor therapy due to severe affliction?
Men with organic ED who are more severely afflicted
What is the main emphasis when discussing potential advancements in treating neurogenic ED?
Understanding molecular basis and pathophysiology of ED
Why is age-associated ED becoming an increasing area of interest?
'Men remain sexually active into old age'
Explore emerging trends in pharmacotherapeutics for erectile dysfunction (ED) as companies strive to meet the demand of patients. Learn about potential advancements beyond PDE5 inhibitors and the challenges faced in developing new treatments.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
