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Questions and Answers
Which class of antifungal agents primarily inhibits an enzyme necessary to generate ergosterol?
Which class of antifungal agents primarily inhibits an enzyme necessary to generate ergosterol?
- Echinocandins
- Polyenes
- Azoles (correct)
- Allylamines
Which antifungal agent is specifically noted for being effective against dermatophytes and is typically administered orally?
Which antifungal agent is specifically noted for being effective against dermatophytes and is typically administered orally?
- Fluconazole
- Terbinafine (correct)
- Clotrimazole
- Itraconazole
Among the azoles, which agent is the preferred treatment for yeast infections but has limited activity against molds?
Among the azoles, which agent is the preferred treatment for yeast infections but has limited activity against molds?
- Terbinafine
- Fluconazole (correct)
- Clotrimazole
- Itraconazole
Which class of antifungal agents disrupts the fungal cell wall synthesis by inhibiting glucan synthesis?
Which class of antifungal agents disrupts the fungal cell wall synthesis by inhibiting glucan synthesis?
Flucytosine exerts its antifungal effect by inhibiting which process in fungi?
Flucytosine exerts its antifungal effect by inhibiting which process in fungi?
Which antifungal agent penetrates widely into most body tissues, based on the provided information?
Which antifungal agent penetrates widely into most body tissues, based on the provided information?
What is a key reason for the increased incidence of fungal infections according to the text?
What is a key reason for the increased incidence of fungal infections according to the text?
Why are fungal infections generally more difficult to treat compared to bacterial infections?
Why are fungal infections generally more difficult to treat compared to bacterial infections?
Which antifungal agent binds to ergosterol within the fungal cell membrane, leading to pore formation and disruption of the fungal membrane?
Which antifungal agent binds to ergosterol within the fungal cell membrane, leading to pore formation and disruption of the fungal membrane?
What is a common toxic effect associated with the primary polyene antifungal agent, amphotericin B (AMB)?
What is a common toxic effect associated with the primary polyene antifungal agent, amphotericin B (AMB)?
Which class of antifungal agents is known to be toxic for patients while being the only agent that can kill most fungi?
Which class of antifungal agents is known to be toxic for patients while being the only agent that can kill most fungi?
Why is resistance to amphotericin B (AMB) a concern according to the text?
Why is resistance to amphotericin B (AMB) a concern according to the text?
What is a common mechanism of resistance to antifungals mentioned in the text?
What is a common mechanism of resistance to antifungals mentioned in the text?
Which type of infection is flucytosine very effective in treating according to the text?
Which type of infection is flucytosine very effective in treating according to the text?
What is one of the uses of flucytosine as mentioned in the text?
What is one of the uses of flucytosine as mentioned in the text?
In antifungal susceptibility testing, which method involves using different disk diffusion antifungal disks?
In antifungal susceptibility testing, which method involves using different disk diffusion antifungal disks?
What is mentioned as a side effect of the treatment for fungal meningitis in the text?
What is mentioned as a side effect of the treatment for fungal meningitis in the text?
Which pathway alteration is mentioned as a mechanism of resistance to antifungals in the text?
Which pathway alteration is mentioned as a mechanism of resistance to antifungals in the text?
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