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Questions and Answers
What type of change in the pharmacological response is characterized by a change in the duration of the response?
What type of change in the pharmacological response is characterized by a change in the duration of the response?
- Quantitative change
- Qualitative change
- Duration change (correct)
- None of the above
Which factor can lead to prescription errors due to interactions, especially in drugs with a low therapeutic index?
Which factor can lead to prescription errors due to interactions, especially in drugs with a low therapeutic index?
- Self-medication with OTC drugs
- Multiple prescriptions (correct)
- Genetics
- Lack of patient compliance
How can an individual's genetic makeup affect their response to a drug?
How can an individual's genetic makeup affect their response to a drug?
- By affecting pharmacokinetics and pharmacodynamics (correct)
- By changing the pH of the gastrointestinal tract
- By causing therapy failure
- By altering drug binding interactions
Which type of drug interactions are related to co-administration with drugs of abuse?
Which type of drug interactions are related to co-administration with drugs of abuse?
What is a common cause of therapy failure related to drug interactions?
What is a common cause of therapy failure related to drug interactions?
How can mutations impact drug interactions?
How can mutations impact drug interactions?
What is the main sterol in the fungal cell membrane that polyenes bind to?
What is the main sterol in the fungal cell membrane that polyenes bind to?
What characteristic of Fluconazole makes it different from ketoconazole in terms of absorption?
What characteristic of Fluconazole makes it different from ketoconazole in terms of absorption?
Which antifungal agent is used for local infections such as skin and vaginal candidiasis due to its toxicity?
Which antifungal agent is used for local infections such as skin and vaginal candidiasis due to its toxicity?
Which antifungal agent disrupts nucleic acid synthesis by being activated to 5-Flurouracil?
Which antifungal agent disrupts nucleic acid synthesis by being activated to 5-Flurouracil?
What is the mechanism of action of azoles in inhibiting fungal growth?
What is the mechanism of action of azoles in inhibiting fungal growth?
How does Griseofulvin exert its antifungal effect?
How does Griseofulvin exert its antifungal effect?
Which antifungal agent is a CYP450 inducer, potentially causing therapy failure of other drugs?
Which antifungal agent is a CYP450 inducer, potentially causing therapy failure of other drugs?
Which antifungal agent is used intrathecally to reach cerebrospinal fluid for meningitis treatment?
Which antifungal agent is used intrathecally to reach cerebrospinal fluid for meningitis treatment?
What formulation of Amphotericin-B is used to reduce nephrotoxicity by increasing tolerance?
What formulation of Amphotericin-B is used to reduce nephrotoxicity by increasing tolerance?
What is the main indication for the use of Flucytosine in combination therapy?
What is the main indication for the use of Flucytosine in combination therapy?
Which antifungal agent inhibits ergosterol synthesis at the level of squalene epoxidase?
Which antifungal agent inhibits ergosterol synthesis at the level of squalene epoxidase?
Which fungal infection causes wart-like lesions on the skin and subcutaneous tissue?
Which fungal infection causes wart-like lesions on the skin and subcutaneous tissue?
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