Fungal Infections: Dermatophytosis and Deep Fungal Infections
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Questions and Answers

What is the major test used when dermatophytosis is suspected?

  • Culture in Luria-Bertani agar
  • Culture in Sabouraud’s glucose agar (correct)
  • Urine test for fungal presence
  • Blood test for glucose levels
  • Which treatment is recommended for tinea superficialis in hairy areas?

  • Systemic penicillin
  • Topical application of antifungal agents such as imidazole
  • Intramuscular corticosteroids
  • Systemic itraconazole (correct)
  • What is no longer commonly used in Japan for treating dermatophytosis?

  • Terbinafine hydrochloride
  • Itraconazole
  • Miconazole
  • Griseofulvin (correct)
  • Which test involves morphological observation of conidium by slide culture?

    <p>Slide culture</p> Signup and view all the answers

    For which type of tinea infection are systemic itraconazole and terbinafine hydrochloride recommended?

    <p>Tinea profunda with cutaneous symptoms</p> Signup and view all the answers

    What is a characteristic of fungi?

    <p>They have a cellular wall</p> Signup and view all the answers

    Where do dermatophytes commonly infect in the human body?

    <p>Epidermal horny cell layer, nails, and hair follicles</p> Signup and view all the answers

    What type of fungal infection involves parasitization of the dermis and deeper layers?

    <p>Tinea profunda</p> Signup and view all the answers

    How is the diagnosis of dermatophytosis confirmed?

    <p>Locating segmental spores containing septum in a specimen with KOH solution</p> Signup and view all the answers

    What makes rapid microscopic examination of dermatophytes possible?

    <p>Using DMSO-added KOH solution</p> Signup and view all the answers

    Which of the following is NOT true about dermatophytes?

    <p>They proliferate mainly in the nervous system</p> Signup and view all the answers

    Study Notes

    Diagnostic Tests and Treatment for Dermatophytosis

    • KOH Preparation: Major test used when dermatophytosis is suspected, allowing for the visualization of fungal elements.
    • Tinea Superficialis Treatment: Recommended treatment for tinea superficialis in hairy areas includes topical antifungals like clotrimazole or miconazole.
    • Outdated Treatment in Japan: Griseofulvin is no longer commonly used for treating dermatophytosis in Japan.

    Fungal Infections Overview

    • Slide Culture Test: Test involving morphological observation of conidia to identify dermatophytes via a slide culture method.
    • Recommended Systemic Treatments: Systemic itraconazole and terbinafine hydrochloride are recommended for treating tinea corporis and other widespread dermatophyte infections.

    General Characteristics of Dermatophytes

    • Fungal Characteristics: Fungi are characterized by their ability to be saprophytic or parasitic, commonly forming filamentous structures (hyphae).
    • Common Infection Sites: Dermatophytes typically infect keratin-rich areas such as skin, hair, and nails due to their affinity for keratin.

    Pathogenesis and Diagnosis

    • Fungal Infection Depth: Dermatophytes can cause infection involving parasitization of the dermis and deeper layers, such as in cases of tinea corporis or tinea capitis.
    • Diagnosis Confirmation: Diagnosis of dermatophytosis is confirmed via culture and identification of the causal organism or through KOH preparation showing hyphae and spores.

    Microscopic Examination and Misconceptions

    • Rapid Microscopic Examination: Possible due to the unique morphological features of dermatophytes which can be observed after KOH treatment.
    • Misconception About Dermatophytes: Not all dermatophytes are capable of causing infections in every individual; susceptibility varies based on immune response and environmental conditions.

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    Description

    Explore the characteristics of fungal infections, including dermatophytosis and deep fungal infections. Learn about the parasitic nature of fungi in different tissue layers and their classification into genera. Understand the impact of dermatophytes on the skin and nails.

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