Fungal Characteristics and Classification
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Questions and Answers

What feature distinguishes fungi from plants?

  • Ability to perform photosynthesis
  • Cell wall composed of cellulose
  • Presence of chlorophyll
  • Heterotrophic nature (correct)
  • Which statement accurately describes the cell structure of fungi compared to bacteria?

  • Fungi lack sterols in their membranes
  • Fungi have peptidoglycans in their cell walls
  • Fungi are prokaryotic organisms
  • Fungi are eukaryotic organisms (correct)
  • Which type of fungi is characterized as multicellular and reproduces by forming airborne spores?

  • Lichens
  • Mold (correct)
  • Yeast
  • Mycorrhizae
  • What is a significant difference between septate and non-septate hyphae?

    <p>Non-septate hyphae lack walls between cells (D)</p> Signup and view all the answers

    Which of the following defines saprotrophic fungi?

    <p>Fungi that decompose dead organic matter (B)</p> Signup and view all the answers

    In what form can fungi exist when located within animal tissue?

    <p>Yeast (D)</p> Signup and view all the answers

    What distinguishes mycorrhizae from lichens?

    <p>Mycorrhizae consist of fungi and plants, while lichens consist of fungi and algae (C)</p> Signup and view all the answers

    How do fungi primarily reproduce asexually?

    <p>Budding and spore formation (B)</p> Signup and view all the answers

    Which of the following conditions does not influence the classification of fungi?

    <p>Hydration levels (B)</p> Signup and view all the answers

    What makes fungi facultative anaerobes distinct from obligate anaerobes?

    <p>They can switch between aerobic and anaerobic respiration. (A)</p> Signup and view all the answers

    What differentiates a secondary cell culture from a primary cell culture?

    <p>Secondary cell cultures are created by transferring cells into fresh growth medium. (D)</p> Signup and view all the answers

    Which prion protein is known to be abnormal and associated with disease?

    <p>PrPsc (D)</p> Signup and view all the answers

    What is the primary characteristic of a communicable disease?

    <p>It is readily spread from person to person. (C)</p> Signup and view all the answers

    What type of cell culture is characterized by being not affected by contact inhibition?

    <p>Continuous cell line (A)</p> Signup and view all the answers

    Which antiviral drug works specifically by inhibiting genome replication?

    <p>Acyclovir (B)</p> Signup and view all the answers

    Which of the following best defines the term 'syndrome'?

    <p>A collection of signs and symptoms characteristic of a disease. (A)</p> Signup and view all the answers

    What role do host cells play in the cultivation of animal viruses?

    <p>They are essential for the replication of the viruses. (A)</p> Signup and view all the answers

    What is the significance of plaques in the study of bacteriophages?

    <p>They represent clear zones formed by bacteriophage activity. (A)</p> Signup and view all the answers

    What is a primary characteristic of iatrogenic diseases?

    <p>They are contracted as a result of medical procedures. (A)</p> Signup and view all the answers

    What defines the prodromal phase of a disease?

    <p>It is when the pathogen starts to multiply in the host. (D)</p> Signup and view all the answers

    What is a defining characteristic of Basidiomycota among fungal phyla?

    <p>They produce visible fruiting bodies, like mushrooms. (B)</p> Signup and view all the answers

    Which of the following fungal species is associated with Candidiasis?

    <p>Candida albicans (B)</p> Signup and view all the answers

    What type of reproduction do Zygomycota utilize for producing diploid zygotes?

    <p>Sexual reproduction through zygospores. (D)</p> Signup and view all the answers

    Which phylum does not possess septa in its hyphae?

    <p>Glomeromycota (C), Zygomycota (D)</p> Signup and view all the answers

    What is the primary cause of Histoplasmosis?

    <p>Histoplasma capsulatum (B)</p> Signup and view all the answers

    What is the primary function of the polar tubule found in Microsporidia?

    <p>To penetrate host cell membranes for fungal entry. (A)</p> Signup and view all the answers

    What type of RNA serves as a template for synthesizing +ssRNA in viral replication?

    <p>-ssRNA (B)</p> Signup and view all the answers

    What common condition is caused by the fungus Trichophyton?

    <p>Dermatophytosis (Ringworm) (C)</p> Signup and view all the answers

    During which stage of bacteriophage replication does the viral DNA enter the host?

    <p>Penetration (C)</p> Signup and view all the answers

    What distinguishes virulence from pathogenicity?

    <p>Pathogenicity is the ability to cause disease, while virulence is the degree of this ability. (C)</p> Signup and view all the answers

    Which of the following correctly describes the behavior of opportunistic pathogens?

    <p>They only infect hosts with a compromised immune system. (A)</p> Signup and view all the answers

    Which stage of pathogenesis involves the pathogen evading the host immune response?

    <p>Invasion (C)</p> Signup and view all the answers

    What is a primary characteristic of systemic infections?

    <p>They spread throughout the body and affect deeper organs. (C)</p> Signup and view all the answers

    Which of these virulence factors is specifically related to enhancing pathogen penetration during invasion?

    <p>Collagenase (C)</p> Signup and view all the answers

    How do exotoxins differ from endotoxins?

    <p>Exotoxins are released into the environment, whereas endotoxins are released upon cell disintegration. (D)</p> Signup and view all the answers

    Which process allows a pathogen to remain alive and divide within a host's phagosome?

    <p>Intracellular survival mechanisms (D)</p> Signup and view all the answers

    What role does hyaluronidase play in pathogen invasion?

    <p>It facilitates penetration through tissues. (A)</p> Signup and view all the answers

    Which of these situations exemplifies a secondary infection?

    <p>A patient with HIV develops thrush. (B)</p> Signup and view all the answers

    Flashcards

    Fungi vs. Plants

    Fungi lack chlorophyll and cannot photosynthesize (heterotrophic), while plants use chlorophyll for photosynthesis (autotrophic).

    Fungi vs. Bacteria

    Fungi are eukaryotic (have a nucleus), while bacteria are prokaryotic (no nucleus); fungi have sterols in their cell membranes, while bacteria do not; fungi cell walls lack peptidoglycans, which are present in bacteria.

    Fungal Forms

    Fungi exist as either molds (multicellular, aerobic) or yeasts (unicellular, facultative anaerobes).

    Fungal Reproduction (Asexual)

    Fungi reproduce asexually through budding (cell division to form a new cell) or transverse division (cell divides down the middle).

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    Hyphae

    Filaments that absorb nutrients from the environment. They extend lengthwise, creating new filaments.

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    Mycelium

    The collection of hyphae, which can form a visible mass or network.

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    Fungal Nutrition (Saprotroph)

    Fungi that decompose dead organic matter, recycling nutrients.

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    Mycorrhizae

    Symbiotic relationship between fungi and plant roots, where both benefit. Fungus gets carbon, the plant gets minerals and water.

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    Fungal Classification (Dimorphism)

    Fungi can change forms depending on the conditions (temperature, location).

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    Fungal Classification (Location)

    Fungi change from yeast to hyphae (and back) depending on factors like temperature and location within or outside a host.

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    Asexual reproduction in fungi

    A type of fungal reproduction where offspring are genetically identical to the parent. This is done through spores germinating, resulting in daughter organism similar to parent.

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    Sexual reproduction in fungi

    Fusion of nuclei from two different strains of the same fungal species, resulting in a genetically different offspring

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    Glomeromycota

    A phylum of fungi that form symbiotic relationships with plant roots, forming endomycorrhizae. They're essential for plant nutrition as they live inside the roots of about 80% of plants.

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    Chytridiomycota

    The oldest and simplest fungal phylum, mostly aquatic. The chytrids are a diverse group of fungi.

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    Zygomycota

    A phylum of fungi including saprophytic and parasitic species. Noteworthy for sexual reproduction via zygospores (diploid zygotes).

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    Ascomycota

    A large phylum of fungi, including many important species in food and medicine. Distinguished by septated hyphae, asexual reproduction via conidiospores, and sexual reproduction via ascospores.

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    Basidiomycota

    A phylum of fungi known for their visible fruiting bodies. includes saprotrophic species and mushrooms

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    Microsporidia

    A phylum of obligate intracellular parasitic fungi. Characterized by polar tubules for host cell infection which are key structures of these pathogens.

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    Infectious Disease

    Histoplasmosis- caused by Histoplasma capsulatum; often acquired by inhaling spores in soil or animal environments

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    Fungal Disease

    Dermatophytosis-Fungal infection of hair, skin, and nails. Characterized by ring-like lesions.

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    Pathogenicity

    The ability of a microbe to cause disease.

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    Virulence

    The degree or severity of a pathogen's ability to cause disease.

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    Primary Pathogen

    A microbe that can cause disease in a healthy host, regardless of their existing microbiota.

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    Opportunistic Pathogen

    A microbe that only causes disease when the host's immune system is compromised.

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    Exposure

    The initial stage of infection where the pathogen enters the host.

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    Adhesion

    The process of the pathogen attaching to the host's cells.

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    Invasion

    The pathogen's ability to evade the host's immune system and spread within the body.

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    Infection

    The pathogen multiplying and causing damage to the host.

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    Exit

    The final stage of infection where the pathogen leaves the host to infect others.

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    Local Infection

    An infection confined to a specific area, usually near the point of entry.

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    Fertilized Chicken Egg

    A chicken egg that has been fertilized by a rooster, containing various structures essential for embryonic development.

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    Chorioallantoic Membrane

    A membrane in a fertilized chicken egg, responsible for gas exchange and waste removal.

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    Amniotic Cavity

    The fluid-filled sac within a fertilized chicken egg, where the developing chick is suspended.

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    Yolk Sac

    The structure in a fertilized chicken egg that provides nourishment to the developing chick.

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    Primary Cell Culture

    Cells directly isolated from animal tissues and grown in a solution.

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    Contact Inhibition

    The phenomenon where cells stop dividing when they come into contact with each other.

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    Continuous Cell Line

    Cells that can be grown indefinitely in culture, often derived from cancerous cells.

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    Cytopathic Effects

    Visible changes in host cells caused by viral infection, detectable under a microscope.

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    Syncytia

    Giant multinucleated cells formed by the fusion of infected host cells.

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    Prions

    Infectious proteins that can cause disease by misfolding and accumulating in the brain.

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    Study Notes

    Fungal Characteristics and Classification

    • Fungi lack chlorophyll and cannot perform photosynthesis, making them heterotrophic.
    • Their cell walls are composed of chitin.
    • Fungi are eukaryotic, distinguishing them from prokaryotic bacteria.
    • Fungal membranes contain sterols, absent in bacterial membranes.
    • Fungi's cell walls lack peptidoglycans, a component found in bacterial walls.

    Fungal Forms and Structure

    • Fungi exist in two forms: mold and yeast.
    • Mold is multicellular, aerobic, and reproduces by forming spores.
    • Yeast is unicellular, and is a facultative anaerobe. It reproduces both sexually and asexually (budding, transverse division).
    • Hyphae are filaments that absorb nutrients, and mycelia are a collection of hyphae.
    • Septate hyphae have walls (septa) between cells; non-septate hyphae do not.

    Fungal Nutrition

    • Fungi can obtain carbon in three ways:
      • Saprotrophs decompose dead organic matter.
      • Parasites feed on living hosts.
      • Symbionts live with other organisms like algae.
    • Mycorrhizae are symbiotic associations between fungi and plant roots.
    • Lichens are symbiotic associations of fungi and algae.

    Fungal Reproduction

    • Fungi reproduce asexually through spore formation from hyphae, resulting in identical offspring. This is a faster process.
    • Sexual reproduction involves the fusion of nuclei from two mating strains, producing genetic variation. This is less common than asexual reproduction.

    Fungal Phyla

    • Chytridiomycota: Non-septate, oldest, simplest, aquatic fungi, one class- chytrids.
    • Glomeromycota: Non-septate, obligate symbionts forming endomycorrhizae (live in roots of 80% of plants).
    • Zygomycota: Non-septate, saprotrophic/parasitic, key members in food science and crop pathogens; reproduce sexually by zygospores and asexually by sporangiospores.
    • Ascomycota: Septate, largest phylum (75%), involved in food production, disease, and symbiotic relationships; reproduce asexually by conidiospores and sexually by ascospores.
    • Basidiomycota: Septate, characterized by visible fruiting bodies (e.g., mushrooms); involved in symbiotic, saprotrophic, and parasitic relationships; reproduce asexually by conidiospores and sexually by basidiospores.
    • Microsporidia: Non-septate, obligate intracellular parasites; use a polar tubule for host cell entry.

    Fungal Diseases

    • Ergotism: Middle Ages European disease, used to induce abortions.
    • Histoplasmosis: "Summer flu", lower respiratory infection caused by Histoplasma capsulatum (inhalation of spores in soil, chicken coops, bat caves).
    • Dermatophytosis (Ringworm): Fungal disease of hair, skin, and nails; caused by Trichophyton (nails) and Microsporum (skin/scalp).
    • Candidiasis (Thrush and Yeast Infection): Caused by Candida albicans; includes vulvovaginitis (yeast infection) and thrush (oral infection).
    • Coccidioidomycosis: "Valley fever", caused by Coccidioides immitis and C. posadasii (inhalation of dust particles with fungal spores).

    Acellular Pathogens (Viruses)

    • Viruses are non-living, infectious agents composed of nucleic acid (DNA or RNA) surrounded by a protein capsid.
    • Capsid forms can be helical, icosahedral, or complex.
    • Host range refers to the organisms a virus can infect, with tissue specificity within those organisms.

    Bacteriophage Replication

    • Attachment, penetration, biosynthesis, maturation, and lysis are the steps of bacteriophage replication.
    • Bacteriophages utilize the host's machinery for biosynthesis.
    • Virulent phages undergo the lytic cycle; temperate phages enter the lysogenic cycle, becoming part of the host's chromosome.
    • Stress can cause a temperate phage to switch to the lytic cycle.

    Animal Virus Replication

    • Animal virus replication differs from bacteriophage replication.
    • Uncoating releases viral nucleic acid from the capsid into the host cell cytoplasm.
    • Enveloped viruses penetrate by fusion with the host's plasma membrane, while non-enveloped viruses enter via endocytosis.
    • +ssRNA viruses directly use ribosomes for protein synthesis; -ssRNA viruses use their RNA as a template for +ssRNA synthesis.
    • Enveloped viruses release by fusing with plasma membrane; some do "budding."

    Retroviruses

    • Retroviruses are RNA viruses that use reverse transcriptase to produce DNA from their RNA.

    Viral Growth Curve

    • Inoculation, eclipse, burst are steps of viral growth curve
    • Burst size is maximum number of virions produced per bacterium.

    Cultivation of Viruses

    • Animal viruses are cultivated in fertilized chicken eggs (various sites) and/or cell cultures.
    • Cell cultures can be primary (limited life span, contact inhibition), secondary (from primary), or continuous cell lines (derived from tumors, indefinite life span, no contact inhibition).
    • Bacteriophages are cultivated on a bacterial lawn, forming plaques.

    Detecting Viruses

    • Scientists detect viruses by cytopathic effects, such as syncytia formation or cell inclusions.

    Viroids and Virusoids

    • Viroids are non-infectious single-stranded RNA that cause plant diseases requiring a host for replication; they don't encode proteins.
    • Virusoids are infectious single-stranded RNA that require a helper virus to replicate.

    Prions

    • Prions are infectious self-replicating proteins causing diseases.
    • Two types are PrPc (normal) and PrPsc (abnormal, misfolded, disease-causing).

    Prion Disease Transmission

    • PrPSC converts normal PrPc to PrPSC causing the accumulation.

    Antiviral Drugs

    • Antiviral drugs target various stages of viral replication.

    Microbial Mechanisms of Pathogenicity

    • Infection is the multiplication of a microbe in a host.
    • Disease is an altered state of health.
    • Signs are measurable indicators of disease (e.g., vital signs); symptoms are changes in body function (e.g., pain, nausea); syndromes are collections of signs/symptoms.
    • Infectious diseases are caused by pathogens; non-infectious diseases are not.
    • Communicable diseases spread between people.
    • Iatrogenic diseases are contracted from medical procedures.
    • Nosocomial diseases are acquired in hospitals.
    • Zoonotic diseases are transmitted from animals to humans.

    Disease Periods

    • Incubation, prodromal, acute, decline, and convalescence.

    Disease Types

    • Acute diseases develop, peak, and resolve quickly.
    • Chronic diseases progress slowly and persist for an extended period.

    Pathogenicity and Virulence

    • Pathogenicity is a microbe's ability to cause disease.
    • Virulence is the degree of pathogenicity.

    Primary vs. Opportunistic Pathogens

    • Primary pathogens cause disease in healthy hosts; opportunistic pathogens cause disease in compromised hosts.

    Stages of Pathogenesis

    • Exposure, adhesion, invasion, infection, and exit.

    Portals of Entry/Exit

    • Portals range from eyes, nose, mouth, broken skin and insect bites, anus or urethra.

    Microbial Invasion Mechanisms

    • Mechanisms to invade include biofilm formation, enzymes (like coagulase, streptokinase, hyaluronidase, collagenase), and toxins.

    Infection Classifications

    • Local, focal, and systemic.

    Primary vs. Secondary Infections

    • Primary infections occur in healthy individuals; secondary infections occur in individuals weakened by a primary infection.

    Antigenic Variation

    • Pathogens alter surface proteins to evade host defenses by Antigenic variation by mutating spike proteins.

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    Description

    This quiz covers essential characteristics and classifications of fungi, discussing their unique traits such as eukaryotic structure, forms, and nutritional methods. It delves into the differences between molds and yeasts, their structural components, and reproductive processes. Test your knowledge on the fascinating world of fungi!

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