Podcast
Questions and Answers
What is the main function of cartilage in the trachea?
What is the main function of cartilage in the trachea?
Which type of cartilage is found in the growth plates of bones?
Which type of cartilage is found in the growth plates of bones?
What percentage of water makes up the matrix of cartilage?
What percentage of water makes up the matrix of cartilage?
What component is most abundant in the matrix of cartilage?
What component is most abundant in the matrix of cartilage?
Signup and view all the answers
Which type of cartilage is described as a mixture of cartilage and dense regular connective tissue?
Which type of cartilage is described as a mixture of cartilage and dense regular connective tissue?
Signup and view all the answers
What is the function of cartilage in joint surfaces?
What is the function of cartilage in joint surfaces?
Signup and view all the answers
What is the role of chondrocytes in cartilage?
What is the role of chondrocytes in cartilage?
Signup and view all the answers
Which component is absent in the matrix of cartilage?
Which component is absent in the matrix of cartilage?
Signup and view all the answers
In which structure would you find elastic cartilage?
In which structure would you find elastic cartilage?
Signup and view all the answers
What is the primary function of perichondrium in cartilage?
What is the primary function of perichondrium in cartilage?
Signup and view all the answers
What is a key feature that makes cartilage firm yet resilient?
What is a key feature that makes cartilage firm yet resilient?
Signup and view all the answers
What type of tissue makes up the inner chondrogenic layer of perichondrium?
What type of tissue makes up the inner chondrogenic layer of perichondrium?
Signup and view all the answers
Which type of collagen is most abundant in the glassy/slippery matrix of Hyaline Cartilage?
Which type of collagen is most abundant in the glassy/slippery matrix of Hyaline Cartilage?
Signup and view all the answers
What type of cartilage is found essentially all over the ribcage in a 9-week fetus?
What type of cartilage is found essentially all over the ribcage in a 9-week fetus?
Signup and view all the answers
What type of matrix does Elastic Cartilage predominantly contain?
What type of matrix does Elastic Cartilage predominantly contain?
Signup and view all the answers
Where are sulfated Glycosaminoglycans (GAG’s) mainly found in the cartilage matrix?
Where are sulfated Glycosaminoglycans (GAG’s) mainly found in the cartilage matrix?
Signup and view all the answers
What provides the resilience and lubricating abilities in the cartilage matrix?
What provides the resilience and lubricating abilities in the cartilage matrix?
Signup and view all the answers
In which type of cartilage are collagen type I fibers arranged parallel to the line of pull/stress?
In which type of cartilage are collagen type I fibers arranged parallel to the line of pull/stress?
Signup and view all the answers
What type of GAG's have anionic groups rendering them intensely hydrophilic?
What type of GAG's have anionic groups rendering them intensely hydrophilic?
Signup and view all the answers
What is the primary function of proteoglycans in the cartilage matrix?
What is the primary function of proteoglycans in the cartilage matrix?
Signup and view all the answers
What characterizes the location and arrangement of chondrocytes in hyaline cartilage?
What characterizes the location and arrangement of chondrocytes in hyaline cartilage?
Signup and view all the answers
What type of fibers are most prominent in fibrocartilage, providing it with tensile strength?
What type of fibers are most prominent in fibrocartilage, providing it with tensile strength?
Signup and view all the answers
What is the primary difference between elastic cartilage and articular cartilage?
What is the primary difference between elastic cartilage and articular cartilage?
Signup and view all the answers
What is a key characteristic that distinguishes hyaline cartilage from fibrocartilage?
What is a key characteristic that distinguishes hyaline cartilage from fibrocartilage?
Signup and view all the answers
What is the primary difference between osteoarthritis and classic inflammatory conditions?
What is the primary difference between osteoarthritis and classic inflammatory conditions?
Signup and view all the answers
Which of the following is NOT listed as a risk factor for osteoarthritis?
Which of the following is NOT listed as a risk factor for osteoarthritis?
Signup and view all the answers
What is one of the key pathologic features observed in early osteoarthritis?
What is one of the key pathologic features observed in early osteoarthritis?
Signup and view all the answers
What is the primary difference between primary and secondary osteoarthritis?
What is the primary difference between primary and secondary osteoarthritis?
Signup and view all the answers
Which of the following is listed as a risk factor for the development of osteoarthritis?
Which of the following is listed as a risk factor for the development of osteoarthritis?
Signup and view all the answers
What type of changes are observed in the extracellular matrix (ECM) in osteoarthritis?
What type of changes are observed in the extracellular matrix (ECM) in osteoarthritis?
Signup and view all the answers
Which of the following is NOT a pathway involved in the pathogenesis of osteoarthritis?
Which of the following is NOT a pathway involved in the pathogenesis of osteoarthritis?
Signup and view all the answers
Which phase of osteoarthritis involves genetic and environmental factors leading to chondrocyte injury?
Which phase of osteoarthritis involves genetic and environmental factors leading to chondrocyte injury?
Signup and view all the answers
What are some of the primary risk factors associated with developing osteoarthritis?
What are some of the primary risk factors associated with developing osteoarthritis?
Signup and view all the answers
What are some common symptoms of patients with osteoarthritis?
What are some common symptoms of patients with osteoarthritis?
Signup and view all the answers
What is one of the main structural tissues affected by osteoarthritis?
What is one of the main structural tissues affected by osteoarthritis?
Signup and view all the answers
What are some common treatments for patients with osteoarthritis?
What are some common treatments for patients with osteoarthritis?
Signup and view all the answers
What is the primary function of cartilage in the intervertebral disk?
What is the primary function of cartilage in the intervertebral disk?
Signup and view all the answers
Which component is most abundant in the matrix of hyaline cartilage?
Which component is most abundant in the matrix of hyaline cartilage?
Signup and view all the answers
What distinguishes elastic cartilage as the rarest among the three types of cartilage?
What distinguishes elastic cartilage as the rarest among the three types of cartilage?
Signup and view all the answers
What is the primary function of the perichondrium in cartilage?
What is the primary function of the perichondrium in cartilage?
Signup and view all the answers
In which type of cartilage would you find a mixture of cartilage and dense regular connective tissue?
In which type of cartilage would you find a mixture of cartilage and dense regular connective tissue?
Signup and view all the answers
What characterizes the matrix of elastic cartilage that contributes to its unique properties?
What characterizes the matrix of elastic cartilage that contributes to its unique properties?
Signup and view all the answers
Which factor primarily accounts for the resilience and lubricating abilities of the cartilage matrix?
Which factor primarily accounts for the resilience and lubricating abilities of the cartilage matrix?
Signup and view all the answers
What distinguishes fibrocartilage from elastic and hyaline cartilage?
What distinguishes fibrocartilage from elastic and hyaline cartilage?
Signup and view all the answers
What key component is mainly responsible for establishing the unique properties of cartilage?
What key component is mainly responsible for establishing the unique properties of cartilage?
Signup and view all the answers
What is a significant characteristic of chondrocytes in cartilage?
What is a significant characteristic of chondrocytes in cartilage?
Signup and view all the answers
What primarily distinguishes hyaline cartilage from fibrocartilage?
What primarily distinguishes hyaline cartilage from fibrocartilage?
Signup and view all the answers
What plays a crucial role in cartilage's reliance on diffusion for nutrient supply?
What plays a crucial role in cartilage's reliance on diffusion for nutrient supply?
Signup and view all the answers
Which type of cartilage exhibits a 'highly plastic' nature, being firm yet resilient?
Which type of cartilage exhibits a 'highly plastic' nature, being firm yet resilient?
Signup and view all the answers
Which type of cartilage is most widespread in the body?
Which type of cartilage is most widespread in the body?
Signup and view all the answers
What characterizes the matrix of Elastic Cartilage?
What characterizes the matrix of Elastic Cartilage?
Signup and view all the answers
Which component is primarily responsible for the resilience and lubricating abilities in the cartilage matrix?
Which component is primarily responsible for the resilience and lubricating abilities in the cartilage matrix?
Signup and view all the answers
Where are sulfated Glycosaminoglycans (GAG’s) mainly located within the cartilage matrix?
Where are sulfated Glycosaminoglycans (GAG’s) mainly located within the cartilage matrix?
Signup and view all the answers
What distinguishes fibrocartilage from other types of cartilage?
What distinguishes fibrocartilage from other types of cartilage?
Signup and view all the answers
What is the primary function of the perichondrium in relation to the cartilage?
What is the primary function of the perichondrium in relation to the cartilage?
Signup and view all the answers
Which unique feature characterizes elastic cartilage found in specific body structures like the ear?
Which unique feature characterizes elastic cartilage found in specific body structures like the ear?
Signup and view all the answers
'Territorial Basophilic' staining in the interterritorial matrix of articular cartilage is primarily due to what component?
'Territorial Basophilic' staining in the interterritorial matrix of articular cartilage is primarily due to what component?
Signup and view all the answers
Which type of GAG's have anionic groups that make them intensely hydrophilic?
Which type of GAG's have anionic groups that make them intensely hydrophilic?
Signup and view all the answers
Where would you find isogenous groups within cartilage tissue?
Where would you find isogenous groups within cartilage tissue?
Signup and view all the answers
What tissue serves as a provisional skeleton during embryonic/fetal development?
What tissue serves as a provisional skeleton during embryonic/fetal development?
Signup and view all the answers
What is the primary characteristic that makes Hyaline Cartilage different from Elastic Cartilage?
What is the primary characteristic that makes Hyaline Cartilage different from Elastic Cartilage?
Signup and view all the answers
What is the primary difference between primary and secondary osteoarthritis?
What is the primary difference between primary and secondary osteoarthritis?
Signup and view all the answers
Which of the following risk factors is NOT associated with the development of osteoarthritis?
Which of the following risk factors is NOT associated with the development of osteoarthritis?
Signup and view all the answers
What is the role of proinflammatory mediators in the pathogenesis of osteoarthritis?
What is the role of proinflammatory mediators in the pathogenesis of osteoarthritis?
Signup and view all the answers
Which phase of osteoarthritis involves the loss of chondrocytes and cartilage, along with subchondral changes?
Which phase of osteoarthritis involves the loss of chondrocytes and cartilage, along with subchondral changes?
Signup and view all the answers
What characterizes the early pathologic features of osteoarthritis?
What characterizes the early pathologic features of osteoarthritis?
Signup and view all the answers
In osteoarthritis, what contributes to the disordered repair of cartilage?
In osteoarthritis, what contributes to the disordered repair of cartilage?
Signup and view all the answers
What is one of the key roles of proteases in the pathology of osteoarthritis?
What is one of the key roles of proteases in the pathology of osteoarthritis?
Signup and view all the answers
What leads to composition changes in proteoglycans in osteoarthritis?
What leads to composition changes in proteoglycans in osteoarthritis?
Signup and view all the answers
Which growth factors are involved in other pathways contributing to osteoarthritis?
Which growth factors are involved in other pathways contributing to osteoarthritis?
Signup and view all the answers
What is one of the primary structural tissues affected by osteoarthritis?
What is one of the primary structural tissues affected by osteoarthritis?
Signup and view all the answers
Which phase involves chondrocytes proliferating and releasing inflammatory mediators in osteoarthritis?
Which phase involves chondrocytes proliferating and releasing inflammatory mediators in osteoarthritis?
Signup and view all the answers
What is one of the primary risk factors for developing osteoarthritis?
What is one of the primary risk factors for developing osteoarthritis?
Signup and view all the answers
