Podcast
Questions and Answers
Which drug inhibits dihydrofolate reductase and decreases synthesis of dTMP, RNA, and protein?
Which drug inhibits dihydrofolate reductase and decreases synthesis of dTMP, RNA, and protein?
- Methotrexate (correct)
- 6-Mercaptopurine
- Azathioprine
- 5-Fluorouracil
Which drug induces mutations by pairing with both cytosine and thymine, and inhibits de novo purine synthesis?
Which drug induces mutations by pairing with both cytosine and thymine, and inhibits de novo purine synthesis?
- Azathioprine
- 6-Thioguanine (correct)
- 5-Fluorouracil
- Methotrexate
Which drug binds thymidylate synthase and decreases dTMP, and is used for solid tumors like lung, breast, and ovary?
Which drug binds thymidylate synthase and decreases dTMP, and is used for solid tumors like lung, breast, and ovary?
- Azathioprine
- 5-Fluorouracil (correct)
- 6-Mercaptopurine
- Methotrexate
Which drug is a pyrimidine analog that specifically inhibits thymidylate synthase?
Which drug is a pyrimidine analog that specifically inhibits thymidylate synthase?
Which drug is a monoclonal antibody that prevents EGF binding to the receptor?
Which drug is a monoclonal antibody that prevents EGF binding to the receptor?
Which drug is a monoclonal antibody against VEGF and acts as an angiogenesis inhibitor?
Which drug is a monoclonal antibody against VEGF and acts as an angiogenesis inhibitor?
Which drug is a monoclonal antibody that blocks CTLA-4?
Which drug is a monoclonal antibody that blocks CTLA-4?
Which drug is a monoclonal antibody that blocks PD-1?
Which drug is a monoclonal antibody that blocks PD-1?
Which drug is used for metastatic renal cell carcinoma and metastatic malignant melanoma?
Which drug is used for metastatic renal cell carcinoma and metastatic malignant melanoma?
Which drug is a B-RAF inhibitor used for late-stage melanoma?
Which drug is a B-RAF inhibitor used for late-stage melanoma?
Which drug is an epigenetic target used for myelodysplastic syndrome ('preleukemia')?
Which drug is an epigenetic target used for myelodysplastic syndrome ('preleukemia')?
Which drug is an immunotherapy used for metastatic colorectal cancer and lung cancer - NSCLC?
Which drug is an immunotherapy used for metastatic colorectal cancer and lung cancer - NSCLC?
Which drug inhibits topoisomerase II and thereby induces double-strand DNA breaks?
Which drug inhibits topoisomerase II and thereby induces double-strand DNA breaks?
Which drug stabilizes microtubules of the mitotic spindle?
Which drug stabilizes microtubules of the mitotic spindle?
Which drug is known for its addition of alkyl group and cross-linking DNA at Guanine residues?
Which drug is known for its addition of alkyl group and cross-linking DNA at Guanine residues?
Which drug is used to treat metastatic ovarian cancer and colorectal cancer?
Which drug is used to treat metastatic ovarian cancer and colorectal cancer?
Which drug is an estrogen receptor antagonist in breast but also a partial agonist in some other organs?
Which drug is an estrogen receptor antagonist in breast but also a partial agonist in some other organs?
Which drug prevents conversion of testosterone to estradiol and is used in advanced breast cancer?
Which drug prevents conversion of testosterone to estradiol and is used in advanced breast cancer?
Which drug is a kinase inhibitor that inhibits HER2 and EGFR?
Which drug is a kinase inhibitor that inhibits HER2 and EGFR?
Which drug is an agonist of retinoic acid receptor and is used in the treatment of Acute Promyelocytic Leukemia?
Which drug is an agonist of retinoic acid receptor and is used in the treatment of Acute Promyelocytic Leukemia?
Which drug inhibits CYP17A1 and androgen synthesis, and is used in castration-resistant prostate cancer?
Which drug inhibits CYP17A1 and androgen synthesis, and is used in castration-resistant prostate cancer?
Which drug is known for its fluid retention and is used in the treatment of HER2-positive breast cancer?
Which drug is known for its fluid retention and is used in the treatment of HER2-positive breast cancer?
Which drug intercalates into DNA and inhibits DNA replication and transcription?
Which drug intercalates into DNA and inhibits DNA replication and transcription?
Which drug is a topoisomerase I inhibitor and leads to single-strand DNA breaks?
Which drug is a topoisomerase I inhibitor and leads to single-strand DNA breaks?
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