Folding

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Questions and Answers

Which direction does the winding of the triple helix occur?

  • In a random direction
  • From the amino terminus towards the carboxyl
  • From the carboxyl towards the amino terminus (correct)
  • In both directions simultaneously

What initiates the winding of the triple helix?

  • Interaction of amino-terminal globular domains
  • Formation of procollagen
  • Formation of disulfide bonds
  • Interaction of carboxy-terminal globular domains (correct)

What happens when carboxy-terminal globular domains fold?

  • Disulfide bonds are formed (correct)
  • The triple helix unwinds
  • Procollagen is formed
  • Amino-terminal globular domains fold

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