Podcast
Questions and Answers
What percentage of total body weight is composed of extracellular water?
What percentage of total body weight is composed of extracellular water?
- 30%
- 20% (correct)
- 40%
- 10%
Which of the following cations is predominant in the extracellular fluid compartment?
Which of the following cations is predominant in the extracellular fluid compartment?
- Calcium
- Magnesium
- Potassium
- Sodium (correct)
Which fluid compartment comprises approximately 40% of an individual’s total body weight?
Which fluid compartment comprises approximately 40% of an individual’s total body weight?
- Intracellular fluid (correct)
- Extracellular fluid
- Interstitial fluid
- Plasma
What is the primary anion found in the intracellular fluid compartment?
What is the primary anion found in the intracellular fluid compartment?
The concentration gradient between intracellular and extracellular compartments is maintained primarily by which mechanism?
The concentration gradient between intracellular and extracellular compartments is maintained primarily by which mechanism?
What are the three functional fluid compartments defined in the management of body fluids?
What are the three functional fluid compartments defined in the management of body fluids?
Which of the following best describes the term 'Total Body Water' (TBW) in fluid management?
Which of the following best describes the term 'Total Body Water' (TBW) in fluid management?
How is the classification of body fluid changes important in the surgical patient?
How is the classification of body fluid changes important in the surgical patient?
What is the significance of understanding 'acid-base balance' in surgical fluid management?
What is the significance of understanding 'acid-base balance' in surgical fluid management?
Which aspect of fluid management is particularly important for enhanced recovery after surgery (ERAS) pathways?
Which aspect of fluid management is particularly important for enhanced recovery after surgery (ERAS) pathways?
Flashcards
Total Body Water (TBW)
Total Body Water (TBW)
The amount of water in the human body, comprising approximately 50-60% of total body weight.
Extracellular Fluid (ECF)
Extracellular Fluid (ECF)
The fluid outside of cells, comprising interstitial fluids and plasma. About one-third of total body water.
Serum Osmolality
Serum Osmolality
Concentration of solutes in blood serum, calculated using sodium, glucose and BUN.
Calculated serum osmolality formula
Calculated serum osmolality formula
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Fluid Imbalance (surgical patient)
Fluid Imbalance (surgical patient)
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Insensible water loss
Insensible water loss
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Fluid Management (surgical)
Fluid Management (surgical)
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Enhanced Recovery After Surgery (ERAS)
Enhanced Recovery After Surgery (ERAS)
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Extracellular volume deficit
Extracellular volume deficit
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Daily Water Intake
Daily Water Intake
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Study Notes
Fluid and Electrolyte Management Overview
- Management of fluid and electrolytes is vital for surgical patient care.
- Fluid volume and electrolyte composition change preoperatively, intraoperatively, and postoperatively due to trauma and sepsis.
- Understanding normal body fluid anatomy helps in addressing pathologic shifts.
Body Fluids Composition
- Total Body Water (TBW) represents 50-60% of total body weight.
- TBW is divided into plasma (5% of body weight), interstitial fluid (15%), and intracellular fluid (40%).
- Extracellular fluids (ECF) account for about one-third of TBW.
Fluid Compartments and Distribution
- The extracellular water makes up 20% of total body weight.
- Young, lean males have a higher proportion of body weight as water compared to elderly or obese individuals.
- The concentration gradient between compartments maintained by sodium-potassium pumps influences fluid balance.
Osmotic Pressure
- Osmotic pressure is determined by the number of osmotically active particles (measured in osmoles).
- Serum osmolality is calculated using sodium, glucose, and BUN:
- Calculated serum osmolality = 2 sodium + (glucose/18) + (BUN/2.8).
- Osmolality in intracellular and extracellular fluids is maintained between 290 and 310 mOsm.
Fluid Management Strategies
- Preoperative, intraoperative, and postoperative fluid management is crucial for homeostasis.
- Enhanced Recovery After Surgery (ERAS) focuses on minimizing fluid administration and promoting early enteral intake to lower morbidity.
- Alternative resuscitative fluids currently have limited clinical utility but are being studied for specific electrolyte corrections.
Disturbances in Fluid Balance
- The most common fluid disorder in surgical patients is extracellular volume deficit, which may be acute or chronic.
- Acute volume deficit has implications for cardiovascular and neurological function.
- Fluid balance disturbances can be categorized into alterations in volume, concentration, and composition.
Daily Water and Electrolyte Exchange
- Average daily water intake is approximately 2000 mL; 75% from oral sources.
- Daily water loss includes 800-1200 mL through urine, 250 mL through stool, and 600 mL through insensible losses (skin and lungs).
- Insensible losses can increase with fever, hypermetabolism, and hyperventilation.
Specific Patient Considerations
- Fluid management must be tailored for specific conditions such as acute renal failure, cancer, malnutrition, and neurologic patients.
- Understanding the balance and needs of each patient type helps prevent complications associated with fluid and electrolyte imbalances.
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