Fluid and Electrolyte Balance Quiz

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Questions and Answers

What is Trousseau's Sign used to indicate?

  • Hypocalcemia (correct)
  • Hypercalcemia
  • Hyperphosphatemia
  • Hypophosphatemia

Which of the following conditions is associated with the mnemonic 'moans, bones, stones, and thrones'?

  • Hyperphosphatemia
  • Hypercalcemia (correct)
  • Hypophosphatemia
  • Hypocalcemia

What symptom is NOT commonly associated with hypocalcemia?

  • Psychosis (correct)
  • Weak bones
  • Muscle spasms
  • Numbness

In hypophosphatemia, which of the following symptoms may occur?

<p>Fatigue (B)</p> Signup and view all the answers

What is the typical phosphate level range?

<p>2.5-4.5 mg/dL (C)</p> Signup and view all the answers

Which of the following is a cause of hyperphosphatemia?

<p>Cell catabolism (C)</p> Signup and view all the answers

What condition results from an inverse relationship with calcium levels?

<p>Hypophosphatemia (D)</p> Signup and view all the answers

What is the normal range for magnesium (Mg^2+^) levels in mEq/L?

<p>1.3-2.1 mEq/L (B)</p> Signup and view all the answers

Which of the following is NOT a symptom of hypermagnesemia?

<p>Hyperactive deep tendon reflexes (A)</p> Signup and view all the answers

What role does magnesium play in blood pressure regulation?

<p>Assists in regulating blood pressure (D)</p> Signup and view all the answers

Which of the following conditions is often associated with hypomagnesemia?

<p>Celiac disease (B)</p> Signup and view all the answers

What is the primary cause of hypermagnesemia?

<p>Renal disease (A)</p> Signup and view all the answers

Which buffer system provides an immediate response to acid-base imbalances?

<p>Serum buffer system (A)</p> Signup and view all the answers

What impact does increased CO2 levels have on breathing rate?

<p>Increase in breathing rate (A)</p> Signup and view all the answers

In metabolic alkalosis, how is bicarbonate (HCO3^-) typically affected?

<p>High (A)</p> Signup and view all the answers

Which of the following accurately describes the anion gap in acidosis?

<p>It is high in acidosis (B)</p> Signup and view all the answers

What is the primary function of cultural testing in a laboratory setting?

<p>To identify the specific bacteria present in a patient sample (D)</p> Signup and view all the answers

Which of the following best describes active tuberculosis?

<p>Bacteria escape immune containment leading to infection (C)</p> Signup and view all the answers

Which primary lymphoid organ is primarily responsible for T-cell maturation?

<p>Thymus (D)</p> Signup and view all the answers

What does incidence refer to in epidemiology?

<p>The rate of new cases occurring in a specific time period (D)</p> Signup and view all the answers

Which of these is NOT a risk factor for developing tuberculosis?

<p>A strong immune system (A)</p> Signup and view all the answers

What key characteristic differentiates Gram-positive bacteria from Gram-negative bacteria?

<p>Thick peptidoglycan layer in the cell wall (D)</p> Signup and view all the answers

Which of the following factors can influence the progression of infections?

<p>Age and nutritional status (D)</p> Signup and view all the answers

What type of infection may become inactive but has the potential to reactivate later?

<p>Latent infection (D)</p> Signup and view all the answers

What does the Gram stain test primarily help to determine?

<p>The type of antibiotic to treat an infection (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of Gram-negative bacteria?

<p>Retain crystal violet stain (B)</p> Signup and view all the answers

What type of test identifies the specific bacteria present in a sample?

<p>Culture (B)</p> Signup and view all the answers

Which of the following examples is a Gram-positive bacterium?

<p>Staphylococcus aureus (A)</p> Signup and view all the answers

What feature of Gram-negative bacteria makes them more susceptible to certain antibiotics?

<p>Presence of an outer membrane (D)</p> Signup and view all the answers

Which pathogen is known to cause a chronic infection without acute symptoms?

<p>Herpes simplex virus (B)</p> Signup and view all the answers

What method is used to determine which antibiotics are most effective against a bacterial infection?

<p>Sensitivity testing (C)</p> Signup and view all the answers

What is the normal range for arterial bicarbonate (HCO3)?

<p>22-26 mEq/L (C)</p> Signup and view all the answers

Which step comes first in interpreting arterial blood gases (ABGs)?

<p>What is the pH? (D)</p> Signup and view all the answers

Which type of pathogen is specifically characterized as single-celled organisms that can cause harm?

<p>Protozoa (D)</p> Signup and view all the answers

What shape is characteristic of bacilli bacteria?

<p>Rod-shaped (A)</p> Signup and view all the answers

In the viral infection process, what is the term for the step where the viral coat is removed?

<p>Uncoating (C)</p> Signup and view all the answers

What is the normal range for partial pressure of arterial carbon dioxide (PaCO2)?

<p>35-45 mmHg (A)</p> Signup and view all the answers

Which of the following is NOT a type of bacteria listed?

<p>Candida (D)</p> Signup and view all the answers

What is the main distinction of fungi compared to other pathogens?

<p>They can form multicellular structures (B)</p> Signup and view all the answers

Which of the following pathogens undergoes a replication phase where it takes over the host's cellular machinery?

<p>Viruses (B)</p> Signup and view all the answers

What is the final step in the viral infection process?

<p>Release (D)</p> Signup and view all the answers

Flashcards

What is Trousseau's Sign?

Trousseau's sign is a clinical test for hypocalcemia. Pressing on the brachial artery for a few minutes causes a spasm (contraction) of the hand and fingers.

What is Chvostek's Sign?

Chvostek's sign is a clinical test for hypocalcemia. Tapping lightly on the facial nerve causes a twitch of the facial muscles.

What is hypocalcemia?

Hypocalcemia means low calcium levels in the blood. Symptoms include tingling, muscle spasms, weak bones.

What is hypercalcemia?

Hypercalcemia means high levels of calcium in the blood.

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What is the mnemonic for hypercalcemia?

The mnemonic "moans, bones, stones, and thrones" summarizes the effects of hypercalcemia: Moans refer to CNS effects such as fatigue, memory loss. Bones are associated with painful conditions like osteitis fibrosa cystica. Stones refer to calcium-based kidney stones. Thrones indicate GI symptoms like nausea, vomiting.

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What is hypophosphatemia?

Hypophosphatemia is low levels of phosphate in the blood.

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What is hyperphosphatemia?

Hyperphosphatemia is high levels of phosphate in the blood.

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What is magnesium and what are its key functions?

Magnesium is an important mineral that plays a role in regulating blood pressure, enzymatic reactions, and muscle relaxation. Its blood concentration is primarily regulated by the kidneys, with the help of parathyroid hormone (PTH) and Vitamin D.

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What is hypermagnesemia?

Hypermagnesemia is a condition where there is too much magnesium in the blood. It commonly occurs due to kidney dysfunction or excessive intake of magnesium-containing laxatives or medications.

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What are the signs and symptoms of hypermagnesemia?

Symptoms of hypermagnesemia include nausea, vomiting, altered consciousness, low blood pressure, flushing, and headaches.

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What is hypomagnesemia?

Hypomagnesemia refers to a deficiency of magnesium in the blood. It frequently occurs due to conditions like celiac disease, Crohn's disease, malnutrition, alcoholism, or certain medications.

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What are the signs and symptoms of hypomagnesemia?

Signs and symptoms of hypomagnesemia include hyperactive reflexes, slow bowel movements, constipation, and agitation.

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What is a buffer system?

A buffer system is a mechanism that resists changes in pH. In the body, it helps to maintain acid-base balance.

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What is the serum buffer system?

The serum buffer system is the immediate response to changes in pH, happening within seconds. It involves bases neutralizing acids, proteins binding to hydrogen ions, and potassium exchanging for hydrogen.

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What is the respiratory buffer system?

The respiratory buffer system operates within minutes to hours, adjusting the breathing rate to regulate carbon dioxide levels. Increased carbon dioxide triggers faster breathing, while decreased carbon dioxide leads to slower breathing.

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What is the renal buffer system?

The renal buffer system takes 2-3 days to respond and continuously regulates pH by producing and recycling bicarbonate, filtering and excreting excess hydrogen ions, and combining ammonia with hydrogen to form ammonium.

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Pathogens

Organisms that cause disease in a host.

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Cocci

Round-shaped bacteria.

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Bacilli

Rod-shaped bacteria.

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Spirilla

Spiral-shaped bacteria.

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Virus

A type of pathogen that causes disease in a host.

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Protozoa

Single-celled organisms that can cause harm to a host.

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Mycotic infection

A type of fungal infection.

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Helminths

Parasitic worms that can cause illness in a host.

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Viral infection

The process by which a virus enters a host cell and begins to replicate.

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Attachment

The attachment of a virus to a host cell is the first step in the process of viral infection.

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What is a chronic infection?

An infection that persists in the host for a long time without complete resolution, often without causing acute symptoms.

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What is a latent infection?

A type of infection where the pathogen is present but inactive, with the potential to reactivate later.

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What is a Gram stain?

A test that categorizes bacteria based on their cell wall structure, influencing antibiotic choice.

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What is bacterial culture?

A method of growing bacteria in a controlled environment to identify their species.

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What is antibiotic sensitivity testing?

A test that determines which antibiotics are most effective against a specific bacterial infection.

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What is a Gram-positive bacteria?

A group of bacteria characterized by a thick peptidoglycan layer in their cell walls, which retains crystal violet stain and makes them appear purple under a microscope.

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What is a Gram-negative bacteria?

Bacteria with a thin peptidoglycan layer and an outer membrane containing lipopolysaccharides, which do not retain crystal violet stain and appear pink/red under a microscope.

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Give examples of Gram-positive bacteria.

Examples of Gram-positive bacteria include Staphylococcus aureus, Streptococcus pneumoniae, and Bacillus subtilis.

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Give examples of Gram-negative bacteria.

Examples of Gram-negative bacteria include Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi.

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What is tuberculosis?

A bacterial infection primarily affecting the lungs, caused by Mycobacterium tuberculosis.

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What is Latent TB?

WBCs isolate and contain the bacteria, preventing it from spreading.

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What is Active TB?

TB bacteria can escape from containment, leading to active infection.

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What is bone marrow?

The primary site of hematopoiesis, where all immune cells are produced and B-cells mature.

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What is the thymus?

This organ is the site of T-cell maturation and shrinks from puberty onward.

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Study Notes

Fluid and Electrolyte Regulation

  • Renin-Angiotensin-Aldosterone System (RAAS): Increased plasma volume, blood pressure, vascular tone, and cardiac output are the overall effects.
  • Renin: Released by the kidneys, it triggers a cascade of events.
  • Angiotensin I: Converted to angiotensin II in the lungs by ACE (Angiotensin-Converting Enzyme).
  • Angiotensin II: Increases blood pressure through vasoconstriction and stimulating aldosterone release.
  • Aldosterone: Regulates sodium reabsorption in the kidneys, leading to water retention and increased blood volume.
  • ADH (Antidiuretic Hormone): Increases water reabsorption in the kidneys.
  • ANP (Atrial Natriuretic Peptide) and BNP (Brain Natriuretic Peptide): Decrease blood pressure and volume.

Edema

  • Edema: Fluid accumulation in interstitial spaces.
  • Causes of Edema: Increased hydrostatic pressure or decreased oncotic pressure. This can be due to conditions like heart failure, hypertension.
  • Hydrostatic pressure: Pushes fluid out of blood vessels.
  • Oncotic pressure: Pulling force exerted by proteins (e.g., albumin) within blood vessels, draws fluid back in. A decrease in albumin is a likely cause.
  • Vascular permeability: Increased permeability allows fluid and cells to leak into tissues.

Electrolytes: Sodium (Na+) and Potassium (K+)

  • Sodium (Na+): 135-145 mEq/L. Key for fluid balance and nerve impulse transmission.

  • Hyponatremia: Sodium level below 135 mEq/L. Symptoms include muscle weakness and confusion.

  • Hypernatremia: Sodium level above 145 mEq/L. Symptoms include thirst, lethargy, and potentially seizures or coma.

  • Potassium (K+): 3.5-5.0 mEq/L. Crucial for maintaining the electrical gradient across cell membranes to conduct nerve impulses, muscle contractions, and many biochemical processes.

  • Hypokalemia: Potassium level below 3.5 mEq/L. Symptoms include muscle weakness, confusion, and cardiac arrhythmias.

  • Hyperkalemia: Potassium level above 5 mEq/L. Symptoms include muscle weakness, paralysis, and cardiac arrest.

Electrolytes: Calcium (Ca2+), Phosphate (PO4), and Magnesium (Mg2+)

  • Calcium (Ca2+): Role in muscle contraction, nerve transmission, and blood clotting. Normal range: 9.0-10.5 mEq/L.
  • Hypocalcemia: Calcium level below the normal range. Symptoms include muscle spasms and tetany.
  • Hypercalcemia: Calcium level above the normal range. Symptoms include fatigue, kidney stones, and potentially cardiac arrhythmias.
  • Phosphate (PO4): Critical for bone health and energy production, Inverse relationship with calcium. Normal range: 2.5-4.5 mg/dL.
  • Hypophosphatemia: Phosphate level below normal range, causing weakness, and bone pain.
  • Hyperphosphatemia: Phosphate level above the normal range. Symptoms include itching, muscle and joint pain.
  • Magnesium (Mg2+): Involved in various biological processes including muscle function, blood pressure regulation and protein synthesis. Normal range: 1.3-2.1 mEq/L.

Acid-Base Balance

  • Buffer system maintains pH through various components.
  • Respiratory system regulates CO2 levels, altering breathing rate.
  • Renal system regulates HCO3- (bicarbonate) levels.
  • Metabolic acidosis pH < 7.35.
  • Metabolic alkalosis pH > 7.45.
  • Respiratory acidosis increased CO2, decreased pH.
  • Respiratory alkalosis decreased CO2, increased pH.

Acid-Base Imbalances - Clinical Scenarios

  • Diagnosis of imbalances relies on arterial blood gas (ABG) values to assess pH, PaCO2 and HCO3.

Urinary Tract Infections (UTIs)

  • UTIs: Infections of the urinary tract.
  • Symptoms: dysuria (painful urination), frequency, urgency, cloudy or bloody urine.
  • Risk factors: Diabetes, immunodeficiency, etc.

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