Podcast
Questions and Answers
What is Trousseau's Sign used to indicate?
What is Trousseau's Sign used to indicate?
- Hypocalcemia (correct)
- Hypercalcemia
- Hyperphosphatemia
- Hypophosphatemia
Which of the following conditions is associated with the mnemonic 'moans, bones, stones, and thrones'?
Which of the following conditions is associated with the mnemonic 'moans, bones, stones, and thrones'?
- Hyperphosphatemia
- Hypercalcemia (correct)
- Hypophosphatemia
- Hypocalcemia
What symptom is NOT commonly associated with hypocalcemia?
What symptom is NOT commonly associated with hypocalcemia?
- Psychosis (correct)
- Weak bones
- Muscle spasms
- Numbness
In hypophosphatemia, which of the following symptoms may occur?
In hypophosphatemia, which of the following symptoms may occur?
What is the typical phosphate level range?
What is the typical phosphate level range?
Which of the following is a cause of hyperphosphatemia?
Which of the following is a cause of hyperphosphatemia?
What condition results from an inverse relationship with calcium levels?
What condition results from an inverse relationship with calcium levels?
What is the normal range for magnesium (Mg^2+^) levels in mEq/L?
What is the normal range for magnesium (Mg^2+^) levels in mEq/L?
Which of the following is NOT a symptom of hypermagnesemia?
Which of the following is NOT a symptom of hypermagnesemia?
What role does magnesium play in blood pressure regulation?
What role does magnesium play in blood pressure regulation?
Which of the following conditions is often associated with hypomagnesemia?
Which of the following conditions is often associated with hypomagnesemia?
What is the primary cause of hypermagnesemia?
What is the primary cause of hypermagnesemia?
Which buffer system provides an immediate response to acid-base imbalances?
Which buffer system provides an immediate response to acid-base imbalances?
What impact does increased CO2 levels have on breathing rate?
What impact does increased CO2 levels have on breathing rate?
In metabolic alkalosis, how is bicarbonate (HCO3^-) typically affected?
In metabolic alkalosis, how is bicarbonate (HCO3^-) typically affected?
Which of the following accurately describes the anion gap in acidosis?
Which of the following accurately describes the anion gap in acidosis?
What is the primary function of cultural testing in a laboratory setting?
What is the primary function of cultural testing in a laboratory setting?
Which of the following best describes active tuberculosis?
Which of the following best describes active tuberculosis?
Which primary lymphoid organ is primarily responsible for T-cell maturation?
Which primary lymphoid organ is primarily responsible for T-cell maturation?
What does incidence refer to in epidemiology?
What does incidence refer to in epidemiology?
Which of these is NOT a risk factor for developing tuberculosis?
Which of these is NOT a risk factor for developing tuberculosis?
What key characteristic differentiates Gram-positive bacteria from Gram-negative bacteria?
What key characteristic differentiates Gram-positive bacteria from Gram-negative bacteria?
Which of the following factors can influence the progression of infections?
Which of the following factors can influence the progression of infections?
What type of infection may become inactive but has the potential to reactivate later?
What type of infection may become inactive but has the potential to reactivate later?
What does the Gram stain test primarily help to determine?
What does the Gram stain test primarily help to determine?
Which of the following is NOT a characteristic of Gram-negative bacteria?
Which of the following is NOT a characteristic of Gram-negative bacteria?
What type of test identifies the specific bacteria present in a sample?
What type of test identifies the specific bacteria present in a sample?
Which of the following examples is a Gram-positive bacterium?
Which of the following examples is a Gram-positive bacterium?
What feature of Gram-negative bacteria makes them more susceptible to certain antibiotics?
What feature of Gram-negative bacteria makes them more susceptible to certain antibiotics?
Which pathogen is known to cause a chronic infection without acute symptoms?
Which pathogen is known to cause a chronic infection without acute symptoms?
What method is used to determine which antibiotics are most effective against a bacterial infection?
What method is used to determine which antibiotics are most effective against a bacterial infection?
What is the normal range for arterial bicarbonate (HCO3)?
What is the normal range for arterial bicarbonate (HCO3)?
Which step comes first in interpreting arterial blood gases (ABGs)?
Which step comes first in interpreting arterial blood gases (ABGs)?
Which type of pathogen is specifically characterized as single-celled organisms that can cause harm?
Which type of pathogen is specifically characterized as single-celled organisms that can cause harm?
What shape is characteristic of bacilli bacteria?
What shape is characteristic of bacilli bacteria?
In the viral infection process, what is the term for the step where the viral coat is removed?
In the viral infection process, what is the term for the step where the viral coat is removed?
What is the normal range for partial pressure of arterial carbon dioxide (PaCO2)?
What is the normal range for partial pressure of arterial carbon dioxide (PaCO2)?
Which of the following is NOT a type of bacteria listed?
Which of the following is NOT a type of bacteria listed?
What is the main distinction of fungi compared to other pathogens?
What is the main distinction of fungi compared to other pathogens?
Which of the following pathogens undergoes a replication phase where it takes over the host's cellular machinery?
Which of the following pathogens undergoes a replication phase where it takes over the host's cellular machinery?
What is the final step in the viral infection process?
What is the final step in the viral infection process?
Flashcards
What is Trousseau's Sign?
What is Trousseau's Sign?
Trousseau's sign is a clinical test for hypocalcemia. Pressing on the brachial artery for a few minutes causes a spasm (contraction) of the hand and fingers.
What is Chvostek's Sign?
What is Chvostek's Sign?
Chvostek's sign is a clinical test for hypocalcemia. Tapping lightly on the facial nerve causes a twitch of the facial muscles.
What is hypocalcemia?
What is hypocalcemia?
Hypocalcemia means low calcium levels in the blood. Symptoms include tingling, muscle spasms, weak bones.
What is hypercalcemia?
What is hypercalcemia?
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What is the mnemonic for hypercalcemia?
What is the mnemonic for hypercalcemia?
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What is hypophosphatemia?
What is hypophosphatemia?
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What is hyperphosphatemia?
What is hyperphosphatemia?
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What is magnesium and what are its key functions?
What is magnesium and what are its key functions?
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What is hypermagnesemia?
What is hypermagnesemia?
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What are the signs and symptoms of hypermagnesemia?
What are the signs and symptoms of hypermagnesemia?
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What is hypomagnesemia?
What is hypomagnesemia?
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What are the signs and symptoms of hypomagnesemia?
What are the signs and symptoms of hypomagnesemia?
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What is a buffer system?
What is a buffer system?
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What is the serum buffer system?
What is the serum buffer system?
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What is the respiratory buffer system?
What is the respiratory buffer system?
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What is the renal buffer system?
What is the renal buffer system?
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Pathogens
Pathogens
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Cocci
Cocci
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Bacilli
Bacilli
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Spirilla
Spirilla
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Virus
Virus
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Protozoa
Protozoa
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Mycotic infection
Mycotic infection
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Helminths
Helminths
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Viral infection
Viral infection
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Attachment
Attachment
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What is a chronic infection?
What is a chronic infection?
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What is a latent infection?
What is a latent infection?
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What is a Gram stain?
What is a Gram stain?
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What is bacterial culture?
What is bacterial culture?
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What is antibiotic sensitivity testing?
What is antibiotic sensitivity testing?
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What is a Gram-positive bacteria?
What is a Gram-positive bacteria?
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What is a Gram-negative bacteria?
What is a Gram-negative bacteria?
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Give examples of Gram-positive bacteria.
Give examples of Gram-positive bacteria.
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Give examples of Gram-negative bacteria.
Give examples of Gram-negative bacteria.
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What is tuberculosis?
What is tuberculosis?
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What is Latent TB?
What is Latent TB?
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What is Active TB?
What is Active TB?
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What is bone marrow?
What is bone marrow?
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What is the thymus?
What is the thymus?
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Study Notes
Fluid and Electrolyte Regulation
- Renin-Angiotensin-Aldosterone System (RAAS): Increased plasma volume, blood pressure, vascular tone, and cardiac output are the overall effects.
- Renin: Released by the kidneys, it triggers a cascade of events.
- Angiotensin I: Converted to angiotensin II in the lungs by ACE (Angiotensin-Converting Enzyme).
- Angiotensin II: Increases blood pressure through vasoconstriction and stimulating aldosterone release.
- Aldosterone: Regulates sodium reabsorption in the kidneys, leading to water retention and increased blood volume.
- ADH (Antidiuretic Hormone): Increases water reabsorption in the kidneys.
- ANP (Atrial Natriuretic Peptide) and BNP (Brain Natriuretic Peptide): Decrease blood pressure and volume.
Edema
- Edema: Fluid accumulation in interstitial spaces.
- Causes of Edema: Increased hydrostatic pressure or decreased oncotic pressure. This can be due to conditions like heart failure, hypertension.
- Hydrostatic pressure: Pushes fluid out of blood vessels.
- Oncotic pressure: Pulling force exerted by proteins (e.g., albumin) within blood vessels, draws fluid back in. A decrease in albumin is a likely cause.
- Vascular permeability: Increased permeability allows fluid and cells to leak into tissues.
Electrolytes: Sodium (Na+) and Potassium (K+)
-
Sodium (Na+): 135-145 mEq/L. Key for fluid balance and nerve impulse transmission.
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Hyponatremia: Sodium level below 135 mEq/L. Symptoms include muscle weakness and confusion.
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Hypernatremia: Sodium level above 145 mEq/L. Symptoms include thirst, lethargy, and potentially seizures or coma.
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Potassium (K+): 3.5-5.0 mEq/L. Crucial for maintaining the electrical gradient across cell membranes to conduct nerve impulses, muscle contractions, and many biochemical processes.
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Hypokalemia: Potassium level below 3.5 mEq/L. Symptoms include muscle weakness, confusion, and cardiac arrhythmias.
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Hyperkalemia: Potassium level above 5 mEq/L. Symptoms include muscle weakness, paralysis, and cardiac arrest.
Electrolytes: Calcium (Ca2+), Phosphate (PO4), and Magnesium (Mg2+)
- Calcium (Ca2+): Role in muscle contraction, nerve transmission, and blood clotting. Normal range: 9.0-10.5 mEq/L.
- Hypocalcemia: Calcium level below the normal range. Symptoms include muscle spasms and tetany.
- Hypercalcemia: Calcium level above the normal range. Symptoms include fatigue, kidney stones, and potentially cardiac arrhythmias.
- Phosphate (PO4): Critical for bone health and energy production, Inverse relationship with calcium. Normal range: 2.5-4.5 mg/dL.
- Hypophosphatemia: Phosphate level below normal range, causing weakness, and bone pain.
- Hyperphosphatemia: Phosphate level above the normal range. Symptoms include itching, muscle and joint pain.
- Magnesium (Mg2+): Involved in various biological processes including muscle function, blood pressure regulation and protein synthesis. Normal range: 1.3-2.1 mEq/L.
Acid-Base Balance
- Buffer system maintains pH through various components.
- Respiratory system regulates CO2 levels, altering breathing rate.
- Renal system regulates HCO3- (bicarbonate) levels.
- Metabolic acidosis pH < 7.35.
- Metabolic alkalosis pH > 7.45.
- Respiratory acidosis increased CO2, decreased pH.
- Respiratory alkalosis decreased CO2, increased pH.
Acid-Base Imbalances - Clinical Scenarios
- Diagnosis of imbalances relies on arterial blood gas (ABG) values to assess pH, PaCO2 and HCO3.
Urinary Tract Infections (UTIs)
- UTIs: Infections of the urinary tract.
- Symptoms: dysuria (painful urination), frequency, urgency, cloudy or bloody urine.
- Risk factors: Diabetes, immunodeficiency, etc.
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