Flavivirus Structure and Transmission Quiz
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Questions and Answers

What is the size of the spherical enveloped particle of the Flavivirus genus?

  • 75nm in diameter
  • 100nm in diameter
  • 25nm in diameter
  • 50nm in diameter (correct)

How are the envelope glycoproteins arranged in the Flavivirus virion?

  • With helical symmetry
  • Randomly distributed
  • In a linear pattern
  • With icosahedral symmetry (correct)

What is the mode of transmission for the Flavivirus genus?

  • Transmitted through contaminated water
  • Direct contact with infected individuals
  • Airborne transmission
  • Transmitted by arthropods (arboviruses) (correct)

How many copies of M and E (envelope protein heterodimers) are present in mature viral particles of the Flavivirus genus?

<p>180 copies (B)</p> Signup and view all the answers

Which viral protein is responsible for encapsidation of the Flavivirus genome RNA?

<p>C protein (C)</p> Signup and view all the answers

What is the role of the prM protein in Flavivirus virion assembly?

<p>Protects E from premature conformational change (C)</p> Signup and view all the answers

Which domain of the Flavivirus E protein is responsible for receptor binding?

<p>Domain I (B)</p> Signup and view all the answers

What is the primary entry mechanism for Flaviviruses into host cells?

<p>Endocytosis within clathrin-coated vesicles (A)</p> Signup and view all the answers

What is the role of NS3 protein in Flavivirus replication?

<p>Nucleoside triphosphatase and helicase activities (D)</p> Signup and view all the answers

What happens to the pr peptide during Flavivirus virion assembly?

<p>'pr' peptide is released extracellularly (C)</p> Signup and view all the answers

Where does RNA synthesis occur during Flavivirus replication?

<p>Cytoplasm (A)</p> Signup and view all the answers

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