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Flavivirus Structure and Transmission Quiz

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Questions and Answers

What is the size of the spherical enveloped particle of the Flavivirus genus?

75nm in diameter
100nm in diameter
25nm in diameter
50nm in diameter (correct)

How are the envelope glycoproteins arranged in the Flavivirus virion?

With helical symmetry
Randomly distributed
In a linear pattern
With icosahedral symmetry (correct)

What is the mode of transmission for the Flavivirus genus?

Transmitted through contaminated water
Direct contact with infected individuals
Airborne transmission
Transmitted by arthropods (arboviruses) (correct)

How many copies of M and E (envelope protein heterodimers) are present in mature viral particles of the Flavivirus genus?

180 copies (B) Signup and view all the answers

Which viral protein is responsible for encapsidation of the Flavivirus genome RNA?

C protein (C) Signup and view all the answers

What is the role of the prM protein in Flavivirus virion assembly?

Protects E from premature conformational change (C) Signup and view all the answers

Which domain of the Flavivirus E protein is responsible for receptor binding?

Domain I (B) Signup and view all the answers

What is the primary entry mechanism for Flaviviruses into host cells?

Endocytosis within clathrin-coated vesicles (A) Signup and view all the answers

What is the role of NS3 protein in Flavivirus replication?

Nucleoside triphosphatase and helicase activities (D) Signup and view all the answers

What happens to the pr peptide during Flavivirus virion assembly?

'pr' peptide is released extracellularly (C) Signup and view all the answers

Where does RNA synthesis occur during Flavivirus replication?

Cytoplasm (A) Signup and view all the answers

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