Podcast
Questions and Answers
What is the resting zone?
What is the resting zone?
Area of cartilage on epiphyseal side of epiphyseal plate that is relatively inactive
What happens in the proliferation (growth) zone?
What happens in the proliferation (growth) zone?
- Chondrocytes die
- Chondrocytes rapidly divide (correct)
- Osteoclasts clean up
- Cartilage becomes calcified
Describe the hypertrophic zone.
Describe the hypertrophic zone.
Area with older chondrocytes closer to diaphysis where cartilage lacunae enlarge and erode, forming interconnecting spaces.
What occurs in the calcification zone?
What occurs in the calcification zone?
Which processes take place in the ossification zone?
Which processes take place in the ossification zone?
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Study Notes
Five Zones of Epiphyseal Plate
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Resting Zone: Located on the epiphyseal side; primarily inactive cartilage area; serves as a base for the other zones.
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Proliferation (Growth) Zone: Found on the diaphysis side; rapidly dividing cartilage; new cells push the epiphysis away from the diaphysis, contributing to bone lengthening.
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Hypertrophic Zone: Contains older chondrocytes near the diaphysis; cartilage lacunae expand and erode, leading to the formation of interconnecting spaces.
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Calcification Zone: A process where the surrounding cartilage matrix undergoes calcification; results in the death and deterioration of chondrocytes.
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Ossification Zone: Characterized by the deterioration of chondrocytes; calcified cartilage at the epiphyseal-diaphysis junction; osteoclasts remove debris while osteoblasts secrete osteoid; marks the transition to spongy bone formation and the enlargement of the medullary cavity.
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