Podcast
Questions and Answers
What is the characteristic feature of the structure of fibril-forming collagen?
What is the characteristic feature of the structure of fibril-forming collagen?
- Elongated, triple-helical structure stabilized by interchain hydrogen bonds (correct)
- Globular structure with a hydrophobic core
- Ropelike structure with a beta-pleated sheet
- Pleated structure with a charged surface
What is responsible for the 'kinks' in the peptide chain of collagen?
What is responsible for the 'kinks' in the peptide chain of collagen?
- Hydroxyproline residues
- Hydroxylysine residues
- Glycine residues
- Proline residues (correct)
What is the function of hydroxyproline and hydroxylysine in collagen?
What is the function of hydroxyproline and hydroxylysine in collagen?
- To provide a charged surface
- To stabilize the triple helical structure (correct)
- To increase the tensile strength of collagen
- To facilitate the formation of disulfide bonds
What is the site of glycosylation in collagen?
What is the site of glycosylation in collagen?
Which of the following tissues is characterized by the presence of fibril-associated collagen?
Which of the following tissues is characterized by the presence of fibril-associated collagen?
What is the first step in the biosynthesis of collagen?
What is the first step in the biosynthesis of collagen?
What is the first step in the synthesis of collagen?
What is the first step in the synthesis of collagen?
What is the role of procollagen peptidases in collagen synthesis?
What is the role of procollagen peptidases in collagen synthesis?
What is the characteristic feature of Ehlers-Danlos syndrome?
What is the characteristic feature of Ehlers-Danlos syndrome?
What is the function of alpha-1 antitrypsin (AAT)?
What is the function of alpha-1 antitrypsin (AAT)?
What is the consequence of a deficiency in lysyl hydroxylase?
What is the consequence of a deficiency in lysyl hydroxylase?
What type of collagen is commonly associated with osteogenesis imperfecta?
What type of collagen is commonly associated with osteogenesis imperfecta?
What is the consequence of a mutation in the fibrillin-1 protein?
What is the consequence of a mutation in the fibrillin-1 protein?
What is the function of vitamin C in collagen synthesis?
What is the function of vitamin C in collagen synthesis?
What is the characteristic feature of scurvy?
What is the characteristic feature of scurvy?
What is the structure of elastin?
What is the structure of elastin?
