Recent Lessons

Show all results for ""

Feature Overview

Ace your exams with our all-in-one platform for creating and sharing quizzes and tests.

Quizzes

Create quizzes and tests automatically from your content using AI.

Flashcards

Automatically turn your notes into digital flashcards.

Share, Export & Embed

Share with classmates or export to Excel and your learning management system.

Stats & Reporting

Auto-grading quizzes and tests with detailed stats and reports.

Mobile Apps

The smarter way to study – wherever you are.

Pricing

Search...

16 Questions

0 Views

Fibrous Proteins: Structure and Types

Choose a study mode

Play Quiz

Study Flashcards

Spaced Repetition

Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary function of the fibril-associated collagens?

To provide tensile strength to skin

To form a ropelike structure

To link collagen fibrils together (correct)

To form a meshwork structure

What is the role of hydroxylation in collagen synthesis?

To modify lysine and proline residues after incorporation into polypeptide chains (correct)

To facilitate the formation of alpha helices

To inhibit the formation of collagen fibers

To increase the tensile strength of collagen

What is the function of glycine in the collagen triple helix?

To provide flexibility to the collagen fiber

To stabilize the triple helix through hydrogen bonding

To inhibit the formation of alpha helices

To facilitate the formation of kinks in the peptide chain (correct)

What is the characteristic structure of collagen?

Elongated, triple-helical structure Signup and view all the answers

What is the role of proline in the collagen triple helix?

To cause kinks in the peptide chain, facilitating the formation of the triple helix Signup and view all the answers

What is the first step in the biosynthesis of collagen?

Transcription of genes of pro-alpha 1 and pro-alpha 2 chains Signup and view all the answers

What is the function of lysyl hydroxylase in collagen production?

To hydroxylate selected proline and lysine residues Signup and view all the answers

What is the characteristics of type 1 osteogenesis imperfecta (OI)?

Characterized by mild bone fragility, hearing loss, and blue sclera Signup and view all the answers

What is the role of vitamin C in collagen production?

To hydroxylate proline and lysine residues Signup and view all the answers

What is the difference between elastin and collagen?

Elastin is rich in glycine, alanine, valine, proline, and lysine, while collagen is rich in hydroxylysine and hydroxyproline Signup and view all the answers

What is the function of alpha1-antitrypsin (AAT)?

To inhibit elastase released during phagocytosis by neutrophils in alveoli of lungs Signup and view all the answers

What is the characteristic of classic Ehlers-Danlos syndrome (EDS)?

Characterized by skin extensibility and fragility, and joint hypermobility Signup and view all the answers

What is the consequence of a deficiency of alpha1-antitrypsin (AAT)?

Emphysema and cirrhosis Signup and view all the answers

What is the role of procollagen peptidases in collagen production?

To cleave the N-terminal and C-terminal propeptides from procollagen Signup and view all the answers

What is the characteristic of Marfan syndrome?

Characterized by impaired structural integrity in skeleton, eye, and cardiovascular system Signup and view all the answers

What is the function of collagenases in collagen degradation?

To cleave collagen at specific sites, generating 3/4 and 1/4 length fragments Signup and view all the answers