Hemostasis and Thrombosis Terms Quiz

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What is hemostasis?

Hemostasis is the series of cellular and humoral systems that balance the flow of blood within the circulation and cause the cessation of blood flow.

What is thrombosis?

Thrombosis is the formation of a clot in a blood vessel, which can lead to the formation of a thrombus or emboli.

What is fibrinogen?

Fibrinogen is a plasma protein that is converted to fibrin, the active form, at the end of the coagulation cascade.

What are coagulation factors?

Coagulation factors, also known as procoagulants, are enzymes responsible for blood clotting. Signup and view all the answers

What are the types of hemostasis?

The types of hemostasis are primary and secondary. Signup and view all the answers

What are the five main events in hemostasis?

<ol> <li>Blood vessel constriction 2. Formation of platelet plug 3. Interaction of damaged blood vessels, platelets, and coagulation factors 4. Development of a blood clot 5. Fibrinolytic removal of fibrin clot</li> </ol> Signup and view all the answers

What are the three layers of blood vessels and their main components?

Tunica Intima (innermost) - Composed of endothelial cells with anti-thrombotic properties; Tunica Media (Middle) - Contains smooth muscles and connective tissue; Tunica Adventitia (outermost) - Composed of fibroblasts, collagen, and tissue factor Signup and view all the answers

What are the actions of the Tunica Intima in blood vessels?

It has anti-thrombotic properties, including the production of prostacyclin and nitric oxide, as well as the activation of Protein C through Thrombomodulin. Signup and view all the answers

What are the main components involved in intravascular hemostasis?

Platelets and coagulation factors Signup and view all the answers

What are the three main actions of platelets during hemostasis?

Adhesion, aggregation, and release of substances that promote hemostasis Signup and view all the answers

What is the end result of the coagulation process?

Fibrin clot formation Signup and view all the answers

Which component is responsible for blood clotting?

Coagulation factors Signup and view all the answers

What is the main function of fibrin during hemostasis?

To stop the bleeding Signup and view all the answers

Which type of hemostasis involves blood vessels contracting to reduce blood flow?

Primary hemostasis Signup and view all the answers

What is the role of platelets during the stoppage of bleeding in hemostasis?

To secrete granules and aggregate to form a platelet plug Signup and view all the answers

What is the first step in hemostasis?

Blood vessel constriction Signup and view all the answers

Which of the following is a component of the Tunica Intima in blood vessels?

Endothelial cells Signup and view all the answers

What is the primary action of Heparan Sulfate in hemostasis?

Antithrombin Signup and view all the answers

Which event involves the interaction of damaged blood vessels, platelets, and coagulation factors?

Secondary hemostasis Signup and view all the answers

What is the final step in hemostasis that involves the release of T-PA for fibrinolysis?

Fibrinolytic removal of fibrin clot Signup and view all the answers