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term 2 - week 6

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Questions and Answers

1-Primary cilia are made of:

Actin
Intermediate filaments
Tubulin (correct)
All of the above

The diameter of intermediate filaments is

2
7
10 (correct)
15

Dynamic instability (choose one correct answer):

Degrades a subset of intermediate filaments
. Is an important characteristic of the actin cytoskeleton
Is compensated by static stability
Is the co-existence of growing and shrinking microtubules in the same conditions (correct)

What changes does Cdc42 promote in the cell?

Filopodia (A) Signup and view all the answers

5- Primary cilia are:

microtubule based sensory organelles that detect mechanical and chemical stimuli (C) Signup and view all the answers

What is true about Lamins:

Contain a nuclear localization signal (NLS) to be imported into the nucleus b. They are components of the nuclear lamina c. They are intermediate filament proteins d. They are mutated the premature aging disease Hutchinson-Gilford progeria syndrome (D) Signup and view all the answers

How does the actin cytoskeleton contribute to cell movement?

Polymerization and depolymerization of actin filaments b. Providing tracks for the binding of myosin motor proteins. c. Forms filopodia and lamellipodia d. Provides binding sites for actin related proteins (Arps) that provide actin branching e. (D) Signup and view all the answers

To study the actin cytoskeleton we can use:

Inhibitors of actin polymerization and depolymerization (A) Signup and view all the answers

I need to move an organelle along the cell, what do I need?

ATP, a motor protein and a track (polarized cytoskeleton: actin or microtubules) (D) Signup and view all the answers

Myosin:

. Is a motor protein that uses ATP to walk along actin filaments (A) Signup and view all the answers

A cell is moving towards a cAMP gradient, what is it doing

b. Chemotaxis (B) Signup and view all the answers

Cells that attach to substrates using focal adhesions can move fast because:

. Focal adhesions are reversible and dynamic (A) Signup and view all the answers