10 Questions
What is the specialized layer of endometrium that forms the base of the placental bed?
Decidua
What induces endometrial stromal cells to undergo cellular modifications and vascular alterations termed the 'decidual reaction'?
Progesterone
What initiates implantation by breaching the surface epithelial lining of the decidua to attach and invade, leading to the formation of the placenta?
Trophoblast cells
Which part of the blastocyst gives rise to the embryo?
Inner cell mass
What is the term for the structural changes in both the blastocyst and endometrial wall that make implantation possible?
Decidualization
Which immune cells comprise approximately 70% of decidual leukocytes in the normal post-implantation decidua?
Natural Killer (NK) cells
What is the main purpose of interaction between maternal immune regulation and trophoblast-derived tolerogenic molecules at the feto-maternal interface?
To induce a tolerogenic environment
What is the term used to define three or more consecutive spontaneous miscarriages before the 20th week of pregnancy?
Recurrent spontaneous abortion (RSA)
What type of antibodies have been detected with high frequency in the sera of normal pregnant women?
Anti-paternal cytotoxic antibodies
What is the term used to describe the fetus due to the presence of antigens of maternal and paternal origin?
Semiallogenic
Test your knowledge on the early development of the embryo, including the formation of the inner cell mass and the trophectoderm which will give rise to the embryo and placenta respectively. This quiz covers concepts related to fetomaternal immunity and early stages of human embryonic development.
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