Fetal Lung Maturity Testing

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Questions and Answers

What is the most serious and life-threatening complication of a respiratory tract disorder?

  • Recurrent ear infections
  • Recurrent skin infections
  • Recurrent eye infections
  • Recurrent pulmonary infections (correct)

In airway epithelial cells, what is the layer between the apical surface and mucus called?

  • Airway surface liquid (ASL) (correct)
  • Periciliary liquid layer
  • Mucus layer
  • Gel layer

What happens to the depth of ASL when CFTR is defective?

  • It remains unaffected
  • It is depleted (correct)
  • It increases
  • It becomes static

What is the main function of CFTR in the airway epithelial cells?

<p>To allow chloride ions to be drawn from the cell and into the ASL (C)</p> Signup and view all the answers

What is the primary function of ENaC in the airway epithelial cells?

<p>To facilitate Na⁺ reabsorption across the apical membranes (A)</p> Signup and view all the answers

What is the consequence of sodium flowing freely from the ASL and into the cell?

<p>The cilia will be left in the mucous layer (D)</p> Signup and view all the answers

Which of the following is the primary cause of Respiratory Distress Syndrome (RDS) in preterm infants?

<p>Insufficient production of DPPC (B)</p> Signup and view all the answers

Which method is used to accelerate lung maturation in a mother before delivery?

<p>Giving the mother glucocorticoids (C)</p> Signup and view all the answers

What is the molecular ratio that indicates fetal lung maturity?

<p>DPPC to S ratio of 2 or above (C)</p> Signup and view all the answers

In adults, Respiratory Distress Syndrome can occur due to which of the following?

<p>Damage to surfactant-producing pneumocytes (C)</p> Signup and view all the answers

Which protein complex helps regulate excess elastase activity in the lungs during an infection?

<p>α1-antiproteinase and elastase complex (C)</p> Signup and view all the answers

What is the main cause of Respiratory Distress Syndrome (RDS) in preterm infants?

<p>Insufficient production of surfactant (A)</p> Signup and view all the answers

Which of the following methods is used to specifically prevent and treat Respiratory Distress Syndrome in newborn infants?

<p>Directly administering surfactant via intratracheal instillation (D)</p> Signup and view all the answers

What is the role of DPPC in preventing Respiratory Distress Syndrome (RDS) in preterm infants?

<p>It decreases the surface tension of the fluid layer lining the alveoli, aiding reinflation (B)</p> Signup and view all the answers

Which type of cells in the lungs produce and secrete DPPC, a crucial component of lung surfactant?

<p>Type II pneumocytes (D)</p> Signup and view all the answers

Which of the following is a potential treatment for Respiratory Distress Syndrome (RDS) in preterm infants?

<p>Administering exogenous surfactant (A)</p> Signup and view all the answers

What is the function of lung surfactant in adult lungs?

<p>To decrease surface tension of the fluid layer lining the alveoli, aiding reinflation (C)</p> Signup and view all the answers

What are the primary components of lung surfactant?

<p>Predominantly lipid with some protein and carbohydrate (D)</p> Signup and view all the answers

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