Fetal Lung Maturity Testing
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Questions and Answers

What is the most serious and life-threatening complication of a respiratory tract disorder?

  • Recurrent ear infections
  • Recurrent skin infections
  • Recurrent eye infections
  • Recurrent pulmonary infections (correct)
  • In airway epithelial cells, what is the layer between the apical surface and mucus called?

  • Airway surface liquid (ASL) (correct)
  • Periciliary liquid layer
  • Mucus layer
  • Gel layer
  • What happens to the depth of ASL when CFTR is defective?

  • It remains unaffected
  • It is depleted (correct)
  • It increases
  • It becomes static
  • What is the main function of CFTR in the airway epithelial cells?

    <p>To allow chloride ions to be drawn from the cell and into the ASL</p> Signup and view all the answers

    What is the primary function of ENaC in the airway epithelial cells?

    <p>To facilitate Na⁺ reabsorption across the apical membranes</p> Signup and view all the answers

    What is the consequence of sodium flowing freely from the ASL and into the cell?

    <p>The cilia will be left in the mucous layer</p> Signup and view all the answers

    Which of the following is the primary cause of Respiratory Distress Syndrome (RDS) in preterm infants?

    <p>Insufficient production of DPPC</p> Signup and view all the answers

    Which method is used to accelerate lung maturation in a mother before delivery?

    <p>Giving the mother glucocorticoids</p> Signup and view all the answers

    What is the molecular ratio that indicates fetal lung maturity?

    <p>DPPC to S ratio of 2 or above</p> Signup and view all the answers

    In adults, Respiratory Distress Syndrome can occur due to which of the following?

    <p>Damage to surfactant-producing pneumocytes</p> Signup and view all the answers

    Which protein complex helps regulate excess elastase activity in the lungs during an infection?

    <p>α1-antiproteinase and elastase complex</p> Signup and view all the answers

    What is the main cause of Respiratory Distress Syndrome (RDS) in preterm infants?

    <p>Insufficient production of surfactant</p> Signup and view all the answers

    Which of the following methods is used to specifically prevent and treat Respiratory Distress Syndrome in newborn infants?

    <p>Directly administering surfactant via intratracheal instillation</p> Signup and view all the answers

    What is the role of DPPC in preventing Respiratory Distress Syndrome (RDS) in preterm infants?

    <p>It decreases the surface tension of the fluid layer lining the alveoli, aiding reinflation</p> Signup and view all the answers

    Which type of cells in the lungs produce and secrete DPPC, a crucial component of lung surfactant?

    <p>Type II pneumocytes</p> Signup and view all the answers

    Which of the following is a potential treatment for Respiratory Distress Syndrome (RDS) in preterm infants?

    <p>Administering exogenous surfactant</p> Signup and view all the answers

    What is the function of lung surfactant in adult lungs?

    <p>To decrease surface tension of the fluid layer lining the alveoli, aiding reinflation</p> Signup and view all the answers

    What are the primary components of lung surfactant?

    <p>Predominantly lipid with some protein and carbohydrate</p> Signup and view all the answers

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