20 Questions
Which hormone is the principle estrogen in premenopausal women?
Estradiol
What is the primary circulating estrogen after menopause?
Estrone
Which type of estrogen is significantly less potent than estradiol and is present in significant amounts during pregnancy?
Estriol
Which type of estrogen is synthetically produced, has long duration, and slow metabolism?
Synthetic Estrogen
What is the main physiological function of estrogen related to the endometrium?
Stimulation of proliferative phase
What is the mechanism of action of conjugated estrogens in target tissues?
Interaction with nuclear receptors Erα and Erβ in target tissues
What is the therapeutic use of postmenopausal hormone therapy (HT) called estrogen-progesterone therapy (EPT)?
Prevention of menopausal symptoms and protection against osteoporosis
How are naturally occurring estrogens and synthetic estrogen analogs primarily administered?
Orally
What is the primary reason for the low bioavailability of orally administered estrogens?
Rapid metabolism and inactivation by the liver
What is the recommended hormone therapy for women who have undergone surgical removal of the uterus?
Unopposed estrogen therapy
Which of the following is NOT a physiological function of estrogen?
Development of male reproductive tract
Which type of estrogen is the principle estrogen in premenopausal women?
Estradiol
What is the primary circulating estrogen after menopause?
Estrone
Which type of estrogen has long duration of action and slow metabolic rate?
Synthetic steroidal estrogen
Which type of estrogen is significantly less potent than estradiol and is present in significant amounts during pregnancy?
Estriol
What is the primary mechanism of action of estrogens in target tissues?
Stimulation of gene transcription
What is the recommended hormone therapy for women who have undergone surgical removal of the uterus?
Unopposed estrogen therapy
What is the main physiological function of conjugated estrogens in target tissues?
Reduction of menopausal symptoms
Why is the bioavailability of orally administered estrogens low?
Rapid metabolism and partial inactivation by the liver
What is the therapeutic use of postmenopausal Hormone Therapy (HT) called estrogen-progesterone therapy (EPT)?
Reducing osteoporosis risk after menopause
Pharmacology questions
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
