Female Reproductive System Diseases
10 Questions
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Female Reproductive System Diseases

This quiz covers various disorders and diseases affecting the female reproductive system, including vulvitis, tumors, and cancers. It also touches on HPV-related conditions. Test your knowledge of these important topics!

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Questions and Answers

What percentage of Low Grade SIL (LSIL) progresses to High Grade SIL (HSIL)?


What is the most common type of cervical carcinoma?

Squamous cell carcinoma

What is the term for abnormal cell growth that may progress to cancer?


What is the term for a cervical tumor that has spread to the myometrium?

<p>Invasive</p> Signup and view all the answers

What is the term for a cervical tumor that has spread to regional lymph nodes?

<p>Metastatic</p> Signup and view all the answers

What is the term for the presence of Mullerian type epithelium in the vagina?

<p>Vaginal adenosis</p> Signup and view all the answers

What is the peak age incidence of cervical intraepithelial neoplasia (CIN)?

<p>30 years</p> Signup and view all the answers

Which type of human papillomavirus (HPV) is associated with condyloma accuminatum?

<p>Low-risk HPV (6, 11, 42, and 44)</p> Signup and view all the answers

What is the major cause of cancer-related deaths in females, particularly in the developing world?

<p>Cervical cancer</p> Signup and view all the answers

What is the zone where the squamo-columnar junction changes location in response to a woman's hormonal status?

<p>Zone of squamo-columnar junction</p> Signup and view all the answers

Study Notes

Female Reproductive System

  • The vulva, vagina, cervix, body of uterus, Fallopian tubes, ovaries, and placenta are parts of the female reproductive system.

Vulvar Disorders

  • Vulvitis, Bartholin cyst, dermatologic disorders, non-specific epithelial disorders, and tumors are common vulvar disorders.
  • Condyloma accuminatum is a type of tumor associated with HPV 6 and HPV 11, usually occurs in multiple lesions, and may coexist with VIN.
  • VIN (Vulvar Intraepithelial Neoplasia) is a type of tumor that may be precancerous.

Vaginal Disorders

  • Vaginitis and primary tumors are rare, but the vagina can be secondarily involved in the spread of cancer or infections from the cervix, vulva, bladder, or rectum.
  • VAIN (Vaginal Intraepithelial Neoplasia) and squamous cell carcinoma are common vaginal disorders.
  • Vaginal adenosis is a condition where Müllerian type epithelium is present in the vagina, often associated with exposure to diethylstilbestrol (DES) in utero.
  • Clear cell carcinoma is a type of tumor that can arise from vaginal adenosis.

Cervical Disorders

  • CIN (Cervical Intraepithelial Neoplasia) is a precursor to cervical cancer, and nearly all invasive cervical SCC arise from CIN.
  • The Pap smear is a successful cancer screening test that can detect preinvasive and potentially curable early cancers.
  • The peak age incidence of CIN is 30 years, and the peak age incidence of cervical cancer is 45 years.
  • HPV is a major risk factor for CIN and invasive carcinoma.

Cervical Intraepithelial Neoplasia (CIN)

  • CIN can progress from low-grade to high-grade or begin as high-grade CIN.
  • CIN I is mild dysplasia, CIN II is moderate dysplasia, and CIN III is severe dysplasia and carcinoma in situ.
  • The Bethesda system is used to classify cytology results, with LSIL (Low-grade SIL) corresponding to CIN I and HSIL (High-grade SIL) corresponding to CIN II and CIN III.

Cervical Carcinoma

  • Squamous cell carcinomas are the most common type of cervical carcinoma (75%).
  • Adenocarcinomas, adenosquamous carcinomas, and small-cell neuroendocrine carcinomas are less common types of cervical carcinoma.
  • Tumors originate in the mucosa and can infiltrate the myometrium and metastasize to regional lymph nodes.

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