10 Questions
What is adenomyosis?
Adenomyosis refers to the growth of the basal layer of the endometrium down into the myometrium.
How does adenomyosis affect the uterus?
It results in an enlarged, globular uterus, often with a thickened uterine wall.
What symptoms may be associated with marked adenomyosis?
Marked adenomyosis may produce menorrhagia, dysmenorrhea, and pelvic pain before the onset of menstruation.
What is required for the diagnosis of adenomyosis in a properly oriented section?
Endometrial glands in the myometrium that are more than 2 to 2.5mm away from the basalis.
Which immunohistochemistry marker confirms the presence of endometrial stroma in adenomyosis?
CD10 positive.
What histopathological features are found in adenomyosis?
Islands of endometrial glands surrounded by endometrial stroma within the myometrium or endometrial stroma exclusively.
How does the presence of endometrial glands in the myometrium contribute to the diagnosis of adenomyosis?
Endometrial glands in the myometrium that are more than 2 to 2.5mm away from the basalis in a properly oriented section are required for diagnosis.
What clinical symptoms are commonly associated with adenomyosis?
Menorrhagia, colicky dysmenorrhoea, and menstrual pain in the sacral or sacrococcygeal regions.
How does adenomyosis affect the size and shape of the uterus?
It results in an enlarged, globular uterus, often with a thickened uterine wall.
Which immunohistochemistry marker confirms the presence of endometrial stroma rather than smooth muscle around the glands in adenomyosis?
CD10 positive
Test your knowledge of adenomyosis, a condition characterized by the growth of endometrial tissue into the myometrium, resulting in an enlarged, globular uterus. This quiz covers the pathology, symptoms, and diagnostic methods associated with adenomyosis.
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