Podcast
Questions and Answers
Which species of mouse is the most widely used in research?
Which species of mouse is the most widely used in research?
- White-footed mouse (Peromyscus leucopus)
- Deer mouse (Peromyscus spp.)
- Field mouse (Microtus spp.)
- Common house mouse (Mus musculus) (correct)
What is the main reason why mice are commonly used in biomedical research?
What is the main reason why mice are commonly used in biomedical research?
- They are genetically modified
- They have unique physiological characteristics
- They are efficient breeders
- They are readily available in international databases (correct)
How are outbred stocks of mice created?
How are outbred stocks of mice created?
- By mating unrelated animals in a closed colony (correct)
- By crossbreeding different species of mice
- By mating closely related animals in an open colony
- By introducing genetic modifications
Which teeth in mice continue to grow throughout their life?
Which teeth in mice continue to grow throughout their life?
What is the condition called when the incisors in mice are not in proper alignment and become overly long?
What is the condition called when the incisors in mice are not in proper alignment and become overly long?
What is the characteristic of mice feces?
What is the characteristic of mice feces?
Why is it important to prevent dehydration and hypoglycemia in mice prior to surgery?
Why is it important to prevent dehydration and hypoglycemia in mice prior to surgery?
Which of the following is true about the gestation length of mice?
Which of the following is true about the gestation length of mice?
At what age do newborn mice develop fur and open their eyes?
At what age do newborn mice develop fur and open their eyes?
What is the average litter size of mice?
What is the average litter size of mice?
Which of the following can decrease reproductive performance in a mouse colony?
Which of the following can decrease reproductive performance in a mouse colony?
Which of the following is the correct definition of an outbred stock?
Which of the following is the correct definition of an outbred stock?
Which of the following mouse stocks is an example of an outbred stock?
Which of the following mouse stocks is an example of an outbred stock?
What is the main difference between an inbred strain and an outbred stock?
What is the main difference between an inbred strain and an outbred stock?
What is the purpose of breeding related individuals for many generations to create an inbred strain?
What is the purpose of breeding related individuals for many generations to create an inbred strain?
Which method is commonly used to assess the activity level of mice during a health check?
Which method is commonly used to assess the activity level of mice during a health check?
Which of the following is a sign of pain in mice according to the Mouse Grimace Scale?
Which of the following is a sign of pain in mice according to the Mouse Grimace Scale?
What is the most common method of euthanasia for laboratory mice?
What is the most common method of euthanasia for laboratory mice?
Which type of caging system is commonly used in most facilities for housing mice?
Which type of caging system is commonly used in most facilities for housing mice?
What is the purpose of providing enrichment for mice?
What is the purpose of providing enrichment for mice?
What is the recommended density for group housing mice in a cage?
What is the recommended density for group housing mice in a cage?
What type of feed is generally used for animals in barrier housing to protect them from exposure to environmental microorganisms?
What type of feed is generally used for animals in barrier housing to protect them from exposure to environmental microorganisms?
Which of the following is NOT a recommended method for handling very young mice (pups less than 10 days old)?
Which of the following is NOT a recommended method for handling very young mice (pups less than 10 days old)?
Which method of handling mice is best for transferring animals between cages?
Which method of handling mice is best for transferring animals between cages?
Which method of restraint is recommended when giving an injection to a mouse by yourself?
Which method of restraint is recommended when giving an injection to a mouse by yourself?
Which method of individual identification of mice requires IACUC approval and should only be used when no other method is feasible?
Which method of individual identification of mice requires IACUC approval and should only be used when no other method is feasible?
Which of the following factors can contribute to aggression in mice?
Which of the following factors can contribute to aggression in mice?
What is the purpose of combining small stable groups of mice at a young age?
What is the purpose of combining small stable groups of mice at a young age?
What is barbering in mice?
What is barbering in mice?
How should mice be handled to avoid tail injuries?
How should mice be handled to avoid tail injuries?
What is the difference between an outbred stock and an inbred strain of mice?
What is the difference between an outbred stock and an inbred strain of mice?
What are some examples of outbred mouse stocks?
What are some examples of outbred mouse stocks?
How are hybrids designated in mouse nomenclature?
How are hybrids designated in mouse nomenclature?
What are some examples of genetically modified mouse models?
What are some examples of genetically modified mouse models?
What are some advantages of using mice in biomedical research?
What are some advantages of using mice in biomedical research?
What is the most widely used species of mouse in research?
What is the most widely used species of mouse in research?
How are outbred stocks created?
How are outbred stocks created?
What are some factors that can contribute to aggression in mice?
What are some factors that can contribute to aggression in mice?
What is barbering in mice and how can it be decreased?
What is barbering in mice and how can it be decreased?
How should mice be handled to avoid tail injuries?
How should mice be handled to avoid tail injuries?
What are some methods of restraint for handling mice?
What are some methods of restraint for handling mice?
What is malocclusion in mice and how can it be treated?
What is malocclusion in mice and how can it be treated?
What is the dental formula of mice?
What is the dental formula of mice?
What are the characteristics of mouse feces and urine?
What are the characteristics of mouse feces and urine?
Why do mice not vomit and how does it affect anesthesia and surgery?
Why do mice not vomit and how does it affect anesthesia and surgery?
What is the purpose of using a red-filtered flashlight during a health check?
What is the purpose of using a red-filtered flashlight during a health check?
What is the Mouse Grimace Scale used for?
What is the Mouse Grimace Scale used for?
What are the acceptable methods of euthanasia for laboratory mice?
What are the acceptable methods of euthanasia for laboratory mice?
What is the significance of the milk spot in newborn mice and what does it indicate?
What is the significance of the milk spot in newborn mice and what does it indicate?
What are the reproductive characteristics of mice?
What are the reproductive characteristics of mice?
What are the behavioral characteristics of mice?
What are the behavioral characteristics of mice?
What factors can decrease reproductive performance in a mouse colony?
What factors can decrease reproductive performance in a mouse colony?
What are the different methods of handling mice and their respective uses?
What are the different methods of handling mice and their respective uses?
What are the different methods of individual identification for mice?
What are the different methods of individual identification for mice?
What are the recommended husbandry practices for mice?
What are the recommended husbandry practices for mice?
What are the characteristics of outbred stocks and inbred strains of mice?
What are the characteristics of outbred stocks and inbred strains of mice?
What are some common types of caging systems used for mice and what are their advantages?
What are some common types of caging systems used for mice and what are their advantages?
What is the purpose of providing enrichment for mice?
What is the purpose of providing enrichment for mice?
What are some examples of enrichment options for mice?
What are some examples of enrichment options for mice?
What are some clinical signs of illness in mice?
What are some clinical signs of illness in mice?
True or false: Mice are the animal species most commonly worked with in biomedical research.
True or false: Mice are the animal species most commonly worked with in biomedical research.
True or false: Genetically modified mice are valuable in many types of research projects, including studies in genetics, cancer, and infectious diseases.
True or false: Genetically modified mice are valuable in many types of research projects, including studies in genetics, cancer, and infectious diseases.
True or false: The most widely used species of mouse in research is the common house mouse, Mus musculus.
True or false: The most widely used species of mouse in research is the common house mouse, Mus musculus.
Outbred stocks are bred to maintain maximum heterozygosity.
Outbred stocks are bred to maintain maximum heterozygosity.
Inbred strains are developed by breeding unrelated individuals for many generations.
Inbred strains are developed by breeding unrelated individuals for many generations.
Hybrids are designated by combining the designations of their parents.
Hybrids are designated by combining the designations of their parents.
Transgenic mice can be infected with the virus that causes HIV.
Transgenic mice can be infected with the virus that causes HIV.
True or false: Mice have canine teeth and premolars.
True or false: Mice have canine teeth and premolars.
True or false: Malocclusion in mice is a condition where the incisors do not wear down properly.
True or false: Malocclusion in mice is a condition where the incisors do not wear down properly.
True or false: Mice can vomit.
True or false: Mice can vomit.
True or false: Female mice have a larger anogenital distance compared to males.
True or false: Female mice have a larger anogenital distance compared to males.
True or false: The gestation length of mice is 19-21 days.
True or false: The gestation length of mice is 19-21 days.
True or false: Mice can be weaned at 21-28 days old.
True or false: Mice can be weaned at 21-28 days old.
True or false: Newborn mice are born with their eyes and ear canals closed.
True or false: Newborn mice are born with their eyes and ear canals closed.
True or false: Female mice exposed to constant light may stop having an estrous cycle.
True or false: Female mice exposed to constant light may stop having an estrous cycle.
True or false: Mice are constantly active during their waking hours?
True or false: Mice are constantly active during their waking hours?
True or false: Male mice tend to be more aggressive than female mice?
True or false: Male mice tend to be more aggressive than female mice?
True or false: Fighting among mice can be increased by changes in group composition?
True or false: Fighting among mice can be increased by changes in group composition?
True or false: Barbering is a behavior where a dominant mouse overgrooms its more subordinate cagemates?
True or false: Barbering is a behavior where a dominant mouse overgrooms its more subordinate cagemates?
True or false: Plastic restraint devices should be used to restrain mice for procedures such as blood draws or substance administration.
True or false: Plastic restraint devices should be used to restrain mice for procedures such as blood draws or substance administration.
True or false: Tunnel handling uses the mouse's natural desire to be in an enclosed tube to transport the animal between cages.
True or false: Tunnel handling uses the mouse's natural desire to be in an enclosed tube to transport the animal between cages.
True or false: Ear notching is a method of marking individual mice.
True or false: Ear notching is a method of marking individual mice.
True or false: Mice should be fed and watered ad libitum, meaning that feed and water is always available.
True or false: Mice should be fed and watered ad libitum, meaning that feed and water is always available.
True or false: Health checks should be conducted on mice only if they show signs of illness.
True or false: Health checks should be conducted on mice only if they show signs of illness.
True or false: Opening the cage lid in an animal work station is necessary to complete a health check when enrichment items are present.
True or false: Opening the cage lid in an animal work station is necessary to complete a health check when enrichment items are present.
True or false: Carbon dioxide (CO2) asphyxiation is the most common method of euthanasia for laboratory mice.
True or false: Carbon dioxide (CO2) asphyxiation is the most common method of euthanasia for laboratory mice.
True or false: Enrichment for mice is provided to exhibit species typical behavior and decrease stress.
True or false: Enrichment for mice is provided to exhibit species typical behavior and decrease stress.
True or false: Microisolation lids are used with solid-bottom plastic cages to prevent exposure of mice to airborne pathogens.
True or false: Microisolation lids are used with solid-bottom plastic cages to prevent exposure of mice to airborne pathogens.
True or false: Wire bottom cages are often used in toxicology research to minimize the mouse's exposure to experimental drugs excreted in urine or feces.
True or false: Wire bottom cages are often used in toxicology research to minimize the mouse's exposure to experimental drugs excreted in urine or feces.
True or false: Sterilized feed is generally used for mice in barrier housing to protect them from exposure to environmental microorganisms.
True or false: Sterilized feed is generally used for mice in barrier housing to protect them from exposure to environmental microorganisms.
