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Questions and Answers
What class of drug is febuxostat?
What is febuxostat used for?
Chronic gout and hyperuricemia
What is the peak effect time of febuxostat?
1 hour
What is the duration of action for febuxostat?
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Which of the following are side effects of febuxostat? (Select all that apply)
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What are some life-threatening conditions associated with febuxostat?
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What should be assessed in a patient taking febuxostat?
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Patients should be taught to increase fluid intake to ______ and avoid alcohol and caffeine.
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Study Notes
Febuxostat Overview
- Classified as an antihyperuricemic antigout drug, effective for managing uric acid levels.
- Primarily indicated for treating chronic gout and hyperuricemia, helping to prevent gout flares.
Pharmacokinetics
- Reaches peak concentration in the bloodstream approximately 1 hour after administration.
- Has a duration of action lasting about 24 hours, allowing for once-daily dosing.
Side Effects
- Common side effects include dizziness, nausea, skin rash, joint pain (arthralgia), and potential gout flares.
- Awareness of these effects is crucial for patient management and monitoring.
Serious Risks
- May pose life-threatening risks for patients with renal, hepatic, cardiac, or neoplastic diseases, necessitating careful assessment before use.
Patient Assessment
- Continuous monitoring for hepatic function is essential, alongside tracking input and output (I&O) and evaluating any signs of hypersensitivity reactions.
Patient Education
- Encourage patients to increase fluid intake to 2 liters per day, which helps to prevent crystallization of uric acid.
- Advise avoidance of alcohol and caffeine, as these can exacerbate hyperuricemia and gout symptoms.
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Description
Test your knowledge about febuxostat with these flashcards. Learn its drug class, uses, peak duration, and potential side effects. Great for students and healthcare professionals interested in pharmacology.