Fatty Liver Disease and RNA-Containing Virus Quiz

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Questions and Answers

What is the most common cause of hepatocellular jaundice?

Liver injury impairing bilirubin conjugation

Which condition is associated with slow/progressive destruction of small intrahepatic bile ducts from chronic inflammation?

Biliary cirrhosis

What factor influences the formation of gallstones in the gallbladder?

Obesity

Which condition may occur if a stone is impacted in the neck of the gallbladder?

Acute cholecystitis Signup and view all the answers

What is the most rapidly increasing incidence of any cancer in the United States?

$Hepatocellular carcinoma$ Signup and view all the answers

What is the most common liver cancer associated with?

HBV infection cases worldwide Signup and view all the answers

What treatment involves removal of the gallbladder?

Cholecystectomy Signup and view all the answers

What is the primary mode of transmission for Hepatitis B?

Blood or body fluids Signup and view all the answers

Which hepatitis virus has an incubation period of 3 to 12 weeks?

Hepatitis C Signup and view all the answers

What are the common types of liver injury mentioned in the text?

Cell necrosis and fatty changes Signup and view all the answers

Which hepatitis virus is transmitted through sharing needles?

Hepatitis D Signup and view all the answers

What is the main diagnostic method for hepatitis mentioned in the text?

Liver enzyme tests Signup and view all the answers

Which hepatitis virus tends to be acute and self-limiting?

Hepatitis E Signup and view all the answers

Which of the following is a main function of the liver?

Detoxification and catabolism of toxins, hormones, and ammonia Signup and view all the answers

What is the primary function of the portal circulation in the liver?

Delivering carbohydrates, proteins, and fats for metabolism Signup and view all the answers

What is a major cause of liver injury?

Excessive alcohol intake Signup and view all the answers

How are gallstones formed?

Due to an imbalance in the components of bile, leading to solidification Signup and view all the answers

What is a consequence of excess alcohol intake on liver structure and function?

Development of fatty liver disease Signup and view all the answers

Which major cause can lead to jaundice?

Obstruction of the bile ducts Signup and view all the answers

What are the common causes of Fatty Liver Disease (FLD)?

Increased fatty acid synthesis, decreased oxidation of fatty acids, impaired release of lipids from carrier proteins Signup and view all the answers

What are the stages of progression in Alcoholic Liver Disease?

Alcoholic fatty liver, alcoholic hepatitis, alcoholic cirrhosis Signup and view all the answers

What are the manifestations of cirrhosis?

Liver failure, portal hypertension, ascites, collateral circulation formation Signup and view all the answers

What results from interrupted blood circulation through the liver in cirrhosis?

Portal hypertension and reduced blood flow Signup and view all the answers

How is Reye Syndrome characterized?

Fatty liver with liver dysfunction, cerebral edema with neurologic dysfunction, mortality rate of 25% Signup and view all the answers

Study Notes

Fatty Liver Disease and Cirrhosis

Fatty Liver Disease (FLD) can be caused by increased fatty acid synthesis, decreased oxidation of fatty acids, or impaired release of lipids from carrier proteins.
FLD is common in heavy drinkers, alcoholics, and can be caused by drugs/chemicals and solvents.
FLD can lead to liver injury, cirrhosis, cancer, and liver failure if not controlled.
Diagnosis of FLD involves liver enzymes (AST/ALT), ultrasound, CT/MRI, and biopsy.
Alcoholic Liver Disease includes three stages of progression: alcoholic fatty liver, alcoholic hepatitis, and alcoholic cirrhosis.
Cirrhosis manifestations include liver failure, portal hypertension, ascites, and collateral circulation formation.
Cirrhosis can result from alcoholic liver disease, chronic hepatitis, severe liver necrosis, and less commonly, repeated liver injury, long-standing bile duct obstruction, or genetic/autoimmune disease.
Manifestations of cirrhosis include hepatic encephalopathy, clotting disorders, increased estrogen levels, and loss of osmotic pressure.
Extensive scarring interrupts and disorganizes lobule architecture, affecting all aspects of liver function in cirrhosis.
Portal hypertension and reduced blood flow are results of interrupted blood circulation through the liver in cirrhosis.
Treatment of cirrhosis and portal hypertension includes endoscopic ligation/ablation of varices, drugs to reduce portal hypertension, and liver transplant.
Reye Syndrome affects infants and children, characterized by fatty liver with liver dysfunction, cerebral edema with neurologic dysfunction, and a mortality rate of 25%.

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