35 Questions
What is the main cause of fatty change (steatosis) in the liver?
Alcohol consumption
Which of the following organs is commonly affected by fatty change (steatosis)?
Liver
What can cause reversible fatty change in parenchymal cells?
Starvation
Which condition is NOT associated with fatty liver?
Hypercholesterolemia
How does fat appear microscopically in fatty liver?
As large vacuoles displacing the nucleus to the periphery of the cell
Which factor can lead to lipid accumulation in the liver?
Defects in fat metabolism pathways
What color does the liver turn grossly in severe fatty change?
Yellow
Which special preparation and stain can be used to distinguish lipid accumulations from water or glycogen accumulations?
Oil Red-O stain
What is the main cause of fatty liver due to an imbalance between the uptake, utilization, and secretion of fat?
Protein malnutrition
Which of the following factors can lead to irreversible fatty liver injury and cell death?
Hepatotoxins
What can lead to lipid accumulation in the liver by disrupting mitochondria and SER?
Alcohol
In fatty liver, how does fat appear microscopically within cells?
Appearing as cytoplasmic droplets
Which organ is commonly affected by fatty change (steatosis) besides the liver?
Skeletal muscle
What special preparation and stain are used to distinguish lipid accumulations from water or glycogen accumulations?
Oil Red-O stain
Which condition is NOT commonly associated with fatty liver?
Heart disease
What effect do hepatotoxins like alcohol have on lipid accumulation in the liver?
Increase lipid accumulation
What color does the liver turn grossly when there is severe fatty change?
Yellow and/or greasy
How does protein malnutrition contribute to fatty change (steatosis) in the liver?
By decreasing the uptake of fats by liver cells
What is the main cause of fatty liver due to an imbalance between the uptake, utilization, and secretion of fat?
Protein malnutrition
How do hepatotoxins like alcohol contribute to lipid accumulation in the liver?
By disrupting mitochondria and SER
Which factor can lead to irreversible fatty liver injury and cell death?
Obesity
How does protein malnutrition contribute to fatty change (steatosis) in the liver?
By disturbing metabolic balance
What special preparation and stain can be used to distinguish lipid accumulations from water or glycogen accumulations?
Oil Red-O stain
Which of the following conditions is associated with cholesterol and cholesterol esters accumulation in addition to fatty liver?
Atherosclerosis
Which organ, besides the liver, is commonly affected by fatty change (steatosis)?
All of them
What effect does hypoxia have on lipid accumulation in the liver?
Disrupts fat uptake
What color does the liver turn grossly when there is severe fatty change?
Yellow and greasy
What is the term for the abnormal accumulation of triglycerides within parenchymal cells?
Fatty change
Which of the following is a common cause of fatty liver besides alcoholic liver disease?
Diabetes Mellitus
In fatty liver, what happens to the nucleus of the cell due to fat vacuoles?
It displaces to the periphery of the cell
Which of the following conditions is NOT associated with fatty liver?
Sickle cell anemia
What effect does anoxia have on lipid accumulation in the liver?
Increases lipid accumulation
What is the primary cause of fatty liver due to an imbalance between the uptake, utilization, and secretion of fat?
Protein malnutrition
Which organelles are disrupted by hepatotoxins like alcohol, leading to lipid accumulation in the liver?
Mitochondria and SER
What stain is used to distinguish lipid accumulations from water or glycogen accumulations?
Oil Red-O stain
Test your knowledge on the abnormal accumulation of triglycerides within parenchymal cells, known as fatty change or steatosis. Explore the causes, effects, and manifestations of this condition in various organs like the liver, heart, kidney, and skeletal muscle.
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