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Questions and Answers
What distinguishes saturated fatty acids from unsaturated fatty acids?
What distinguishes saturated fatty acids from unsaturated fatty acids?
Which category of fatty acids includes those with carbon chains of lengths C12 - C14?
Which category of fatty acids includes those with carbon chains of lengths C12 - C14?
What type of lipids do not contain a carboxylic group?
What type of lipids do not contain a carboxylic group?
Why is the position of double bonds in unsaturated fatty acids numbered from the terminal methyl group?
Why is the position of double bonds in unsaturated fatty acids numbered from the terminal methyl group?
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What structural change does the presence of cis double bonds cause in fatty acids?
What structural change does the presence of cis double bonds cause in fatty acids?
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What is the calorie content of lipids when used as food?
What is the calorie content of lipids when used as food?
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Which of the following is NOT a category of natural fatty acids?
Which of the following is NOT a category of natural fatty acids?
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What is a characteristic of long-chain fatty acids?
What is a characteristic of long-chain fatty acids?
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What characterizes amphipathic molecules?
What characterizes amphipathic molecules?
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What effect does the self-organization of amphipathic molecules have on water molecules?
What effect does the self-organization of amphipathic molecules have on water molecules?
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What happens when lipid molecules have similar sizes for their polar heads and non-polar tails?
What happens when lipid molecules have similar sizes for their polar heads and non-polar tails?
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What is the role of biological membranes within cells?
What is the role of biological membranes within cells?
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Which statement is true regarding the structure of membranes?
Which statement is true regarding the structure of membranes?
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What determines the final structure of a membrane formed by lipid molecules?
What determines the final structure of a membrane formed by lipid molecules?
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How thick is the average cell membrane?
How thick is the average cell membrane?
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What is a micelle formed by lipid molecules characterized by?
What is a micelle formed by lipid molecules characterized by?
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Which lipid has the highest percentage composition in mitochondria membranes?
Which lipid has the highest percentage composition in mitochondria membranes?
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What effect does cholesterol have on the membrane structure?
What effect does cholesterol have on the membrane structure?
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Which lipid is found in erythrocyte membranes in the highest proportion?
Which lipid is found in erythrocyte membranes in the highest proportion?
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How do detergents affect cell membranes?
How do detergents affect cell membranes?
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What role do toxins have concerning cell membranes?
What role do toxins have concerning cell membranes?
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In which type of membrane is glycolipid composition the highest?
In which type of membrane is glycolipid composition the highest?
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What is a key function of cholesterol in the cell membrane?
What is a key function of cholesterol in the cell membrane?
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Which lipid makes up 26% of myelin membranes?
Which lipid makes up 26% of myelin membranes?
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What characterizes facilitated diffusion compared to simple diffusion?
What characterizes facilitated diffusion compared to simple diffusion?
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Which statement about carrier proteins in facilitated diffusion is accurate?
Which statement about carrier proteins in facilitated diffusion is accurate?
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When does the net flow of substances cease in facilitated diffusion?
When does the net flow of substances cease in facilitated diffusion?
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What is a parameter that can be identified in the kinetics of facilitated diffusion?
What is a parameter that can be identified in the kinetics of facilitated diffusion?
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Which statement about saturation kinetics in facilitated diffusion is true?
Which statement about saturation kinetics in facilitated diffusion is true?
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What is a feature of channel proteins involved in facilitated diffusion?
What is a feature of channel proteins involved in facilitated diffusion?
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What distinguishes primary active transport from facilitated diffusion?
What distinguishes primary active transport from facilitated diffusion?
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What type of inhibition can affect the transport process of facilitated diffusion?
What type of inhibition can affect the transport process of facilitated diffusion?
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What type of proteins are completely immersed in the lipid bilayer?
What type of proteins are completely immersed in the lipid bilayer?
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Which experimental technique significantly advanced our knowledge of cell membranes?
Which experimental technique significantly advanced our knowledge of cell membranes?
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What is the primary function of aquaporins in cell membranes?
What is the primary function of aquaporins in cell membranes?
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Which statement about membrane composition is true for erythrocytes?
Which statement about membrane composition is true for erythrocytes?
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What is a characteristic of biological membranes?
What is a characteristic of biological membranes?
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Which of the following membrane compositions is most likely for the internal mitochondrial membrane?
Which of the following membrane compositions is most likely for the internal mitochondrial membrane?
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How do proteins in the cell membrane function with respect to the external environment?
How do proteins in the cell membrane function with respect to the external environment?
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What best describes the arrangement of lipids and proteins in the cell membrane?
What best describes the arrangement of lipids and proteins in the cell membrane?
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What is the primary function of primary active transport?
What is the primary function of primary active transport?
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In secondary active transport, what is the main role of the concentration difference of one substance?
In secondary active transport, what is the main role of the concentration difference of one substance?
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What mechanism is used for the absorption of glucose in intestinal cells?
What mechanism is used for the absorption of glucose in intestinal cells?
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Which process is characterized by the transport of large particles into cells?
Which process is characterized by the transport of large particles into cells?
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What drives ATP synthesis in the mitochondria?
What drives ATP synthesis in the mitochondria?
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Which component is primarily involved in the ATP synthesis process described as chemiosmosis?
Which component is primarily involved in the ATP synthesis process described as chemiosmosis?
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What distinguishes antiport from symport in secondary active transport?
What distinguishes antiport from symport in secondary active transport?
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What role does sodium play in glucose transport in intestinal cells?
What role does sodium play in glucose transport in intestinal cells?
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Which of the following processes requires recognition membrane structures?
Which of the following processes requires recognition membrane structures?
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What is the function of the Na/K ATPase in cells?
What is the function of the Na/K ATPase in cells?
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Study Notes
Lipids
- Lipids are a diverse group of substances.
- They dissolve in organic solvents.
- They do not dissolve in water.
- In animals, lipids are used as food (9.3 kcal/g) and stored as reserve material.
- Lipids are categorized as saponifiable or non-saponifiable.
- Saponifiable lipids contain a carboxyl group (fatty acids and their esters).
- Non-saponifiable lipids do not contain a carboxyl group (alcohols, alkanes, terpenes).
Fatty Acids
- Fatty acids are aliphatic monocarboxylic acids.
- They have a variable number of carbon atoms.
- Even numbers of carbon atoms are common.
- They are usually unbranched and non-cyclic.
- Fatty acids can be categorized as saturated or unsaturated.
- Saturated fatty acids have no double bonds.
- Unsaturated fatty acids have one or more double bonds.
- The position of double bonds is numbered from the terminal methyl (ω) end.
- C4 - C10: short-chain fatty acids e.g., caproic acid
- C12 - C14: medium-chain fatty acids e.g., lauric acid
- C16 - C22: long-chain fatty acids e.g., arachidic acid
Classification of Lipids
- A diagram shows the categorization of lipids.
- Lipids are classified into different groups.
- Lipids include steroids, waxes, sphingolipids, glycerophospholipids, ceramides, cerebrosides, and gangliosides.
- There are also other lipid compounds including vitamins and polyvinyl compounds.
- An example of lipids include Eicosanoids and triacylglycerols(oils, fats).
- There are also Glycerophospholipids, Phosphatogens, Phosphatidates, Sphilingomyelins, Phosphatidyl ethanolamines, Phosphatidyl serines, Phosphatidylcholines, Other phospholipids
Membrane Structure
- Cell membranes consist mainly of phospholipids.
- Membranes have an average thickness of approximately 5 nm.
- The phospholipid bilayer is a key component of cell membranes.
- The bilayer has a polar head and non-polar hydrocarbon tails.
- Lipids and proteins are able to move on the membrane plane.
- Membranes are used as protective barriers.
- They form specialized compartments within a cell.
- They are used to regulate the movement of materials and information between parts of the cell and the external environment.
- The cell's membrane can be analyzed through electron microscopy. At the microscope level, two dark structures are observed, separated by a less dense substance.
Membrane Proteins
- Membrane proteins can be divided into intrinsic and extrinsic proteins.
- Intrinsic proteins extend completely into the lipid bilayer.
- Extrinsic proteins are only partially embedded in the lipid bilayer.
Membrane Water Channels
- Water can cross cell membranes via specialized channel proteins called aquaporins.
Transport Across Biological Membranes
- There are various mechanisms for transporting molecules across cell membranes.
- Transport mechanisms may include uniport, symport, or antiport.
Active Transport
- Active transport moves substances against a concentration gradient.
- Primary active transport uses energy from ATP.
- Secondary active transport couples the transport of two substances.
- Sodium is actively pumped out of the cell, with potassium pumped into the cell by a pump (ATPase Na+/K+).
- The transport of glucose is done by a symport mechanism with the assistance of sodium.
Phagocytosis and Pinocytosis
- These mechanisms are used for transporting large particles into the cell.
- Phagocytosis is when large materials are taken into the cell, and the cell membrane engulfs them.
- Pinocytosis involves taking up smaller liquid droplets.
Exocytosis
- This process allows the cell to secrete substances.
ATP Synthesis
- ATP synthesis occurs through a complex protein mechanism called Chemiosmosis.
- The process exploits the difference in H+ ion concentration.
Partition Coefficient
- The concentration difference of molecules inside the cell membrane versus the concentration outside the cell membrane is dependent on the size and polarity of the molecule.
- A partition coefficient (β) is assigned to determine the degree to which a molecule is concentrated within the membrane and is proportional to the concentration inside the membrane vs in the surrounding solution.
Permeability
- Permeability of various substances depends on the partition coefficient.
- Small, uncharged molecules can cross biological membranes easily.
- Water can be transported easily across membranes by means of specific channel proteins, called "aquaporins".
Biological Membranes are Asymmetrical
- Although cell membranes are similar, the composition of each layer varies. This accounts for the asymmetry of the membrane and each part will have a different composition to the other.
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Description
Test your knowledge on the differences between saturated and unsaturated fatty acids, including their structures, types, and characteristics. Learn about the impact of double bonds and the categorization of fatty acids. This quiz challenges you to differentiate between various forms and properties of fatty acids.