Podcast
Questions and Answers
Which physiological factor can modify the action of drugs in newborns?
Which physiological factor can modify the action of drugs in newborns?
- Plasma protein binding
- Gastric acidity (correct)
- Food
- Body weight
What factor is used to calculate the body surface area for prescribing drug dosage?
What factor is used to calculate the body surface area for prescribing drug dosage?
- Plasma protein binding
- Genetic factors
- Lactation
- Height and weight (correct)
Why is the drug dosage decreased for newborns?
Why is the drug dosage decreased for newborns?
- Inadequate gastric acidity (correct)
- Increased body weight
- Excessive plasma protein binding
- Enhanced food absorption
Which physiological factor is particularly relevant for prescribing drug dosage in children?
Which physiological factor is particularly relevant for prescribing drug dosage in children?
What deficiency in newborns can affect the action of certain drugs like Chloramphenicol?
What deficiency in newborns can affect the action of certain drugs like Chloramphenicol?
Which physiological change in the geriatric age group requires special consideration for drug therapy?
Which physiological change in the geriatric age group requires special consideration for drug therapy?
What adverse effect may antihistaminics cause in children?
What adverse effect may antihistaminics cause in children?
What potential effect may corticosteroids have on growth and development in children?
What potential effect may corticosteroids have on growth and development in children?
Flashcards
Gastric acidity in newborns
Gastric acidity in newborns
Gastric acidity affects drug absorption in newborns.
Body surface area calculation
Body surface area calculation
Height and weight are used to calculate body surface area, crucial for pediatric drug dosage.
Drug dosage decrease for newborns
Drug dosage decrease for newborns
Inadequate gastric acidity leads to decreased drug absorption in newborns
Body Surface Area
Body Surface Area
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Liver enzyme deficiency in newborns
Liver enzyme deficiency in newborns
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Reduced Renal Function
Reduced Renal Function
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Antihistamines effect on children
Antihistamines effect on children
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Corticosteroids effect in children
Corticosteroids effect in children
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Study Notes
Physiological Factors Affecting Drug Action
- Immaturity of hepatic enzyme system: a physiological factor that can modify the action of drugs in newborns
- Body surface area: the factor used to calculate drug dosage for prescribing
- Reduced hepatic metabolism: the reason for decreasing drug dosage in newborns
Newborns and Drug Action
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency: a deficiency in newborns that can affect the action of certain drugs like Chloramphenicol
Geriatric Age Group and Drug Therapy
- Age-related decline in renal function: a physiological change that requires special consideration for drug therapy in the geriatric age group
Adverse Effects of Drugs in Children
- Antihistaminics: may cause antisocial behavior in children
- Corticosteroids: may have a potential effect on growth and development in children
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