Factors Modifying Drug Action Quiz
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Questions and Answers

Which physiological factor can modify the action of drugs in newborns?

  • Plasma protein binding
  • Gastric acidity (correct)
  • Food
  • Body weight
  • What factor is used to calculate the body surface area for prescribing drug dosage?

  • Plasma protein binding
  • Genetic factors
  • Lactation
  • Height and weight (correct)
  • Why is the drug dosage decreased for newborns?

  • Inadequate gastric acidity (correct)
  • Increased body weight
  • Excessive plasma protein binding
  • Enhanced food absorption
  • Which physiological factor is particularly relevant for prescribing drug dosage in children?

    <p>Body surface area</p> Signup and view all the answers

    What deficiency in newborns can affect the action of certain drugs like Chloramphenicol?

    <p>Liver microsomal enzymes (glucuronyl transferase)</p> Signup and view all the answers

    Which physiological change in the geriatric age group requires special consideration for drug therapy?

    <p>Reduced renal function</p> Signup and view all the answers

    What adverse effect may antihistaminics cause in children?

    <p>Hyperactivity</p> Signup and view all the answers

    What potential effect may corticosteroids have on growth and development in children?

    <p>Retardation</p> Signup and view all the answers

    Study Notes

    Physiological Factors Affecting Drug Action

    • Immaturity of hepatic enzyme system: a physiological factor that can modify the action of drugs in newborns
    • Body surface area: the factor used to calculate drug dosage for prescribing
    • Reduced hepatic metabolism: the reason for decreasing drug dosage in newborns

    Newborns and Drug Action

    • Glucose-6-phosphate dehydrogenase (G6PD) deficiency: a deficiency in newborns that can affect the action of certain drugs like Chloramphenicol

    Geriatric Age Group and Drug Therapy

    • Age-related decline in renal function: a physiological change that requires special consideration for drug therapy in the geriatric age group

    Adverse Effects of Drugs in Children

    • Antihistaminics: may cause antisocial behavior in children
    • Corticosteroids: may have a potential effect on growth and development in children

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    Description

    Test your knowledge of factors that modify the action of drugs with this quiz. Explore physiological, pathological, genetic, and environmental factors, as well as drug interactions. Topics include age, sex, pregnancy, plasma protein binding, body weight, lactation, food, and allergies. Perfect for students of pharmacology and related fields.

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